Stuart J H Biddle1, Joseph Henson2, Melanie J Davies3, Kamlesh Khunti4, Stephen Sutton5, Thomas Yates3, Charlotte L Edwardson3. 1. Centre for Health Research, University of Southern Queensland, Springfield, Australia. Electronic address: stuart.biddle@usq.edu.au. 2. Diabetes Research Centre, University of Leicester, Leicester General Hospital Leicester LE5 4PW, UK; NIHR Leicester Biomedical Research Centre, Leicester General Hospital, Leicester, LE5 4PW, UK. 3. Diabetes Research Centre, University of Leicester, Leicester General Hospital Leicester LE5 4PW, UK; NIHR Leicester Biomedical Research Centre, Leicester General Hospital, Leicester, LE5 4PW, UK; Leicester Diabetes Centre, University Hospitals of Leicester, Leicester General Hospital, Leicester, LE5 4PW, UK. 4. Diabetes Research Centre, University of Leicester, Leicester General Hospital Leicester LE5 4PW, UK; Leicester Diabetes Centre, University Hospitals of Leicester, Leicester General Hospital, Leicester, LE5 4PW, UK; NIHR Applied Health Research Collaboration - East Midlands (NIHR ARC-EM), Leicester Diabetes Centre, Leicester, UK. 5. Behavioural Science Group, Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Abstract
OBJECTIVE: Assessment of sitting has been challenging and nuances in the length of sitting are often missed. METHODS: The present study assessed total, short and prolonged sitting time, and number of breaks from sitting, and their association with anxiety, depression, and health-related quality of life (HRQoL). Adults (M=59.1 years) in three studies (n=1,574) wore the activPAL accelerometer (thigh) to obtain a measure of sitting, and the Actigraph accelerometer (hip) for estimating moderate-to-vigorous physical activity (MVPA). Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale, and HRQoL using the EQ-5D-5L (for health state and utility scores). Generalised linear modelling tested associations. RESULTS: Total and prolonged sitting were associated with higher depression [total: β = 0.132 (0.010, 0.254); prolonged: β = 0.178 (0.053, 0.304)] and worse HRQoL health state scores [(total: β = -0.985 (-1.471, -0.499); prolonged: β = -0.834 (-1.301, -0.367)] and utility scores [(total: β = -0.008 (-0.012, -0.003); prolonged: β = -0.008 (-0.012, -0.004)], after controlling for covariates. MVPA was associated with better HRQoL health state and utility scores [health state: β =0.554 (0.187, 0.922); utility: β = 0.001 (0.001, 0.002)]. Total and prolonged sitting were associated with a 14% increased odds of being in the borderline/abnormal category for depression. No interactions were observed between MVPA status (active vs. inactive) and total or prolonged sitting. Anxiety was unrelated to any sitting variable. CONCLUSION: Device-based measures of both total and prolonged sitting time were associated with depression and health-related quality of life, but not anxiety.
OBJECTIVE: Assessment of sitting has been challenging and nuances in the length of sitting are often missed. METHODS: The present study assessed total, short and prolonged sitting time, and number of breaks from sitting, and their association with anxiety, depression, and health-related quality of life (HRQoL). Adults (M=59.1 years) in three studies (n=1,574) wore the activPAL accelerometer (thigh) to obtain a measure of sitting, and the Actigraph accelerometer (hip) for estimating moderate-to-vigorous physical activity (MVPA). Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale, and HRQoL using the EQ-5D-5L (for health state and utility scores). Generalised linear modelling tested associations. RESULTS: Total and prolonged sitting were associated with higher depression [total: β = 0.132 (0.010, 0.254); prolonged: β = 0.178 (0.053, 0.304)] and worse HRQoL health state scores [(total: β = -0.985 (-1.471, -0.499); prolonged: β = -0.834 (-1.301, -0.367)] and utility scores [(total: β = -0.008 (-0.012, -0.003); prolonged: β = -0.008 (-0.012, -0.004)], after controlling for covariates. MVPA was associated with better HRQoL health state and utility scores [health state: β =0.554 (0.187, 0.922); utility: β = 0.001 (0.001, 0.002)]. Total and prolonged sitting were associated with a 14% increased odds of being in the borderline/abnormal category for depression. No interactions were observed between MVPA status (active vs. inactive) and total or prolonged sitting. Anxiety was unrelated to any sitting variable. CONCLUSION: Device-based measures of both total and prolonged sitting time were associated with depression and health-related quality of life, but not anxiety.
Authors: Kaija Appelqvist-Schmidlechner; Jani Raitanen; Tommi Vasankari; Heikki Kyröläinen; Arja Häkkinen; Tuomas Honkanen; Jani P Vaara Journal: Front Public Health Date: 2022-02-18
Authors: Sarah Morton; Claire Fitzsimons; Ruth Jepson; David H Saunders; Divya Sivaramakrishnan; Ailsa Niven Journal: Front Sports Act Living Date: 2022-07-29