| Literature DB >> 33754640 |
Bev John1, Simon Newstead1, Robert Heirene2, Ray Hodgson1, Gareth Roderique-Davies1.
Abstract
AIMS: Primary aim: to determine the efficacy of FAST (the Fast Alcohol Screening Test) for detecting harmful and dependent levels of alcohol use. Secondary aim: to compare the performance of the FAST to two short forms of the Alcohol Use Disorder Identification Test (AUDIT): the AUDIT-C and AUDIT-3.Entities:
Mesh:
Year: 2021 PMID: 33754640 PMCID: PMC8631061 DOI: 10.1093/alcalc/agab015
Source DB: PubMed Journal: Alcohol Alcohol ISSN: 0735-0414 Impact factor: 2.826
Distribution of participants tested and those included in inferential analysis
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| Female |
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| Female |
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| 3366 | 1309 (38.9%) | 41.63 | 13.76 | 3,356 | 1302 (38.8%) | 41.64 | 13.68 | ||
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| 288 | 158 (55.0%) | 33.90 | 14.76 | 288 | 158 (55.0%) | 33.90 | 14.76 | ||
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| 679 | 318 (46.8%) | 36.11 | 15.89 | 671 | 311 (46.3%) | 36.09 | 15.92 | ||
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| 2399 | 833 (34.7%) | 44.09 | 12.02 | 2397 | 833 (34.8%) | 44.13 | 11.96 | ||
Note: M = mean, SD = standard deviation, CS = Community Sample, A&E = Accident and Emergency, CMHT = community Mental Health & Addictions Teams.
Total AUDIT score subdivisions with associated levels of risk and suggested interventions
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| 0–7 | Abstinence/non-hazardous use | Alcohol education | ||
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| 8–15 | Medium risk/hazardous use | Simple advice & education | ||
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| 16–19 | Harmful use/possible dependence | Simple advice, brief counselling & continued monitoring | ||
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| ≥20 | Severe alcohol dependence | Specialist referral for diagnostic evaluation & treatment |
AUROC scores, sensitivity and specificity for FAST, AUDIT-C and AUDIT-3 scores contrasted against AUDIT cut-offs
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| AUROC | Sensitivity | Specificity | AUROC | Sensitivity | Specificity | AUROC | Sensitivity | Specificity | ||||||||||||
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| Score | LB | UB | (TP) % | (TN) % | Score | LB | UB | (TP) % | (TN) % | Score | LB | UB | (TP) % | (TN) % | ||||
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| ≥4 | 0.885 | 0.867 | 0.903 | 98.8 | 78.3 | 0.890 | 0.876 | 0.905 | 99.8 | 78.3 | 0.824 | 0.807 | 0.840 | 99.9 | 64.8 | ||||
| ≥5 |
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| 0.932 | 0.921 | 0.944 | 98.6 | 87.9 | 0.869 | 0.855 | 0.884 | 99.6 | 74.2 | |||||
| ≥6 | 0.874 | 0.844 | 0.904 | 80.8 | 94.0 |
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| 0.899 | 0.887 | 0.912 | 99.0 | 80.9 | |||||
| ≥7 | 0.782 | 0.742 | 0.821 | 59.2 | 97.2 | 0.952 | 0.944 | 0.961 | 93.3 | 97.2 |
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| ≥8 | 0.681 | 0.638 | 0.725 | 36.7 | 99.6 | 0.938 | 0.929 | 0.946 | 88.0 | 99.6 | 0.923 | 0.927 | 0.947 | 94.2 | 93.2 | |||||
| ≥9 | 0.567 | 0.533 | 0.619 | 15.4 | 99.7 | 0.898 | 0.887 | 0.908 | 79.8 | 99.7 | 0.932 | 0.913 | 0.933 | 87.6 | 97.1 | |||||
