Literature DB >> 33768222

Single dose of a mRNA SARS-CoV-2 vaccine is associated with lower nasopharyngeal viral load among nursing home residents with asymptomatic COVID-19.

M Catherine McEllistrem1, Cornelius J Clancy1,2, Deanna J Buehrle1, Aaron Lucas1,2, Brooke K Decker1,2.   

Abstract

In nursing home residents with asymptomatic COVID-19 diagnosed through twice-weekly surveillance testing, single dose BNT162b2 vaccination (Pfizer-BioNTech) was associated with -2.4 mean log10 lower nasopharyngeal viral load than detected in absence of vaccination (p=0.004). Since viral load is linked to transmission, single dose mRNA SARS-CoV-2 vaccination may help control outbreaks.
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Asymptomatic; COVID-19; Cycle Threshold; SARS-CoV-2; Viral Load

Year:  2021        PMID： 33768222      PMCID： PMC8083695          DOI： 10.1093/cid/ciab263

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  16 in total

1.  Indirect Protection by Reducing Transmission: Ending the Pandemic With Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination.

Authors:  Aaron Richterman; Eric A Meyerowitz; Muge Cevik
Journal:  Open Forum Infect Dis       Date:  2021-05-19       Impact factor: 3.835

2.  Emerging Evidence on Effectiveness of COVID-19 Vaccines Among Residents of Long-Term Care Facilities.

Authors:  Maximilian Salcher-Konrad; Siân Smith; Adelina Comas-Herrera
Journal:  J Am Med Dir Assoc       Date:  2021-05-25       Impact factor: 4.669

3.  Performance Characteristics of the Abbott BinaxNOW SARS-CoV-2 Antigen Test in Comparison to Real-Time Reverse Transcriptase PCR and Viral Culture in Community Testing Sites during November 2020.

Authors:  Olivia Almendares; Jessica L Prince-Guerra; Leisha D Nolen; Jayleen K L Gunn; Ariella P Dale; Sean A Buono; Molly Deutsch-Feldman; Suganthi Suppiah; LiJuan Hao; Yan Zeng; Valerie A Stevens; Kristen Knipe; Justine Pompey; Christine Atherstone; David P Bui; Tracy Powell; Azaibi Tamin; Jennifer L Harcourt; Marla Petway; Caitlin Bohannon; Jennifer M Folster; Adam MacNeil; Reynolds Salerno; Wendi Kuhnert-Tallman; Jacqueline E Tate; Natalie Thornburg; Hannah L Kirking; Khalilullah Sheiban; Julie Kudrna; Theresa Cullen; Kenneth K Komatsu; Julie M Villanueva; Dale A Rose; John C Neatherlin; Mark Anderson; Paul A Rota; Margaret A Honein; William A Bower
Journal:  J Clin Microbiol       Date:  2021-10-27       Impact factor: 5.948

4.  Clinical Phenotype and Contagiousness of Early Breakthrough SARS-CoV-2 Infections after BNT162b2 COVID-19 mRNA Vaccine: A Parallel Cohort Study in Healthcare Workers.

Authors:  Mattia Trunfio; Federica Verga; Valeria Ghisetti; Elisa Burdino; Teresa Emanuele; Stefano Bonora; Giovanni Di Perri; Andrea Calcagno
Journal:  Vaccines (Basel)       Date:  2021-11-23

5.  The impact of COVID-19 epidemic phase and changes in mean viral loads: implications for SARS-CoV-2 testing strategies.

Authors:  Cameron Buckley; Claire Yt Wang; Mark D Chatfield; Cheryl Bletchly; Patrick Harris; David Whiley
Journal:  Diagn Microbiol Infect Dis       Date:  2021-11-19       Impact factor: 2.803

6.  Breakthrough infections with the SARS-CoV-2 Delta variant: vaccinations halved transmission risk.

Authors:  L Hsu; J Hurraß; A Kossow; J Klobucnik; J Nießen; G A Wiesmüller; B Grüne; C Joisten
Journal:  Public Health       Date:  2022-01-11       Impact factor: 2.427

7.  Receptor binding domain-IgG levels correlate with protection in residents facing SARS-CoV-2 B.1.1.7 outbreaks.

Authors:  Hubert Blain; Edouard Tuaillon; Lucie Gamon; Amandine Pisoni; Stéphanie Miot; Valentin Delpui; Nejm Si-Mohamed; Clémence Niel; Yves Rolland; Brigitte Montes; Soraya Groc; Sophia Rafasse; Anne-Marie Dupuy; Nathalie Gros; Delphine Muriaux; Marie-Christine Picot; Jean Bousquet
Journal:  Allergy       Date:  2021-10-29       Impact factor: 14.710

8.  Transmission of SARS-CoV-2 variant B.1.1.7 among vaccinated health care workers.

Authors:  Petros Ioannou; Stamatis Karakonstantis; Eirini Astrinaki; Stamatina Saplamidou; Efsevia Vitsaxaki; Georgios Hamilos; George Sourvinos; Diamantis P Kofteridis
Journal:  Infect Dis (Lond)       Date:  2021-06-26

Review 9.  SARS-CoV-2 mRNA Vaccine Breakthrough Infections in Fully Vaccinated Healthcare Personnel: A Systematic Review.

Authors:  Caterina Ledda; Claudio Costantino; Giuseppe Motta; Rosario Cunsolo; Patrizia Stracquadanio; Giuseppe Liberti; Helena C Maltezou; Venerando Rapisarda
Journal:  Trop Med Infect Dis       Date:  2022-01-13

Review 10.  Factors influencing SARS-CoV-2 RNA concentrations in wastewater up to the sampling stage: A systematic review.

Authors:  Xander Bertels; Phaedra Demeyer; Siel Van den Bogaert; Tim Boogaerts; Alexander L N van Nuijs; Peter Delputte; Lies Lahousse
Journal:  Sci Total Environ       Date:  2022-01-20       Impact factor: 10.753
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