| Literature DB >> 33747450 |
Humaira Hussain1, Feroza Hamid Wattoo1, Muhammad Hamid Sarwar Wattoo2, Muhammad Gulfraz1, Tariq Masud3, Imam Shah4, Sakhawat Ali4, Seyed Ebrahim Alavi5.
Abstract
Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its unique composition helps to regulate the blood glucose level. The current study is aimed to evaluate the antidiabetic and hepatoprotective effects, as well as lipid profile restoration of camel milk in the diabetic mouse model. This innovative study evaluates the therapeutic effects of camel milk in diabetic mice by simultaneous measurement of blood glucose, HbA1c, ALT, AST, TG, cholesterol, and histopathological studies. The results showed that camel milk has significantly reduced blood glucose, HbA1c (p < .001), aspartate transaminase (AST), alanine transaminase (ALT) (p < .01), triglyceride (TG), and cholesterol (p < .01), compared to that in the diabetic control group. Also, the therapeutic effects of camel milk were completely comparable with the antidiabetic drug glibenclamide. The results of this study suggest that camel milk could be used as a proper alternative treatment regimen for diabetes therapy.Entities:
Keywords: antidiabetic activity; glibenclamide; hepatoprotective effect; triglyceride
Year: 2021 PMID: 33747450 PMCID: PMC7958562 DOI: 10.1002/fsn3.2078
Source DB: PubMed Journal: Food Sci Nutr ISSN: 2048-7177 Impact factor: 2.863