Literature DB >> 33761600

Nrf2 a molecular therapeutic target for Astaxanthin.

Zeynab Kohandel1, Tahereh Farkhondeh2, Michael Aschner3, Saeed Samarghandian4.   

Abstract

Astaxanthin (ATX) is a red pigment carotenoid present in shrimp, salmon, crab, and asteroidean. Several studies have corroborated the anti-oxidant efficacy of ATX. In addition, ATX has anti-inflammatory, anti-apoptotic and anti-proliferative properties. In the present review, we discuss the role of Nrf2 in mediating the anti-cancer, anti-aging, neuroprotective, lung-protective, skin-protective, cardioprotective, hepatoprotective, anti-diabetic and muscloprotective effects of ATX.
Copyright © 2021. Published by Elsevier Masson SAS.

Entities:  

Keywords:  Astaxanthin; Inflammation; Nrf2; Oxidative stress

Mesh：

Substances：

Year:  2021        PMID： 33761600     DOI： 10.1016/j.biopha.2021.111374

Source DB:  PubMed          Journal:  Biomed Pharmacother        ISSN： 0753-3322            Impact factor:   6.529


  12 in total

Review 1.  Role of Phytochemicals in Skin Photoprotection via Regulation of Nrf2.

Authors:  Anyamanee Chaiprasongsuk; Uraiwan Panich
Journal:  Front Pharmacol       Date:  2022-05-12       Impact factor: 5.988

2.  Randomized controlled trial of astaxanthin impacts on antioxidant status and assisted reproductive technology outcomes in women with polycystic ovarian syndrome.

Authors:  Roghaye Gharaei; Ashraf Alyasin; Forough Mahdavinezhad; Esmaeil Samadian; Zhaleh Ashrafnezhad; Fardin Amidi
Journal:  J Assist Reprod Genet       Date:  2022-03-03       Impact factor: 3.357

Review 3.  Nrf2 Signaling Pathway in Chemoprotection and Doxorubicin Resistance: Potential Application in Drug Discovery.

Authors:  Sepideh Mirzaei; Ali Zarrabi; Farid Hashemi; Amirhossein Zabolian; Hossein Saleki; Negar Azami; Soodeh Hamzehlou; Mahdi Vasheghani Farahani; Kiavash Hushmandi; Milad Ashrafizadeh; Haroon Khan; Alan Prem Kumar
Journal:  Antioxidants (Basel)       Date:  2021-02-26

Review 4.  Astaxanthin as a Novel Mitochondrial Regulator: A New Aspect of Carotenoids, beyond Antioxidants.

Authors:  Yasuhiro Nishida; Allah Nawaz; Karen Hecht; Kazuyuki Tobe
Journal:  Nutrients       Date:  2021-12-27       Impact factor: 5.717

5.  Antioxidant effects of astaxanthin and metformin combined therapy in type 2 diabetes mellitus patients: a randomized double-blind controlled clinical trial.

Authors:  Nikoo Roustaei Rad; Ahmad Movahedian; Awat Feizi; Ashraf Aminorroaya; Mohammad Hosein Aarabi
Journal:  Res Pharm Sci       Date:  2022-01-15

Review 6.  Carotenoids: Dietary Sources, Extraction, Encapsulation, Bioavailability, and Health Benefits-A Review of Recent Advancements.

Authors:  Ramesh Kumar Saini; Parchuri Prasad; Veeresh Lokesh; Xiaomin Shang; Juhyun Shin; Young-Soo Keum; Ji-Ho Lee
Journal:  Antioxidants (Basel)       Date:  2022-04-18

Review 7.  The Use of Antioxidants as Potential Co-Adjuvants to Treat Chronic Chagas Disease.

Authors:  Edio Maldonado; Diego A Rojas; Fabiola Urbina; Aldo Solari
Journal:  Antioxidants (Basel)       Date:  2021-06-25

Review 8.  Maintaining Effective Beta Cell Function in the Face of Metabolic Syndrome-Associated Glucolipotoxicity-Nutraceutical Options.

Authors:  Mark F McCarty; James J DiNicolantonio
Journal:  Healthcare (Basel)       Date:  2021-12-21

Review 9.  Astaxanthin as a Modulator of Nrf2, NF-κB, and Their Crosstalk: Molecular Mechanisms and Possible Clinical Applications.

Authors:  Sergio Davinelli; Luciano Saso; Floriana D'Angeli; Vittorio Calabrese; Mariano Intrieri; Giovanni Scapagnini
Journal:  Molecules       Date:  2022-01-14       Impact factor: 4.411

10.  Glucosinolates and their hydrolysis products as potential nutraceuticals to combat cytokine storm in SARS-COV-2.

Authors:  Saba Rahimi Bahoosh; Yalda Shokoohinia; Mahdieh Eftekhari
Journal:  Daru       Date:  2022-02-02       Impact factor: 4.088
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