Literature DB >> 33758027

Shock-and-kill versus block-and-lock: Targeting the fluctuating and heterogeneous HIV-1 gene expression.

Yang-Hui Jimmy Yeh1, Ya-Chi Ho2.   

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Year:  2021        PMID： 33758027      PMCID： PMC8072369          DOI： 10.1073/pnas.2103692118

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  27 in total

1.  Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity.

Authors:  Leor S Weinberger; John C Burnett; Jared E Toettcher; Adam P Arkin; David V Schaffer
Journal:  Cell       Date:  2005-07-29       Impact factor: 41.582

2.  An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription.

Authors:  Guillaume Mousseau; Mark A Clementz; Wendy N Bakeman; Nisha Nagarsheth; Michael Cameron; Jun Shi; Phil Baran; Rémi Fromentin; Nicolas Chomont; Susana T Valente
Journal:  Cell Host Microbe       Date:  2012-07-19       Impact factor: 21.023

3.  Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription.

Authors:  Tsuyoshi Hayashi; Maxime Jean; Huachao Huang; Sydney Simpson; Netty G Santoso; Jian Zhu
Journal:  Antiviral Res       Date:  2017-08-24       Impact factor: 5.970

4.  A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.

Authors:  R Brad Jones; Stefanie Mueller; Rachel O'Connor; Katherine Rimpel; Derek D Sloan; Dan Karel; Hing C Wong; Emily K Jeng; Allison S Thomas; James B Whitney; So-Yon Lim; Colin Kovacs; Erika Benko; Sara Karandish; Szu-Han Huang; Maria J Buzon; Mathias Lichterfeld; Alivelu Irrinki; Jeffrey P Murry; Angela Tsai; Helen Yu; Romas Geleziunas; Alicja Trocha; Mario A Ostrowski; Darrell J Irvine; Bruce D Walker
Journal:  PLoS Pathog       Date:  2016-04-15       Impact factor: 6.823

5.  Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.

Authors:  Alberto Bosque; Kyle A Nilson; Amanda B Macedo; Adam M Spivak; Nancie M Archin; Ryan M Van Wagoner; Laura J Martins; Camille L Novis; Matthew A Szaniawski; Chris M Ireland; David M Margolis; David H Price; Vicente Planelles
Journal:  Cell Rep       Date:  2017-01-31       Impact factor: 9.423

6.  Toll-Like Receptor 7 Agonist GS-9620 Induces HIV Expression and HIV-Specific Immunity in Cells from HIV-Infected Individuals on Suppressive Antiretroviral Therapy.

Authors:  Angela Tsai; Alivelu Irrinki; Jasmine Kaur; Tomas Cihlar; George Kukolj; Derek D Sloan; Jeffrey P Murry
Journal:  J Virol       Date:  2017-03-29       Impact factor: 5.103

7.  Screening for gene expression fluctuations reveals latency-promoting agents of HIV.

Authors:  Yiyang Lu; Kathrin Bohn-Wippert; Patrick J Pazerunas; Jennifer M Moy; Harpal Singh; Roy D Dar
Journal:  Proc Natl Acad Sci U S A       Date:  2021-03-16       Impact factor: 11.205

8.  Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation.

Authors:  Thomas Aagaard Rasmussen; Ole Schmeltz Søgaard; Christel Brinkmann; Fiona Wightman; Sharon R Lewin; Jesper Melchjorsen; Charles Dinarello; Lars Østergaard; Martin Tolstrup
Journal:  Hum Vaccin Immunother       Date:  2013-01-31       Impact factor: 3.452

9.  Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing.

Authors:  Datsen George Wei; Vicki Chiang; Elizabeth Fyne; Mini Balakrishnan; Tiffany Barnes; Michael Graupe; Joseph Hesselgesser; Alivelu Irrinki; Jeffrey P Murry; George Stepan; Kirsten M Stray; Angela Tsai; Helen Yu; Jonathan Spindler; Mary Kearney; Celsa A Spina; Deborah McMahon; Jacob Lalezari; Derek Sloan; John Mellors; Romas Geleziunas; Tomas Cihlar
Journal:  PLoS Pathog       Date:  2014-04-10       Impact factor: 6.823

10.  Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo.

Authors:  Christopher C Nixon; Maud Mavigner; Gavin C Sampey; Alyssa D Brooks; Rae Ann Spagnuolo; David M Irlbeck; Cameron Mattingly; Phong T Ho; Nils Schoof; Corinne G Cammon; Greg K Tharp; Matthew Kanke; Zhang Wang; Rachel A Cleary; Amit A Upadhyay; Chandrav De; Saintedym R Wills; Shane D Falcinelli; Cristin Galardi; Hasse Walum; Nathaniel J Schramm; Jennifer Deutsch; Jeffrey D Lifson; Christine M Fennessey; Brandon F Keele; Sherrie Jean; Sean Maguire; Baolin Liao; Edward P Browne; Robert G Ferris; Jessica H Brehm; David Favre; Thomas H Vanderford; Steven E Bosinger; Corbin D Jones; Jean-Pierre Routy; Nancie M Archin; David M Margolis; Angela Wahl; Richard M Dunham; Guido Silvestri; Ann Chahroudi; J Victor Garcia
Journal:  Nature       Date:  2020-01-22       Impact factor: 49.962
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  2 in total

Review 1.  Why the HIV Reservoir Never Runs Dry: Clonal Expansion and the Characteristics of HIV-Infected Cells Challenge Strategies to Cure and Control HIV Infection.

Authors:  Chuen-Yen Lau; Matthew A Adan; Frank Maldarelli
Journal:  Viruses       Date:  2021-12-14       Impact factor: 5.048

2.  Imaging and biopsy of HIV-infected individuals undergoing analytic treatment interruption.

Authors:  Chuen-Yen Lau; Matthew A Adan; Jessica Earhart; Cassie Seamon; Thuy Nguyen; Ariana Savramis; Lindsey Adams; Mary-Elizabeth Zipparo; Erin Madeen; Kristi Huik; Zehava Grossman; Benjamin Chimukangara; Wahyu Nawang Wulan; Corina Millo; Avindra Nath; Bryan R Smith; Ana M Ortega-Villa; Michael Proschan; Bradford J Wood; Dima A Hammoud; Frank Maldarelli
Journal:  Front Med (Lausanne)       Date:  2022-08-22
  2 in total

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