Literature DB >> 33755151

Are B7-H3 CAR-T cells the future universal treatment for pediatric brain tumors?

Franck Bourdeaut1.   

Abstract

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Year:  2021        PMID: 33755151      PMCID: PMC8168811          DOI: 10.1093/neuonc/noab063

Source DB:  PubMed          Journal:  Neuro Oncol        ISSN: 1522-8517            Impact factor:   12.300


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  5 in total

1.  CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors.

Authors:  Johanna L Theruvath; Anandani Nellan; Sabine Heitzeneder; Robbie G Majzner; Yongzhi Cui; Christopher W Mount; Skyler P Rietberg; Miles H Linde; Peng Xu; Christopher Rota; Elena Sotillo; Louai Labanieh; Daniel W Lee; Rimas J Orentas; Dimiter S Dimitrov; Zhongyu Zhu; Brad St Croix; Alberto Delaidelli; Alla Sekunova; Ezio Bonvini; Siddhartha S Mitra; Martha M Quezado; Ravindra Majeti; Michelle Monje; Poul H B Sorensen; John M Maris; Crystal L Mackall
Journal:  Clin Cancer Res       Date:  2019-01-17       Impact factor: 12.531

2.  Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells.

Authors:  Hongwei Du; Koichi Hirabayashi; Sarah Ahn; Nancy Porterfield Kren; Stephanie Ann Montgomery; Xinhui Wang; Karthik Tiruthani; Bhalchandra Mirlekar; Daniel Michaud; Kevin Greene; Silvia Gabriela Herrera; Yang Xu; Chuang Sun; Yuhui Chen; Xingcong Ma; Cristina Rosa Ferrone; Yuliya Pylayeva-Gupta; Jen Jen Yeh; Rihe Liu; Barbara Savoldo; Soldano Ferrone; Gianpietro Dotti
Journal:  Cancer Cell       Date:  2019-02-11       Impact factor: 31.743

3.  Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.

Authors:  Johanna Theruvath; Elena Sotillo; Christopher W Mount; Claus Moritz Graef; Alberto Delaidelli; Sabine Heitzeneder; Louai Labanieh; Shaurya Dhingra; Amaury Leruste; Robbie G Majzner; Peng Xu; Sabine Mueller; Derek W Yecies; Martina A Finetti; Daniel Williamson; Pascal D Johann; Marcel Kool; Stefan Pfister; Martin Hasselblatt; Michael C Frühwald; Olivier Delattre; Didier Surdez; Franck Bourdeaut; Stephanie Puget; Sakina Zaidi; Siddhartha S Mitra; Samuel Cheshier; Poul H Sorensen; Michelle Monje; Crystal L Mackall
Journal:  Nat Med       Date:  2020-04-27       Impact factor: 53.440

4.  Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery.

Authors:  Dalia Haydar; Haley Houke; Jason Chiang; Zhongzhen Yi; Zelda Odé; Kenneth Caldwell; Xiaoyan Zhu; Kimberly S Mercer; Jennifer L Stripay; Timothy I Shaw; Peter Vogel; Christopher DeRenzo; Suzanne J Baker; Martine F Roussel; Stephen Gottschalk; Giedre Krenciute
Journal:  Neuro Oncol       Date:  2021-06-01       Impact factor: 12.300

5.  Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas.

Authors:  Christopher W Mount; Robbie G Majzner; Shree Sundaresh; Evan P Arnold; Meena Kadapakkam; Samuel Haile; Louai Labanieh; Esther Hulleman; Pamelyn J Woo; Skyler P Rietberg; Hannes Vogel; Michelle Monje; Crystal L Mackall
Journal:  Nat Med       Date:  2018-04-16       Impact factor: 53.440

  5 in total

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