Zakariya Bambala Puthattayil1, Thuy Mai Luu2, Marc Beltempo3, Shannon Cross4, Thevanisha Pillay5, Marilyn Ballantyne6, Anne Synnes7, Prakesh Shah8, Thierry Daboval1. 1. Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario. 2. Department of Pediatrics, CHU Sainte-Justine, Montreal, Quebec. 3. Department of Pediatrics, Montreal Children's Hospital - McGill University Health Centre, Montreal, Quebec. 4. Perinatal and NICU Services, Victoria General Hospital, Victoria, British Columbia. 5. Department of Pediatrics, Victoria General Hospital, Victoria, British Columbia. 6. Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario. 7. Department of Pediatrics, Children's & Women's Health Centre of British Columbia, Vancouver, British Columbia. 8. Department of Pediatrics, Mount Sinai Hospital, Toronto, Ontario.
Abstract
OBJECTIVE: Survivors of extremely preterm birth are at risk of re-hospitalization but risk factors in the Canadian population are unknown. Our objective is to identify neonatal, sociodemographic, and geographic characteristics that predict re-hospitalization in Canadian extremely preterm neonates. METHODS: This is a retrospective analysis of a prospective observational cohort study that included preterm infants born 22 to 28 weeks' gestational age from April 1, 2009 to September 30, 2011 and seen at 18 to 24 months corrected gestational age in a Canadian Neonatal Follow-Up Network clinic. Characteristics of infants re-hospitalized versus not re-hospitalized are compared. The potential neonatal, sociodemographic, and geographic factors with significant association in the univariate analysis are included in a multivariate model. RESULTS: From a total of 2,275 preterm infants born at 22 to 28 weeks gestation included, 838 (36.8%) were re-hospitalized at least once. There were significant disparities between Canadian provincial regions, ranging from 25.9% to 49.4%. In the multivariate logistic regression analysis, factors associated with an increased risk for re-hospitalization were region of residence, male sex, bronchopulmonary dysplasia, necrotizing enterocolitis, prolonged neonatal intensive care unit (NICU) stay, ethnicity, Indigenous ethnicity, and sibling(s) in the home. CONCLUSION: Various neonatal, sociodemographic, and geographic factors predict re-hospitalization of extremely preterm infants born in Canada. The risk factors of re-hospitalization provide insights to help health care leaders explore potential preventative approaches to improve child health and reduce health care system costs.
OBJECTIVE: Survivors of extremely preterm birth are at risk of re-hospitalization but risk factors in the Canadian population are unknown. Our objective is to identify neonatal, sociodemographic, and geographic characteristics that predict re-hospitalization in Canadian extremely preterm neonates. METHODS: This is a retrospective analysis of a prospective observational cohort study that included preterm infants born 22 to 28 weeks' gestational age from April 1, 2009 to September 30, 2011 and seen at 18 to 24 months corrected gestational age in a Canadian Neonatal Follow-Up Network clinic. Characteristics of infants re-hospitalized versus not re-hospitalized are compared. The potential neonatal, sociodemographic, and geographic factors with significant association in the univariate analysis are included in a multivariate model. RESULTS: From a total of 2,275 preterm infants born at 22 to 28 weeks gestation included, 838 (36.8%) were re-hospitalized at least once. There were significant disparities between Canadian provincial regions, ranging from 25.9% to 49.4%. In the multivariate logistic regression analysis, factors associated with an increased risk for re-hospitalization were region of residence, male sex, bronchopulmonary dysplasia, necrotizing enterocolitis, prolonged neonatal intensive care unit (NICU) stay, ethnicity, Indigenous ethnicity, and sibling(s) in the home. CONCLUSION: Various neonatal, sociodemographic, and geographic factors predict re-hospitalization of extremely preterm infants born in Canada. The risk factors of re-hospitalization provide insights to help health care leaders explore potential preventative approaches to improve child health and reduce health care system costs.
Authors: M S Kramer; R W Platt; S W Wen; K S Joseph; A Allen; M Abrahamowicz; B Blondel; G Bréart Journal: Pediatrics Date: 2001-08 Impact factor: 7.124
Authors: Ricardo A Mosquera; Elenir B C Avritscher; Cheryl L Samuels; Tomika S Harris; Claudia Pedroza; Patricia Evans; Fernando Navarro; Susan H Wootton; Susan Pacheco; Guy Clifton; Shade Moody; Luisa Franzini; John Zupancic; Jon E Tyson Journal: JAMA Date: 2014 Dec 24-31 Impact factor: 56.272
Authors: Sarka Lisonkova; Matthew D Haslam; Leanne Dahlgren; Innie Chen; Anne R Synnes; Kenneth I Lim Journal: CMAJ Date: 2016-09-26 Impact factor: 8.262