Literature DB >> 33766691

Recent advances in the design of microfluidic technologies for the manufacture of drug releasing particles.

Alejandro Forigua1, Rebecca L Kirsch2, Stephanie M Willerth3, Katherine S Elvira4.   

Abstract

Drug releasing particles are valued for their ability to deliver therapeutics to targeted locations and for their controllable release patterns. The development of microfluidic technologies, which are designed specifically to manipulate small amounts of fluids, to manufacture particles for drug delivery applications reflects a recent trend due to the advantages they confer in terms of control over particle size and material composition. This review takes a comprehensive look at the different types of microfluidic devices used to fabricate such particles from different types of biomaterials, and at how the on-chip features enable the production of particles with different types of properties. The review concludes by suggesting avenues for future work that will enable these technologies to fulfill their potential and be used in industrial settings for the manufacture of drug releasing particles with unique capabilities.
Copyright © 2021 Elsevier B.V. All rights reserved.

Keywords:  Droplets; Drug release; Microfluidics; Microparticles; Nanoparticles

Year:  2021        PMID: 33766691     DOI: 10.1016/j.jconrel.2021.03.019

Source DB:  PubMed          Journal:  J Control Release        ISSN: 0168-3659            Impact factor:   9.776


  3 in total

Review 1.  High-Throughput Synthesis of Thin Films for the Discovery of Energy Materials: A Perspective.

Authors:  Shahram Moradi; Soumya Kundu; Makhsud I Saidaminov
Journal:  ACS Mater Au       Date:  2022-05-30

2.  Single pot organic solvent-free thermocycling technology for siRNA-ionizable LNPs: a proof-of-concept approach for alternative to microfluidics.

Authors:  Anindita De; Young Tag Ko
Journal:  Drug Deliv       Date:  2022-12       Impact factor: 6.819

Review 3.  Microfluidic Synthesis, Control, and Sensing of Magnetic Nanoparticles: A Review.

Authors:  Roozbeh Abedini-Nassab; Mahrad Pouryosef Miandoab; Merivan Şaşmaz
Journal:  Micromachines (Basel)       Date:  2021-06-29       Impact factor: 2.891

  3 in total

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