STUDY DESIGN: Chart reviews were combined with neurological and functional outcome data obtained from the prospective European Multicenter Study on Spinal Cord Injury (EMSCI, www.emsci.org). OBJECTIVES: To determine if strict physical isolation of multidrug-resistant organisms (MDRO)-positive patients negatively affects neurological recovery and functional outcome in the first year after acute spinal cord injury (SCI). SETTING: SCI Center Heidelberg University Hospital. METHODS: Individuals with acute (< 6 weeks) traumatic or ischemic SCI were included. During primary comprehensive care, isolated MDRO-positive patients (n = 13) were compared with a MDRO-negative control group (n = 13) matched for functional (Spinal Cord Independence Measure-SCIM) and neurological impairment (motor scores based on the International Standards for Neurological Classification of Spinal Cord Injury-ISNCSCI) at an early stage up to 40 days after SCI. SCIM scores and motor scores were obtained at 12 weeks (intermediate stage) and 24 or 48 weeks (late stage) after SCI. RESULTS: Isolated MDRO-positive (median duration of hospitalization: 175 days, 39% of inpatient stay under isolation measures) and non-isolated MDRO-negative (median duration of hospitalization: 161 days) patients showed functional and neurological improvements, which were not statistically different between groups at the intermediate and late stage. CONCLUSION: Prolonged isolation due to MDRO colonization for over a third of the inpatient comprehensive care period does not appear to impair neurological recovery and functional outcome within the first year after SCI.
STUDY DESIGN: Chart reviews were combined with neurological and functional outcome data obtained from the prospective European Multicenter Study on Spinal Cord Injury (EMSCI, www.emsci.org). OBJECTIVES: To determine if strict physical isolation of multidrug-resistant organisms (MDRO)-positive patients negatively affects neurological recovery and functional outcome in the first year after acute spinal cord injury (SCI). SETTING: SCI Center Heidelberg University Hospital. METHODS: Individuals with acute (< 6 weeks) traumatic or ischemic SCI were included. During primary comprehensive care, isolated MDRO-positive patients (n = 13) were compared with a MDRO-negative control group (n = 13) matched for functional (Spinal Cord Independence Measure-SCIM) and neurological impairment (motor scores based on the International Standards for Neurological Classification of Spinal Cord Injury-ISNCSCI) at an early stage up to 40 days after SCI. SCIM scores and motor scores were obtained at 12 weeks (intermediate stage) and 24 or 48 weeks (late stage) after SCI. RESULTS: Isolated MDRO-positive (median duration of hospitalization: 175 days, 39% of inpatient stay under isolation measures) and non-isolated MDRO-negative (median duration of hospitalization: 161 days) patients showed functional and neurological improvements, which were not statistically different between groups at the intermediate and late stage. CONCLUSION: Prolonged isolation due to MDRO colonization for over a third of the inpatient comprehensive care period does not appear to impair neurological recovery and functional outcome within the first year after SCI.
Authors: M Itzkovich; I Gelernter; F Biering-Sorensen; C Weeks; M T Laramee; B C Craven; M Tonack; S L Hitzig; E Glaser; G Zeilig; S Aito; G Scivoletto; M Mecci; R J Chadwick; W S El Masry; A Osman; C A Glass; P Silva; B M Soni; B P Gardner; G Savic; E M Bergström; V Bluvshtein; J Ronen; A Catz Journal: Disabil Rehabil Date: 2007-03-05 Impact factor: 3.033
Authors: R Nair; E N Perencevich; M Goto; D J Livorsi; E Balkenende; E Kiscaden; M L Schweizer Journal: Clin Microbiol Infect Date: 2020-01-30 Impact factor: 8.067
Authors: Salva N Balbale; Jennifer N Hill; Marylou Guihan; Timothy P Hogan; Kenzie A Cameron; Barry Goldstein; Charlesnika T Evans Journal: Implement Sci Date: 2015-09-09 Impact factor: 7.327
Authors: J D Rollnik; M Bertram; C Bucka; M Hartwich; M Jöbges; G Ketter; B Leineweber; M Mertl-Rötzer; D A Nowak; T Platz; K Scheidtmann; R Thomas; F von Rosen; C W Wallesch; H Woldag; P Peschel; J Mehrholz; M Pohl Journal: BMC Neurol Date: 2017-03-20 Impact factor: 2.474