Literature DB >> 3375138

Effect of vasoactive intestinal peptide on dopaminergic system in the rat brain.

S Itoh1, G Katsuura, A Takashima.   

Abstract

The present study analyzed the effect of vasoactive intestinal peptide (VIP) on the content of dopamine (DA) and its main metabolite, DOPAC, in the rat brain. Intracerebroventricular administration of VIP increased the DA and DOPAC content, causing a dose-dependent increase in the DOPAC/DA ratio in various regions of the brain. The results suggest that VIP facilitates the DA metabolism in the brain.

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Year:  1988        PMID: 3375138     DOI: 10.1016/0196-9781(88)90266-5

Source DB:  PubMed          Journal:  Peptides        ISSN: 0196-9781            Impact factor:   3.750


  1 in total

1.  Vasoactive intestinal peptide (VIP) mediates the effect of estrogens on the dopaminergic tone in the hypothalamic-pituitary axis of ovariectomized (OVX) rats.

Authors:  M Lasaga; A Seilicovich; D Pisera; M C Díaz; M F Befumo; B H Duvilanski
Journal:  Endocrine       Date:  1997-02       Impact factor: 3.633

  1 in total

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