Matthew J Kielt1,2,3, J Wells Logan4,5,6, Carl H Backes5,6,7,8,9, Kristina M Reber4,5,6, Leif D Nelin4,5,6,7, Edward G Shepherd4,5,6. 1. Comprehensive Center for Bronchopulmonary Dysplasia, Nationwide Children's Hospital, Columbus, OH, USA. matthew.kielt@nationwidechildrens.org. 2. Division of Neonatology, Nationwide Children's Hospital, Columbus, OH, USA. matthew.kielt@nationwidechildrens.org. 3. Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA. matthew.kielt@nationwidechildrens.org. 4. Comprehensive Center for Bronchopulmonary Dysplasia, Nationwide Children's Hospital, Columbus, OH, USA. 5. Division of Neonatology, Nationwide Children's Hospital, Columbus, OH, USA. 6. Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA. 7. Center for Perinatal Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA. 8. The Heart Center, Nationwide Children's Hospital, Columbus, OH, USA. 9. Department of Obstetrics and Gynecology, The Ohio State University, Columbus, OH, USA.
Abstract
OBJECTIVE: To determine the in-hospital outcomes for patients with established bronchopulmonary dysplasia (BPD) referred late for severe disease. STUDY DESIGN: Retrospective cohort study of patients with established BPD referred to our center after 36 weeks PMA. RESULT: Among 71 patients with BPD referred to our center after 36 weeks PMA between 2010 and 2018, the median PMA was 47 weeks (IQR, 42, 53) and the median respiratory severity score was 8.1 (IQR 4.5, 11.0) on admission. Survival in this cohort was 92%. Most survivors were discharged home without the need for positive pressure respiratory support (77%) or pulmonary vasodilators (89%). For survivors, we observed a significant improvement in median z-scores for length (-6.7 vs -3.3, p < 0.0001) between admission and discharge. CONCLUSION: Despite presenting relatively late with a high degree of illness severity, nearly all patients in this cohort survived to hospital discharge with improvement in comorbidities.
OBJECTIVE: To determine the in-hospital outcomes for patients with established bronchopulmonary dysplasia (BPD) referred late for severe disease. STUDY DESIGN: Retrospective cohort study of patients with established BPD referred to our center after 36 weeks PMA. RESULT: Among 71 patients with BPD referred to our center after 36 weeks PMA between 2010 and 2018, the median PMA was 47 weeks (IQR, 42, 53) and the median respiratory severity score was 8.1 (IQR 4.5, 11.0) on admission. Survival in this cohort was 92%. Most survivors were discharged home without the need for positive pressure respiratory support (77%) or pulmonary vasodilators (89%). For survivors, we observed a significant improvement in median z-scores for length (-6.7 vs -3.3, p < 0.0001) between admission and discharge. CONCLUSION: Despite presenting relatively late with a high degree of illness severity, nearly all patients in this cohort survived to hospital discharge with improvement in comorbidities.
Authors: Jason Gien; John Kinsella; Jodi Thrasher; Alicia Grenolds; Steven H Abman; Christopher D Baker Journal: Am J Perinatol Date: 2016-06-29 Impact factor: 1.862
Authors: Girija Natarajan; Yvette R Johnson; Beverly Brozanski; Kathryn N Farrow; Isabella Zaniletti; Michael A Padula; Jeanette M Asselin; David J Durand; Billie L Short; Eugenia K Pallotto; Francine D Dykes; Kristina M Reber; Jacquelyn R Evans; Karna Murthy Journal: Am J Perinatol Date: 2013-05-20 Impact factor: 1.862