| ≥10 | 0.513 | 0.472 | 0.553 | 2.5 | 100 | 0.857 | 0.845 | 0.869 | 71.4 | 100 | 0.897 | 0.885 | 0.908 | 79.8 | 99.6 | |||||
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| ≥5 | 0.768 | 0.743 | 0.793 | 100 | 53.6 | 0.768 | 0.748 | 0.787 | 100 | 53.6 | 0.721 | 0.702 | 0.740 | 99.9 | 44.2 | ||||
| ≥6 | 0.805 | 0.781 | 0.828 | 98.3 | 62.6 | 0.812 | 0.794 | 0.830 | 99.7 | 62.6 | 0.759 | 0.741 | 0.777 | 99.9 | 51.9 | |||||
| ≥7 | 0.837 | 0.813 | 0.861 | 95.0 | 72.4 | 0.857 | 0.841 | 0.874 | 99.1 | 72.4 | 0.801 | 0.784 | 0.818 | 99.6 | 60.6 | |||||
| ≥8 |
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| 0.895 | 0.881 | 0.909 | 97.4 | 81.6 | 0.843 | 0.828 | 0.858 | 98.8 | 69.8 | |||||
| ≥9 | 0.806 | 0.771 | 0.841 | 72.9 | 88.3 |
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| ≥10 | 0.764 | 0.725 | 0.803 | 59.6 | 93.2 | 0.914 | 0.903 | 0.925 | 89.6 | 93.2 | 0.886 | 0.873 | 0.899 | 79.8 | 99.6 | |||||
| ≥11 | 0.690 | 0.648 | 0.733 | 42.1 | 96.0 | 0.884 | 0.872 | 0.896 | 0.874 | 0.861 | 0.887 | 70.5 | 99.8 | |||||||
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| ≥1 | 0.703 | 0.674 | 0.732 | 91.2 | 41.4 | 0.704 | 0.683 | 0.724 | 0.669 | 0.649 | 0.688 | ||||||||
| ≥2 |
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| 0.829 | 0.812 | 0.812 | 98.8 | 67.1 | 0.777 | 0.760 | 0.795 | 99.2 | 56.2 | |||||
| ≥3 | .805 | .773 | .838 | 78.3 | 82.7 |
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| =4 | 0.693 | 0.650 | 0.736 | 42.5 | 96.1 | 0.879 | 0.867 | 0.867 | 79.8 | 96.1 | 0.868 | 0.855 | 0.881 | 84.3 | 89.3 | |||||
Note: AUDIT = Alcohol Use Disorder Identification Test, AUROC = Area Under Receiver Operating Characteristic Curve, LB = 95% confidence interval: lower bound, UB = 95% confidence interval: upper bound, = suggested cut off for harmful alcohol use, * = suggested cut off for dependent alcohol use.
Figure 1.ROC curve for the FAST, AUDIT-C and AUDIT-3, for AUDIT cut-offs for harmful and dependent alcohol use; * denotes suggested cut-off scores for AUDIT short forms.
Mean and standard deviation of scores* for the AUDIT and AUDIT short forms
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| M | SD | M | SD | |||
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| 20.94 | 12.48 | 20.98 | 12.47 | |||
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| 8.20 | 5.36 | 8.20 | 5.35 | |||
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| 8.93 | 4.01 | 8.94 | 1.50 | |||
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| 2.85 | 1.50 | 2.86 | 4.01 | |||
Note: M = mean, SD = standard deviation, AUDIT = Alcohol Use Disorder Identification Test, * = collated datasets.
Scores displayed as a percentage of the total potential available scores for each measure
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| FAST | AUDIT-C | AUDIT-3 | ||
| ≥1 | 6.25 | 8.33 | 25.00 | ||
| ≥2 | 12.50 | 16.67 |
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| ≥3 | 18.75 | 25.00 |
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| ≥4 | 25.00 | 33.33 | 100.00 | ||
| ≥5 |
| 41.67 | |||
| ≥6 | 37.50 | 50.00 | |||
| ≥7 |
| 58.33 | |||
| ≥8 | 50.00 |
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| ≥9 | 56.25 |
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| ≥10 | 62.50 | 83.30 | |||
| ≥11 | 68.75 | 91.63 | |||
Note: AUDIT = Alcohol Use Disorder Identification Test, = suggested cut off for harmful alcohol use, * = suggested cut off for dependent alcohol use. Full AUDIT Tier 3 cut off (≥16 = 40% PTS). Full AUDIT Tier 4 cut off (≥20 = 50% PTS).