Literature DB >> 33748826

Understanding the Brain through Aging Eyes.

Marian Blazes1, Cecilia S Lee1,2.   

Abstract

The eye and brain share common mechanisms of aging and disease, thus the retina is an essential source of accessible information about neurodegenerative processes occurring in the brain. Advances in retinal imaging have led to the discovery of many potential biomarkers of Alzheimer's disease, although further research is needed to validate these associations. Understanding the mechanisms of retinal disease in the context of aging will extend our knowledge of AD and may enable advancements in diagnosis, monitoring, and treatment.

Entities:  

Keywords:  Alzheimer’s disease; dementia; retina; retinal biomarker; retinal imaging

Year:  2021        PMID: 33748826      PMCID: PMC7971450          DOI: 10.20900/agmr20210008

Source DB:  PubMed          Journal:  Adv Geriatr Med Res


  49 in total

1.  Endothelial Activation and Oxidative Stress in Neurovascular Defects of the Retina.

Authors:  Raji Lenin; Samuel M Thomas; Rajashekhar Gangaraju
Journal:  Curr Pharm Des       Date:  2018       Impact factor: 3.116

2.  Vision Impairment and Risk of Dementia: Findings from the English Longitudinal Study of Ageing.

Authors:  Hilary R Davies-Kershaw; Ruth A Hackett; Dorina Cadar; Annie Herbert; Martin Orrell; Andrew Steptoe
Journal:  J Am Geriatr Soc       Date:  2018-08-11       Impact factor: 5.562

3.  Retinal fluorescence lifetime imaging ophthalmoscopy measures depend on the severity of Alzheimer's disease.

Authors:  Susanne Jentsch; Dietrich Schweitzer; Kai-Uwe Schmidtke; Sven Peters; Jens Dawczynski; Karl-Jürgen Bär; Martin Hammer
Journal:  Acta Ophthalmol       Date:  2014-12-07       Impact factor: 3.761

4.  Early age-related macular degeneration, cognitive function, and dementia: the Cardiovascular Health Study.

Authors:  Michelle L Baker; Jie Jin Wang; Sophie Rogers; Ronald Klein; Lewis H Kuller; Emily K Larsen; Tien Yin Wong
Journal:  Arch Ophthalmol       Date:  2009-05

Review 5.  Connecting the retina to the brain.

Authors:  Lynda Erskine; Eloisa Herrera
Journal:  ASN Neuro       Date:  2014-12-12       Impact factor: 4.146

6.  Change in retinal structural anatomy during the preclinical stage of Alzheimer's disease.

Authors:  Cláudia Y Santos; Lenworth N Johnson; Stuart E Sinoff; Elena K Festa; William C Heindel; Peter J Snyder
Journal:  Alzheimers Dement (Amst)       Date:  2018-02-07

Review 7.  Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances.

Authors:  Wenzhang Wang; Fanpeng Zhao; Xiaopin Ma; George Perry; Xiongwei Zhu
Journal:  Mol Neurodegener       Date:  2020-05-29       Impact factor: 14.195

8.  Retinal oxygen metabolism in patients with mild cognitive impairment.

Authors:  Olof Birna Olafsdottir; Hrafnhildur Sif Saevarsdottir; Sveinn Hakon Hardarson; Kristin Hanna Hannesdottir; Valgerdur Dora Traustadottir; Robert Arnar Karlsson; Anna Bryndis Einarsdottir; Katrin Dilja Jonsdottir; Einar Stefansson; Jon Snaedal
Journal:  Alzheimers Dement (Amst)       Date:  2018-04-01

9.  Correlation Between Diabetic Cognitive Impairment and Diabetic Retinopathy in Patients With T2DM by 1H-MRS.

Authors:  Xuefang Lu; Wei Gong; Zhi Wen; Lanhua Hu; Zhoufeng Peng; Yunfei Zha
Journal:  Front Neurol       Date:  2019-11-12       Impact factor: 4.003

10.  Ganglion cell layer thinning in prodromal Alzheimer's disease defined by amyloid PET.

Authors:  Alicia López-de-Eguileta; Carmen Lage; Sara López-García; Ana Pozueta; María García-Martínez; Martha Kazimierczak; María Bravo; María de Arcocha-Torres; Ignacio Banzo; Julio Jimenez-Bonilla; Andrea Cerveró; Eloy Rodríguez-Rodríguez; Pascual Sánchez-Juan; Alfonso Casado
Journal:  Alzheimers Dement (N Y)       Date:  2019-10-09
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  3 in total

1.  Understanding How Sensory Changes Experienced by Individuals with a Range of Age-Related Cognitive Changes Can Effect Technology Use.

Authors:  Emma Dixon; Jesse Anderson; Amanda Lazar
Journal:  ACM Trans Access Comput       Date:  2022

2.  Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain.

Authors:  Aimée Parker; Stefano Romano; Rebecca Ansorge; Asmaa Aboelnour; Gwenaelle Le Gall; George M Savva; Matthew G Pontifex; Andrea Telatin; David Baker; Emily Jones; David Vauzour; Steven Rudder; L Ashley Blackshaw; Glen Jeffery; Simon R Carding
Journal:  Microbiome       Date:  2022-04-29       Impact factor: 16.837

3.  Risk factors for cognitive decline in type 2 diabetes mellitus patients in Brazil: a prospective observational study.

Authors:  Ana Cristina Ravazzani de Almeida Faria; Joceline Franco Dall'Agnol; Aline Maciel Gouveia; Clara Inácio de Paiva; Victoria Chechetto Segalla; Cristina Pellegrino Baena
Journal:  Diabetol Metab Syndr       Date:  2022-07-27       Impact factor: 5.395

  3 in total

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