| Literature DB >> 33751416 |
Tatiane Fonseca Faro1, Allan Vinícius Martins-de-Barros1, Gilberto Tenório Wanderley Fernandes Lima2, André Pereira Raposo3, Mariana de Albuquerque Borges4, Fábio Andrey da Costa Araújo1, Marianne de Vasconcelos Carvalho1, Emerson Filipe de Carvalho Nogueira1, José Rodrigues Laureano Filho5.
Abstract
The purpose of this systematic review was to summarize the available data on TMJ chondrosarcomas and to perform a survival analysis of cases reported to date. This review was conducted in accordance with the PRISMA. Two authors performed an electronic search of case reports of TMJ chondrosarcoma published until August 02, 2020. Forty-seven studies reporting 53 cases were included. Chondrosarcomas of the TMJ were more prevalent in women, with a male:female ratio of 1:1.4. Survival curves were significantly associated with histological diagnosis (p = 0.004), reconstructive surgery (p = 0.024), recurrence (p < 0.001), and distant metastasis (p = 0.001). Only distant metastasis was independently associated with survival (p = 0.017). TMJ chondrosarcomas presented with low recurrence and higher survival rates than other chondrosarcomas. Synovial subtype, absence of reconstructive surgery, and presence of local recurrence or distant metastasis were associated with poorer prognosis.Entities:
Keywords: Chondrosarcoma; Facial neoplasms; Head and neck neoplasms; Survival Analysis; Temporomandibular joint; Temporomandibular joint disorders
Mesh：
Year: 2021 PMID： 33751416 PMCID： PMC8384949 DOI： 10.1007/s12105-021-01313-9
Source DB: PubMed Journal: Head Neck Pathol ISSN： 1936-055X