Literature DB >> 33764170

Leucine augments specific skeletal muscle mitochondrial respiratory pathways during recovery following 7 days of physical inactivity in older adults.

Emily J Arentson-Lantz1,2, Jasmine Mikovic3, Nisha Bhattarai4, Christopher S Fry1,2, Séverine Lamon3, Craig Porter4, Douglas Paddon-Jones1,2.   

Abstract

In older adults, leucine mitigated the loss of insulin sensitivity associated with muscular disuse. Leucine supplementation increased mitochondrial respiration and reduced a marker of oxidative stress following periods of disuse and rehabilitation.

Entities:  

Keywords:  aging; bed rest; dietary supplementation; nutrition

Mesh：

Substances：

Year:  2021        PMID： 33764170      PMCID： PMC8354827          DOI： 10.1152/japplphysiol.00810.2020

Source DB:  PubMed          Journal:  J Appl Physiol (1985)        ISSN： 0161-7567


  48 in total

Review 1.  Percutaneous needle biopsy of skeletal muscle in physiological and clinical research.

Authors:  J Bergstrom
Journal:  Scand J Clin Lab Invest       Date:  1975-11       Impact factor: 1.713

2.  The time course of the adaptations of human muscle proteome to bed rest and the underlying mechanisms.

Authors:  Lorenza Brocca; Jessica Cannavino; Luisa Coletto; Gianni Biolo; Marco Sandri; Roberto Bottinelli; Maria Antonietta Pellegrino
Journal:  J Physiol       Date:  2012-07-30       Impact factor: 5.182

3.  Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2 O2 emission.

Authors:  Marlou L Dirks; Paula M Miotto; Gijs H Goossens; Joan M Senden; Heather L Petrick; Janneau van Kranenburg; Luc J C van Loon; Graham P Holloway
Journal:  J Physiol       Date:  2019-12-26       Impact factor: 5.182

4.  Decline in skeletal muscle mitochondrial function with aging in humans.

Authors:  Kevin R Short; Maureen L Bigelow; Jane Kahl; Ravinder Singh; Jill Coenen-Schimke; Sreekumar Raghavakaimal; K Sreekumaran Nair
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-30       Impact factor: 11.205

Review 5.  Oxidative stress and disuse muscle atrophy: cause or consequence?

Authors:  Scott K Powers; Ashley J Smuder; Andrew R Judge
Journal:  Curr Opin Clin Nutr Metab Care       Date:  2012-05       Impact factor: 4.294

6.  Skeletal muscle mitochondrial H2 O2 emission increases with immobilization and decreases after aerobic training in young and older men.

Authors:  Martin Gram; Andreas Vigelsø; Takashi Yokota; Jørn Wulff Helge; Flemming Dela; Martin Hey-Mogensen
Journal:  J Physiol       Date:  2015-07-27       Impact factor: 5.182

7.  Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein.

Authors:  Shanon L Casperson; Melinda Sheffield-Moore; Susan J Hewlings; Douglas Paddon-Jones
Journal:  Clin Nutr       Date:  2012-02-20       Impact factor: 7.324

8.  The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study.

Authors:  Bret H Goodpaster; Seok Won Park; Tamara B Harris; Steven B Kritchevsky; Michael Nevitt; Ann V Schwartz; Eleanor M Simonsick; Frances A Tylavsky; Marjolein Visser; Anne B Newman
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2006-10       Impact factor: 6.053

9.  Fourteen days of bed rest induces a decline in satellite cell content and robust atrophy of skeletal muscle fibers in middle-aged adults.

Authors:  Emily J Arentson-Lantz; Kirk L English; Douglas Paddon-Jones; Christopher S Fry
Journal:  J Appl Physiol (1985)       Date:  2016-01-21

10.  Two weeks of one-leg immobilization decreases skeletal muscle respiratory capacity equally in young and elderly men.

Authors:  Martin Gram; Andreas Vigelsø; Takashi Yokota; Christina Neigaard Hansen; Jørn Wulff Helge; Martin Hey-Mogensen; Flemming Dela
Journal:  Exp Gerontol       Date:  2014-09-02       Impact factor: 4.032
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  2 in total

Review 1.  Cardiovasomobility: an integrative understanding of how disuse impacts cardiovascular and skeletal muscle health.

Authors:  Joel D Trinity; Micah J Drummond; Caitlin C Fermoyle; Alec I McKenzie; Mark A Supiano; Russell S Richardson
Journal:  J Appl Physiol (1985)       Date:  2022-02-03

2.  No effect of five days of bed rest or short-term resistance exercise prehabilitation on markers of skeletal muscle mitochondrial content and dynamics in older adults.

Authors:  Ryan N Marshall; Benoit Smeuninx; Alex P Seabright; Paul T Morgan; Philip J Atherton; Andrew Philp; Leigh Breen
Journal:  Physiol Rep       Date:  2022-07
  2 in total

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