Literature DB >> 33751442

Alteration of Flavin Cofactor Homeostasis in Human Neuromuscular Pathologies.

Maria Tolomeo1, Alessia Nisco1, Maria Barile2.   

Abstract

The aim of this short review chapter is to provide a brief summary of the relevance of riboflavin (Rf or vitamin B2) and its derived cofactors flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) for human neuromuscular bioenergetics.Therefore, as a completion of this book we would like to summarize what kind of human pathologies could derive from genetic disturbances of Rf transport, flavin cofactor synthesis and delivery to nascent apoflavoproteins, as well as by alteration of vitamin recycling during protein turnover.

Entities:  

Keywords:  FLAD1; LSMFLAD; MADD; RREI; RTD; SLC52As; mitochondrial flavoproteome; riboflavin

Mesh：

Substances：

Year:  2021        PMID： 33751442     DOI： 10.1007/978-1-0716-1286-6_18

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  73 in total

Review 1.  Riboflavin transport and metabolism in humans.

Authors:  Maria Barile; Teresa Anna Giancaspero; Piero Leone; Michele Galluccio; Cesare Indiveri
Journal:  J Inherit Metab Dis       Date:  2016-06-06       Impact factor: 4.982

Review 2.  Riboflavin deficiency is associated with selective preservation of critical flavoenzyme-dependent metabolic pathways.

Authors:  N S Ross; T P Hansen
Journal:  Biofactors       Date:  1992-01       Impact factor: 6.113

Review 3.  Succinate dehydrogenase - Assembly, regulation and role in human disease.

Authors:  Jared Rutter; Dennis R Winge; Joshua D Schiffman
Journal:  Mitochondrion       Date:  2010-03-10       Impact factor: 4.160

4.  Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain.

Authors:  Yoshiaki Yao; Atsushi Yonezawa; Hiroki Yoshimatsu; Satohiro Masuda; Toshiya Katsura; Ken-Ichi Inui
Journal:  J Nutr       Date:  2010-05-12       Impact factor: 4.798

5.  Three cysteine residues of SLC52A1, a receptor for the porcine endogenous retrovirus-A (PERV-A), play a critical role in cell surface expression and infectivity.

Authors:  Winston Colon-Moran; Takele Argaw; Carolyn A Wilson
Journal:  Virology       Date:  2017-04-21       Impact factor: 3.616

Review 6.  Disorders of riboflavin metabolism.

Authors:  Shanti Balasubramaniam; John Christodoulou; Shamima Rahman
Journal:  J Inherit Metab Dis       Date:  2019-03-11       Impact factor: 4.982

7.  Identification and functional characterization of rat riboflavin transporter 2.

Authors:  Syunsuke Yamamoto; Katsuhisa Inoue; Kin-ya Ohta; Rui Fukatsu; Jun-ya Maeda; Yukihiro Yoshida; Hiroaki Yuasa
Journal:  J Biochem       Date:  2009-01-03       Impact factor: 3.387

8.  Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1.

Authors:  Atsushi Yonezawa; Satohiro Masuda; Toshiya Katsura; Ken-ichi Inui
Journal:  Am J Physiol Cell Physiol       Date:  2008-07-16       Impact factor: 4.249

9.  The unassembled flavoprotein subunits of human and bacterial complex II have impaired catalytic activity and generate only minor amounts of ROS.

Authors:  Elena Maklashina; Sany Rajagukguk; T M Iverson; Gary Cecchini
Journal:  J Biol Chem       Date:  2018-04-02       Impact factor: 5.157

Review 10.  An update on the genetics, clinical presentation, and pathomechanisms of human riboflavin transporter deficiency.

Authors:  Benjamin O'Callaghan; Annet M Bosch; Henry Houlden
Journal:  J Inherit Metab Dis       Date:  2019-02-21       Impact factor: 4.982
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  4 in total

Review 1.  Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire.

Authors:  Parimala Narne; Prakash Babu Phanithi
Journal:  Cell Mol Neurobiol       Date:  2022-09-30       Impact factor: 4.231

2.  Mimicking human riboflavin responsive neuromuscular disorders by silencing flad-1 gene in C. elegans: Alteration of vitamin transport and cholinergic transmission.

Authors:  Piero Leone; Maria Tolomeo; Elisabetta Piancone; Pier Giorgio Puzzovio; Carla De Giorgi; Cesare Indiveri; Elia Di Schiavi; Maria Barile
Journal:  IUBMB Life       Date:  2021-09-24       Impact factor: 4.709

Review 3.  New Insights into the Neurodegeneration Mechanisms Underlying Riboflavin Transporter Deficiency (RTD): Involvement of Energy Dysmetabolism and Cytoskeletal Derangement.

Authors:  Fiorella Colasuonno; Chiara Marioli; Marco Tartaglia; Enrico Bertini; Claudia Compagnucci; Sandra Moreno
Journal:  Biomedicines       Date:  2022-06-06

Review 4.  Nutrients to Improve Mitochondrial Function to Reduce Brain Energy Deficit and Oxidative Stress in Migraine.

Authors:  Michal Fila; Cezary Chojnacki; Jan Chojnacki; Janusz Blasiak
Journal:  Nutrients       Date:  2021-12-10       Impact factor: 5.717
  4 in total

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