Literature DB >> 33775693

CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing.

Andrew B Lehr1, Arvind Kumar2, Christian Tetzlaff3, Torkel Hafting4, Marianne Fyhn5, Tristan M Stöber6.   

Abstract

Hippocampal region CA2 has received increased attention due to its importance in social recognition memory. While its specific function remains to be identified, there are indications that CA2 plays a major role in a variety of situations, widely extending beyond social memory. In this targeted review, we highlight lines of research which have begun to converge on a more fundamental role for CA2 in hippocampus-dependent memory processing. We discuss recent proposals that speak to the computations CA2 may perform within the hippocampal circuit.
Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  CA2; Hippocampus; Learning and memory; Social memory

Year:  2021        PMID: 33775693     DOI: 10.1016/j.neubiorev.2021.03.020

Source DB:  PubMed          Journal:  Neurosci Biobehav Rev        ISSN: 0149-7634            Impact factor:   8.989


  6 in total

1.  Differential involvement of CA2 in internally vs. externally driven hippocampal sequences.

Authors:  Andrew B Lehr; Tristan M Stöber
Journal:  Proc Natl Acad Sci U S A       Date:  2021-09-21       Impact factor: 11.205

2.  Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy.

Authors:  Alexander C Whitebirch; John J LaFrancois; Swati Jain; Paige Leary; Bina Santoro; Steven A Siegelbaum; Helen E Scharfman
Journal:  Neuron       Date:  2022-08-19       Impact factor: 18.688

3.  Neuromodulator-dependent synaptic tagging and capture retroactively controls neural coding in spiking neural networks.

Authors:  Andrew B Lehr; Jannik Luboeinski; Christian Tetzlaff
Journal:  Sci Rep       Date:  2022-10-22       Impact factor: 4.996

4.  A dorsal CA2 to ventral CA1 circuit contributes to oxytocinergic modulation of long-term social recognition memory.

Authors:  Tsung-Chih Tsai; Yi-Syuan Fang; Yu-Chieh Hung; Ling-Chien Hung; Kuei-Sen Hsu
Journal:  J Biomed Sci       Date:  2022-07-10       Impact factor: 12.771

Review 5.  Alteration of Neural Pathways and Its Implications in Alzheimer's Disease.

Authors:  Sujin Kim; Yunkwon Nam; Hyeon Soo Kim; Haram Jung; Seong Gak Jeon; Sang Bum Hong; Minho Moon
Journal:  Biomedicines       Date:  2022-04-04

6.  Kainate receptors in the CA2 region of the hippocampus.

Authors:  Yuniesky Andrade-Talavera; Antonio Rodríguez-Moreno
Journal:  Neural Regen Res       Date:  2023-02       Impact factor: 6.058

  6 in total

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