Hannah E Reese1, W Alan Brown2, Berta J Summers3,4, Jin Shin3, Grace Wheeler5, Sabine Wilhelm3. 1. Department of Psychology, Bowdoin College, 6900 College Station, Brunswick, ME, 04011, USA. hreese@bowdoin.edu. 2. Learning to Thrive, LLC, 300 2nd St., #7, Jersey City, NJ, 07302, USA. 3. Center for OCD and Related Disorders, Massachusetts General Hospital, 185 Cambridge St., Suite 2000, Boston, MA, 02114, USA. 4. Department of Psychology, University of North Carolina Wilmington, 601 South College Road, Wilmington, NC, 28403-5612, USA. 5. Department of Psychology, Bowdoin College, 6900 College Station, Brunswick, ME, 04011, USA.
Abstract
BACKGROUND: Preliminary research suggests that a mindfulness-based treatment approach may be beneficial for adults with tic disorders. In the present study, we report on the feasibility, acceptability, safety, and symptomatic effect of a novel online mindfulness-based group intervention for adults with Tourette syndrome or persistent tic disorder. Data from this study will directly inform the conduct of a funded randomized controlled trial comparing the efficacy of this intervention to another active psychological intervention. METHODS: One cohort of adults with Tourette syndrome participated in an 8-week online mindfulness-based group intervention. Measures of feasibility, acceptability, and safety were administered throughout and at posttreatment. Self-reported measures of mindfulness and clinician-rated measures of tic severity and impairment were administered at baseline and posttreatment. RESULTS: Data on refusal, dropout rate, attendance, participant satisfaction, and safety suggest that this is a feasible and acceptable intervention. However, participant adherence to home practice was lower than anticipated. Mindfulness, tic severity, and tic-related impairment only modestly improved from baseline to posttreatment. Qualitative analysis of participant feedback revealed aspects of the intervention that were most helpful and also areas for improvement. CONCLUSIONS: Data suggest that although this is a feasible and acceptable intervention, it should be modified to enhance participant adherence, more successfully engage the target mechanism, and optimize outcomes. TRIAL REGISTRATION: Clinicaltrials.gov registration # NCT03525626 . Registered on 24 April 2018.
RCT Entities:
BACKGROUND: Preliminary research suggests that a mindfulness-based treatment approach may be beneficial for adults with tic disorders. In the present study, we report on the feasibility, acceptability, safety, and symptomatic effect of a novel online mindfulness-based group intervention for adults with Tourette syndrome or persistent tic disorder. Data from this study will directly inform the conduct of a funded randomized controlled trial comparing the efficacy of this intervention to another active psychological intervention. METHODS: One cohort of adults with Tourette syndrome participated in an 8-week online mindfulness-based group intervention. Measures of feasibility, acceptability, and safety were administered throughout and at posttreatment. Self-reported measures of mindfulness and clinician-rated measures of tic severity and impairment were administered at baseline and posttreatment. RESULTS: Data on refusal, dropout rate, attendance, participant satisfaction, and safety suggest that this is a feasible and acceptable intervention. However, participant adherence to home practice was lower than anticipated. Mindfulness, tic severity, and tic-related impairment only modestly improved from baseline to posttreatment. Qualitative analysis of participant feedback revealed aspects of the intervention that were most helpful and also areas for improvement. CONCLUSIONS: Data suggest that although this is a feasible and acceptable intervention, it should be modified to enhance participant adherence, more successfully engage the target mechanism, and optimize outcomes. TRIAL REGISTRATION: Clinicaltrials.gov registration # NCT03525626 . Registered on 24 April 2018.
Entities:
Keywords:
Group treatment; Mindfulness; Online; Tic disorder; Tourette syndrome; Treatment
Authors: Thomas Steeves; B Duncan McKinlay; Daniel Gorman; Lori Billinghurst; Lundy Day; Alan Carroll; Yves Dion; Asif Doja; Sandra Luscombe; Paul Sandor; Tamara Pringsheim Journal: Can J Psychiatry Date: 2012-03 Impact factor: 4.356
Authors: Joseph F McGuire; John Piacentini; Erin A Brennan; Adam B Lewin; Tanya K Murphy; Brent J Small; Eric A Storch Journal: J Psychiatr Res Date: 2013-12-28 Impact factor: 4.791
Authors: Lawrence Scahill; Douglas W Woods; Michael B Himle; Alan L Peterson; Sabine Wilhelm; John C Piacentini; Kevin McNaught; John T Walkup; Jonathan W Mink Journal: Mov Disord Date: 2013-05-16 Impact factor: 10.338
Authors: Hannah E Reese; Lawrence Scahill; Alan L Peterson; Katherine Crowe; Douglas W Woods; John Piacentini; John T Walkup; Sabine Wilhelm Journal: Behav Ther Date: 2013-09-21
Authors: Tamara Pringsheim; Michael S Okun; Kirsten Müller-Vahl; Davide Martino; Joseph Jankovic; Andrea E Cavanna; Douglas W Woods; Michael Robinson; Elizabeth Jarvie; Veit Roessner; Maryam Oskoui; Yolanda Holler-Managan; John Piacentini Journal: Neurology Date: 2019-05-07 Impact factor: 11.800
Authors: Kesley A Ramsey; Alessandro S De Nadai; Flint M Espil; Emily Ricketts; Jordan T Stiede; Jennifer Schild; Matthew W Specht; Douglas W Woods; Shannon Bennet; John T Walkup; Susanna Chang; John Piacentini; Joseph F McGuire Journal: Front Psychiatry Date: 2022-08-10 Impact factor: 5.435