Maja Striteska1,2, Lukas Skoloudik1, Martin Valis3, Jan Mejzlik1, Katerina Trnkova2, Martin Chovanec2, Oliver Profant2,4, Viktor Chrobok1, Jan Kremlacek5. 1. Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Kralove, Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic. 2. Department of Otorhinolaryngology, Charles University in Prague, 3rd Faculty of Medicine, University Hospital Kralovske Vinohrady, Czech Republic. 3. Department of Neurology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic. 4. Department of Auditory Neuroscience, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic. 5. Department of Biophysics and Department of Pathological Physiology, Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic.
Abstract
BACKGROUND: The availability and development of methods testing the vestibuloocular reflex (VOR) brought a broader view into the lateral semicircular canal (L-SCC) function. However, the higher number of evaluated parameters makes more difficult the specialist's diagnose-making process. PURPOSE: To provide medical specialists, a new diagnostic-graphic tool, Estimated Vestibulogram- EVEST, enabling a quick and easy-to-read visualization and comparison of the VOR test results within the L-SCC. METHODS: The development of EVEST involved 148 participants, including 49 healthy volunteers (28 female and 21 male) and 99 (58 female and 41 male) patients affected by different degrees of peripheral vestibular deficit. The corresponding L-SCC VOR test results, from patients meeting the diagnostic criteria, were used to create the EVEST. RESULTS: Based on the test results, we depicted and calculated the EVEST vestibular function asymmetry (VFA) in all the groups. To assess a feasibility of EVEST to describe a vestibular function deficit, we calculated sensitivity and specificity of VFA using a receiver operating characteristic curve (ROC) and compared it to single tests. In all the tests, we determined the cutoff value as the point with the highest sensitivity and specificity. For discrimination of any vestibular deficit, the VFA with cutoff 6.5% was more sensitive (91%) and specific (98%) than single tests. Results showed that EVEST is a beneficial graphic tool for quick multifrequency comparison and diagnosis of different types of the peripheral vestibular loss. CONCLUSIONS: EVEST can help to easily evaluate various types of peripheral vestibular lesion.
BACKGROUND: The availability and development of methods testing the vestibuloocular reflex (VOR) brought a broader view into the lateral semicircular canal (L-SCC) function. However, the higher number of evaluated parameters makes more difficult the specialist's diagnose-making process. PURPOSE: To provide medical specialists, a new diagnostic-graphic tool, Estimated Vestibulogram- EVEST, enabling a quick and easy-to-read visualization and comparison of the VOR test results within the L-SCC. METHODS: The development of EVEST involved 148 participants, including 49 healthy volunteers (28 female and 21 male) and 99 (58 female and 41 male) patients affected by different degrees of peripheral vestibular deficit. The corresponding L-SCC VOR test results, from patients meeting the diagnostic criteria, were used to create the EVEST. RESULTS: Based on the test results, we depicted and calculated the EVEST vestibular function asymmetry (VFA) in all the groups. To assess a feasibility of EVEST to describe a vestibular function deficit, we calculated sensitivity and specificity of VFA using a receiver operating characteristic curve (ROC) and compared it to single tests. In all the tests, we determined the cutoff value as the point with the highest sensitivity and specificity. For discrimination of any vestibular deficit, the VFA with cutoff 6.5% was more sensitive (91%) and specific (98%) than single tests. Results showed that EVEST is a beneficial graphic tool for quick multifrequency comparison and diagnosis of different types of the peripheral vestibular loss. CONCLUSIONS: EVEST can help to easily evaluate various types of peripheral vestibular lesion.
Authors: David E Newman-Toker; Kevin A Kerber; Yu-Hsiang Hsieh; John H Pula; Rodney Omron; Ali S Saber Tehrani; Georgios Mantokoudis; Daniel F Hanley; David S Zee; Jorge C Kattah Journal: Acad Emerg Med Date: 2013-10 Impact factor: 3.451
Authors: Scott D Z Eggers; Alexandre Bisdorff; Michael von Brevern; David S Zee; Ji-Soo Kim; Nicolas Perez-Fernandez; Miriam S Welgampola; Charles C Della Santina; David E Newman-Toker Journal: J Vestib Res Date: 2019 Impact factor: 2.354
Authors: Maja Striteska; Martin Valis; Viktor Chrobok; Oliver Profant; Luigi Califano; Jaroslav Syba; Katerina Trnkova; Jan Kremlacek; Martin Chovanec Journal: Front Neurol Date: 2022-09-20 Impact factor: 4.086