| Literature DB >> 33741496 |
Arpita P Tiwari1, Nanasaheb D Thorat2, Sabrina Pricl3, Rakesh M Patil4, Sonali Rohiwal5, Helen Townley6.
Abstract
'Bioinks' are important tools for the fabrication of artificial living-tissue constructs that are able to mimic all properties of native tissues via 3D bioprinting technologies. Bioinks are most commonly made by incorporating live cells of interest within a natural or synthetic biocompatible polymeric matrix. In oncology research, the ability to recreate a tumor microenvironment (TME) using by 3D bioprinting constitutes a promising approach for drug development, screening, and in vitro cancer modeling. Here, we review the different types of bioink used for 3D bioprinting, with a focus on its application in cancer management. In addition, we consider the fabrication of bioink using customized materials/cells and their properties in the field of cancer drug discovery.Entities:
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Year: 2021 PMID: 33741496 DOI: 10.1016/j.drudis.2021.03.010
Source DB: PubMed Journal: Drug Discov Today ISSN: 1359-6446 Impact factor: 7.851