Literature DB >> 33743394

A computational study of the hemodynamics of bioprosthetic aortic valves with reduced leaflet motion.

Shantanu Bailoor1, Jung-Hee Seo1, Lakshmi Prasad Dasi2, Stefano Schena3, Rajat Mittal4.   

Abstract

We employ a reduced degree-of-freedom aortic valve model to investigate the flow physics associated with early-stage reduced leaflet motion in bioprosthetic aortic valves. The model is coupled with a sharp-interface immersed boundary based incompressible flow solver to efficiently simulate the fluid-structure interaction. A total of 19 cases of flow through aortic valves with varying degrees of reduced leaflet motion (RLM) are considered. The characteristics of the aortic jet and the consequent aorta wall loading patterns are analyzed. Our results show that asymmetric RLM tilts the aortic jet and leads to large reverse and recirculating flow regions downstream from leaflets with restricted mobility. The changes in flow patterns increase wall pressure and shear stress fluctuations, and result in asymmetric oscillating shear on the aorta wall. These findings have implications for auscultation based diagnosis of this condition as well as the health of the aorta.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Keywords:  Fluid structure interaction; Immersed boundary method; Leaflet thrombosis; Reduced-order models; Transcatheter aortic valves

Year:  2021        PMID: 33743394     DOI: 10.1016/j.jbiomech.2021.110350

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  2 in total

1.  Computational Modeling of Drug Dissolution in the Human Stomach.

Authors:  Jung Hee Seo; Rajat Mittal
Journal:  Front Physiol       Date:  2022-01-10       Impact factor: 4.566

2.  Characterization of Turbulent Flow Behind a Transcatheter Aortic Valve in Different Implantation Positions.

Authors:  Leonardo Pietrasanta; Shaokai Zheng; Dario De Marinis; David Hasler; Dominik Obrist
Journal:  Front Cardiovasc Med       Date:  2022-01-13
  2 in total

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