Literature DB >> 33748924

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2.

Weijian Hang1, Chen Chen1, Xin A Zhang2, Dao Wen Wang3.   

Abstract

The COVID-19 pandemic has caused numerous deaths around the world. A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is emerging. In addition to affecting the lungs, COVID-19 can be a severe systemic inflammatory disease that is related to endothelial dysfunction. We are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing the pathogenic mechanism of COVID-19 but also for properly adjusting the strategy of clinical intervention.
© 2021. Higher Education Press.

Entities:  

Keywords:  COVID-19; cytokine storm; endothelial dysfunction; inflammation reaction

Mesh:

Year:  2021        PMID: 33748924      PMCID: PMC7982315          DOI: 10.1007/s11684-021-0831-z

Source DB:  PubMed          Journal:  Front Med        ISSN: 2095-0217            Impact factor:   9.927


  29 in total

1.  Toll-Like Receptor-3 Mediates HIV-1-Induced Interleukin-6 Expression in the Human Brain Endothelium via TAK1 and JNK Pathways: Implications for Viral Neuropathogenesis.

Authors:  Biju Bhargavan; Georgette D Kanmogne
Journal:  Mol Neurobiol       Date:  2017-11-11       Impact factor: 5.590

2.  [A pathological report of three COVID-19 cases by minimal invasive autopsies].

Authors:  X H Yao; T Y Li; Z C He; Y F Ping; H W Liu; S C Yu; H M Mou; L H Wang; H R Zhang; W J Fu; T Luo; F Liu; Q N Guo; C Chen; H L Xiao; H T Guo; S Lin; D F Xiang; Y Shi; G Q Pan; Q R Li; X Huang; Y Cui; X Z Liu; W Tang; P F Pan; X Q Huang; Y Q Ding; X W Bian
Journal:  Zhonghua Bing Li Xue Za Zhi       Date:  2020-05-08

Review 3.  Extrapulmonary manifestations of COVID-19.

Authors:  Aakriti Gupta; Mahesh V Madhavan; Kartik Sehgal; Nandini Nair; Shiwani Mahajan; Tejasav S Sehrawat; Behnood Bikdeli; Neha Ahluwalia; John C Ausiello; Elaine Y Wan; Daniel E Freedberg; Ajay J Kirtane; Sahil A Parikh; Mathew S Maurer; Anna S Nordvig; Domenico Accili; Joan M Bathon; Sumit Mohan; Kenneth A Bauer; Martin B Leon; Harlan M Krumholz; Nir Uriel; Mandeep R Mehra; Mitchell S V Elkind; Gregg W Stone; Allan Schwartz; David D Ho; John P Bilezikian; Donald W Landry
Journal:  Nat Med       Date:  2020-07-10       Impact factor: 53.440

4.  Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study.

Authors:  George Goshua; Alexander B Pine; Matthew L Meizlish; C-Hong Chang; Hanming Zhang; Parveen Bahel; Audrey Baluha; Noffar Bar; Robert D Bona; Adrienne J Burns; Charles S Dela Cruz; Anne Dumont; Stephanie Halene; John Hwa; Jonathan Koff; Hope Menninger; Natalia Neparidze; Christina Price; Jonathan M Siner; Christopher Tormey; Henry M Rinder; Hyung J Chun; Alfred I Lee
Journal:  Lancet Haematol       Date:  2020-06-30       Impact factor: 18.959

5.  Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19.

Authors:  Xiaoyan Liu; Zhe Li; Shuai Liu; Jing Sun; Zhanghua Chen; Min Jiang; Qingling Zhang; Yinghua Wei; Xin Wang; Yi-You Huang; Yinyi Shi; Yanhui Xu; Huifang Xian; Fan Bai; Changxing Ou; Bei Xiong; Andrew M Lew; Jun Cui; Rongli Fang; Hui Huang; Jincun Zhao; Xuechuan Hong; Yuxia Zhang; Fuling Zhou; Hai-Bin Luo
Journal:  Acta Pharm Sin B       Date:  2020-04-20       Impact factor: 11.413

6.  COVID-19: the vasculature unleashed.

Authors:  Laure-Anne Teuwen; Vincent Geldhof; Alessandra Pasut; Peter Carmeliet
Journal:  Nat Rev Immunol       Date:  2020-07       Impact factor: 53.106

7.  Tocilizumab, an anti-IL-6 receptor antibody, to treat COVID-19-related respiratory failure: a case report.

Authors:  J-M Michot; L Albiges; N Chaput; V Saada; F Pommeret; F Griscelli; C Balleyguier; B Besse; A Marabelle; F Netzer; M Merad; C Robert; F Barlesi; B Gachot; A Stoclin
Journal:  Ann Oncol       Date:  2020-04-02       Impact factor: 32.976

8.  Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

Authors:  Bin Zhang; Shuyi Liu; Tan Tan; Wenhui Huang; Yuhao Dong; Luyan Chen; Qiuying Chen; Lu Zhang; Qingyang Zhong; Xiaoping Zhang; Yujian Zou; Shuixing Zhang
Journal:  Chest       Date:  2020-03-31       Impact factor: 9.410

9.  Arbidol combined with LPV/r versus LPV/r alone against Corona Virus Disease 2019: A retrospective cohort study.

Authors:  Lisi Deng; Chunna Li; Qi Zeng; Xi Liu; Xinghua Li; Haitang Zhang; Zhongsi Hong; Jinyu Xia
Journal:  J Infect       Date:  2020-03-11       Impact factor: 6.072

10.  Functional exhaustion of antiviral lymphocytes in COVID-19 patients.

Authors:  Meijuan Zheng; Yong Gao; Gang Wang; Guobin Song; Siyu Liu; Dandan Sun; Yuanhong Xu; Zhigang Tian
Journal:  Cell Mol Immunol       Date:  2020-03-19       Impact factor: 11.530

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  4 in total

Review 1.  ACE-2 down-regulation may act as a transient molecular disease causing RAAS dysregulation and tissue damage in the microcirculatory environment among COVID-19 patients.

Authors:  Simone Gusmão Ramos; Bruna Amanda da Cruz Rattis; Giulia Ottaviani; Mara Rubia Nunes Celes; Eliane Pedra Dias
Journal:  Am J Pathol       Date:  2021-05-05       Impact factor: 4.307

2.  Inflammation at the crossroads of Helicobacter pylori and COVID-19.

Authors:  Ileana Gonzalez; Cristian Lindner; Ivan Schneider; Miguel A Morales; Armando Rojas
Journal:  Future Microbiol       Date:  2021-12-17       Impact factor: 3.165

Review 3.  COVID-19 in Joint Ageing and Osteoarthritis: Current Status and Perspectives.

Authors:  Marianne Lauwers; Manting Au; Shuofeng Yuan; Chunyi Wen
Journal:  Int J Mol Sci       Date:  2022-01-10       Impact factor: 5.923

4.  Inhalation Bioaccessibility of Polycyclic Aromatic Hydrocarbons in PM2.5 under Various Lung Environments: Implications for Air Pollution Control during Coronavirus Disease-19 Outbreak.

Authors:  Pengfei Zhou; Yi Kong; Xinyi Cui
Journal:  Environ Sci Technol       Date:  2022-03-25       Impact factor: 9.028

  4 in total

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