| Literature DB >> 33762785 |
Thomas H Mader1, C Robert Gibson2,3, Michael R Barratt4, Neil R Miller5, Prem S Subramanian6, Hanspeter E Killer7, William J Tarver8, Ashot E Sargsyan3, Kathleen Garcia3, Stephen F Hart8, Larry A Kramer9, Roy Riascos9, Tyson J Brunstetter10, William Lipsky2, Peter Wostyn11, Andrew G Lee12,13,14,15,16,17,18.
Abstract
Posterior globe flattening has been well-documented in astronauts both during and after long-duration space flight (LDSF) and has been observed as early as 10 days into a mission on the International Space Station. Globe flattening (GF) is thought to be caused by the disc centred anterior forces created by elevated volume and/or pressure within the optic nerve sheath (ONS). This might be the result of increased intracranial pressure, increased intraorbital ONS pressure from compartmentalisation or a combination of these mechanisms. We report posterior GF in three astronauts that has persisted for 7 years or more following their return from LDSFs suggesting that permanent scleral remodelling may have occurred.Entities:
Keywords: SANS; astronaut; hyperopic shift; international space station (ISS); long-duration space flight (LDSF); visual changes
Year: 2020 PMID： 33762785 PMCID： PMC7946045 DOI： 10.1080/01658107.2020.1791189
Source DB: PubMed Journal: Neuroophthalmology ISSN： 0165-8107