Literature DB >> 33761159

Female cancer survivors are more likely to be at high risk of malnutrition and meet the threshold for clinical importance for a number of quality of life subscales.

Laura Keaver1, Niamh O'Callaghan1, Aoibheann O'Sullivan1, Laoise Quinn1, Amy Loftus1, Catherine M McHugh2.   

Abstract

BACKGROUND: The present study aimed to explore malnutrition risk, handgrip strength and quality of life (QOL) in cancer survivors.
METHODS: In total, 232 individuals completed a demographic questionnaire, Patient-Generated Subjective Global Assessment Short Form and the European Organization for Research and Treatment of Cancer QOL Questionnaire (EORTC QLQ-C30). Handgrip strength was determined using a spring-loaded handgrip dynamometer and anthropometric measurements were taken by an oncology nurse. Frequencies and distribution data, analysis of variance and chi-squared tests were then conducted.
RESULTS: The majority of the cohort were female (n = 141; 60.8%) had breast cancer (n = 62; 26.7%) and the mean ± SD body mass index (BMI) was 26.6 ± 6.2 kg m-2 . Less than a one-third reported seeing a dietitian (n = 68; 29.3%). Over one-third reported recent weight loss (n = 88; 37.3%). Some 40.9% (n = 95) were at moderate to high risk of malnutrition, with women more likely than men to be classified as high risk (p < 0.05). Mean ± SD handgrip strength was 25 ± 15 kg and this differed significantly by gender (p = 0.00), cancer type (p = 0.01) and BMI classification (p = 0.01). One-fifth of individuals were classified as having dynapenia (n = 48; 21.1%). Median (interquartile range) QOL score was 66.7 (33.3). The proportion of individuals meeting the threshold for clinical importance for QOL subscales ranged from 12.5% (constipation) to 42.7% (physical functioning). Females were more likely than males to meet the threshold for physical functioning (p = 0.00), fatigue (p = 0.02) and pain (p = 0.01).
CONCLUSIONS: Females are more likely than males to be at high risk of malnutrition and meet the threshold for clinical significance for several QOL subscales.
© 2021 The British Dietetic Association Ltd.

Entities:  

Keywords:  cancer patient; cancer survivor; dynapenia; malnutrition; oncology care; quality of life

Mesh:

Year:  2021        PMID: 33761159     DOI: 10.1111/jhn.12877

Source DB:  PubMed          Journal:  J Hum Nutr Diet        ISSN: 0952-3871            Impact factor:   3.089


  1 in total

1.  Global leaders malnutrition initiative-defined malnutrition affects long-term survival of different subgroups of patients with gastric cancer: A propensity score-matched analysis.

Authors:  Wentao Cai; Hui Yang; Jingwei Zheng; Jianqiang Huang; Weiping Ji; Yangbin Lu; Xinxin Yang; Weiteng Zhang; Xian Shen; Xiaodong Chen
Journal:  Front Nutr       Date:  2022-09-30
  1 in total

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