Literature DB >> 33768433

Effect of Preoperative Weight Loss and Baseline Comorbidity on Short-Term Complications and Reoperations After Laparoscopic Roux-en-Y Gastric Bypass in 2,067 Patients.

Tom Wiggins1, Dimitri J Pournaras1, Elena Priestman1, Alan Osborne1, Daniel R Titcomb1, Ian Finlay1, James Hopkins1, Marianne Hollyman1, Matthew Mason1, Hamish Noble1, David Mahon1, Richard Welbourn2.   

Abstract

PURPOSE: Decreasing popularity of Roux-en-Y gastric bypass (RYGB) in bariatric-metabolic surgery may be due to higher perceived peri-operative complications. There are few studies on whether preoperative weight loss can reduce complications or reoperations following RYGB. We investigated this using a standardised operative technique.
MATERIALS AND METHODS: Retrospective single-centre study of RYGB from 2004 to 2019 using a prospective database. Preoperative behavioural management included intentional weight loss. Maximum preoperative weight, weight on the day of operation, and Obesity-Surgery Mortality Risk Score (OS-MRS) class were recorded. Short-term outcomes (post-operative stay, 30-day complication and reoperation rates) were analysed.
RESULTS: In 2,067 RYGB patients (1,901 primary and 166 revisional), median preoperative total body weight loss (TWL) was 6.2% (IQR: 2.5-10.7%). The median age was 46 (interquartile range (IQR) 38-54) and 80.4% were female (n=1,661). For primary surgery, the median body mass index (BMI) was 47.6 kg/m2 (IQR: 43.1-53.3). Excluding the 100-procedure learning curve, the complication rate for primary cases was 4.4% and reoperation rate of 2.8% and one peri-operative mortality (0.06%). OS-MRS ≥2 (class B or C) predicted higher risk of complications (6.1%) compared to those with a score <2 (class A) (3.8%, p=0.021), but not reoperations. Five percent preoperative TWL did not decrease complications compared to <5% TWL. Patients with ≥10% TWL had greater baseline risk and had an increased risk of complications (6.6% vs 3.7%, p=0.017) and reoperations (4.5% vs 2.7%, p<0.001).
CONCLUSIONS: RYGB performed using a standardised technique has low overall risk. The influence of preoperative weight loss on outcomes was inconsistent.

Entities:  

Keywords:  Obesity Surgery-Mortality Risk Score; Obesity surgery; Roux en Y gastric bypass; bariatric surgery; perioperative complications; short-term outcomes

Mesh:

Year:  2021        PMID: 33768433     DOI: 10.1007/s11695-021-05331-y

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  46 in total

1.  Bariatric surgery versus conventional medical therapy for type 2 diabetes.

Authors:  Geltrude Mingrone; Simona Panunzi; Andrea De Gaetano; Caterina Guidone; Amerigo Iaconelli; Laura Leccesi; Giuseppe Nanni; Alfons Pomp; Marco Castagneto; Giovanni Ghirlanda; Francesco Rubino
Journal:  N Engl J Med       Date:  2012-03-26       Impact factor: 91.245

2.  Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes.

Authors:  Philip R Schauer; Deepak L Bhatt; John P Kirwan; Kathy Wolski; Ali Aminian; Stacy A Brethauer; Sankar D Navaneethan; Rishi P Singh; Claire E Pothier; Steven E Nissen; Sangeeta R Kashyap
Journal:  N Engl J Med       Date:  2017-02-16       Impact factor: 91.245

Review 3.  Rethinking Patient and Medical Professional Perspectives on Bariatric Surgery as a Medically Necessary Treatment.

Authors:  Gretchen E Ames; Jennifer R Maynard; Maria L Collazo-Clavell; Matthew M Clark; Karen B Grothe; Enrique F Elli
Journal:  Mayo Clin Proc       Date:  2020-03       Impact factor: 7.616

4.  Bariatric surgery and long-term cardiovascular events.

Authors:  Lars Sjöström; Markku Peltonen; Peter Jacobson; C David Sjöström; Kristjan Karason; Hans Wedel; Sofie Ahlin; Åsa Anveden; Calle Bengtsson; Gerd Bergmark; Claude Bouchard; Björn Carlsson; Sven Dahlgren; Jan Karlsson; Anna-Karin Lindroos; Hans Lönroth; Kristina Narbro; Ingmar Näslund; Torsten Olbers; Per-Arne Svensson; Lena M S Carlsson
Journal:  JAMA       Date:  2012-01-04       Impact factor: 56.272

5.  Bariatric Surgery Worldwide: Baseline Demographic Description and One-Year Outcomes from the Fourth IFSO Global Registry Report 2018.

Authors:  Richard Welbourn; Marianne Hollyman; Robin Kinsman; John Dixon; Ronald Liem; Johan Ottosson; Almino Ramos; Villy Våge; Salman Al-Sabah; Wendy Brown; Ricardo Cohen; Peter Walton; Jacques Himpens
Journal:  Obes Surg       Date:  2018-11-12       Impact factor: 4.129

6.  Cancer Risk Following Bariatric Surgery-Systematic Review and Meta-analysis of National Population-Based Cohort Studies.

Authors:  Tom Wiggins; Stefan S Antonowicz; Sheraz R Markar
Journal:  Obes Surg       Date:  2019-03       Impact factor: 4.129

7.  Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial.

Authors:  Paulina Salminen; Mika Helmiö; Jari Ovaska; Anne Juuti; Marja Leivonen; Pipsa Peromaa-Haavisto; Saija Hurme; Minna Soinio; Pirjo Nuutila; Mikael Victorzon
Journal:  JAMA       Date:  2018-01-16       Impact factor: 56.272

8.  Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial.

Authors:  Lars Sjöström; Anders Gummesson; C David Sjöström; Kristina Narbro; Markku Peltonen; Hans Wedel; Calle Bengtsson; Claude Bouchard; Björn Carlsson; Sven Dahlgren; Peter Jacobson; Kristjan Karason; Jan Karlsson; Bo Larsson; Anna-Karin Lindroos; Hans Lönroth; Ingmar Näslund; Torsten Olbers; Kaj Stenlöf; Jarl Torgerson; Lena M S Carlsson
Journal:  Lancet Oncol       Date:  2009-06-24       Impact factor: 41.316

9.  Association of bariatric surgery with all-cause mortality and incidence of obesity-related disease at a population level: A systematic review and meta-analysis.

Authors:  Tom Wiggins; Nadia Guidozzi; Richard Welbourn; Ahmed R Ahmed; Sheraz R Markar
Journal:  PLoS Med       Date:  2020-07-28       Impact factor: 11.069

Review 10.  Metabolic surgery for the treatment of type 2 diabetes in obese individuals.

Authors:  David E Cummings; Francesco Rubino
Journal:  Diabetologia       Date:  2017-12-09       Impact factor: 10.122

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  1 in total

1.  Medication following bariatric surgery for type 2 diabetes mellitus (BY-PLUS) study: rationale and design of a randomised controlled study.

Authors:  Alexis Sudlow; Alexander Dimitri Miras; Ricardo Vitor Cohen; Hassan Kahal; Jill Townley; Helen Heneghan; Carel Le Roux; Dimitri J Pournaras
Journal:  BMJ Open       Date:  2022-07-25       Impact factor: 3.006

  1 in total

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