Peipei Han1, Yinjiao Zhao2, Peiyu Song1,3, Yuanyuan Zhang3, Liyan Wang3, Zhuoying Tao1, Zhengxing Jiang1, Shijing Shen1, Yunxiao Wu1, Jiajie Wu1, Xiaoyu Chen3, Xing Yu1, Yong Zhao1, Qi Guo4. 1. Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, 1500 Zhouyuan Road, Pudong New District, Shanghai, 201318, China. 2. Tianjin Key Laboratory of Metabolic Cardiovascular Diseases, Key Laboratory of Immune Microenvironment and Disease-Ministry of Education, Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China. 3. Department of Rehabilitation Medicine, Tianjin Medical University, Tianjin, China. 4. Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, 1500 Zhouyuan Road, Pudong New District, Shanghai, 201318, China. guoqijp@gmail.com.
Abstract
OBJECTIVE: The purpose of this study was to examine whether muscle mass, muscle strength, and physical performance were associated with metabolic syndrome (MetS) in community-dwelling older Chinese adults. METHODS: The study comprised of 1413 community-dwelling Chinese participants (577 men; mean ± standard deviation age: 71.3 ± 5.9) recruited from Tianjin and Shanghai, China who were invited to participate in a comprehensive geriatric assessment. The International Diabetes Federation metabolic syndrome guidelines were used to define MetS, including high waist circumference, elevated blood pressure, elevated fasting blood glucose, elevated triglycerides, and reduced HDL cholesterol. Muscle mass was measured by appendicular skeletal muscle mass/weight (ASM/weight), and ASM was measured by BIA. Muscle strength was measured using grip strength. Physical performance was represented by walking speed and the time up and go test (TUGT). RESULTS: The overall prevalence of MetS was 46.8% (34.1% in males and 55.5% in females). In the final logistic regression model, there was a significant, graded inverse association between muscle mass and MetS (p for trend = 0.014). Muscle strength and physical performance, including walking speed and TUGT, were not associated with overall MetS. In the components of MetS, muscle mass and grip strength were significantly inversely associated with high waist circumference and elevated blood pressure (p < 0.05), while physical performance was not associated with components of MetS. CONCLUSIONS: Compared with muscle strength and muscle function, muscle mass was inversely associated with MetS in a community-dwelling elderly Chinese population. Among muscle mass、muscle strength and physical performance, muscle mass appears to have the strongest association with MetS in the elderly.
OBJECTIVE: The purpose of this study was to examine whether muscle mass, muscle strength, and physical performance were associated with metabolic syndrome (MetS) in community-dwelling older Chinese adults. METHODS: The study comprised of 1413 community-dwelling Chinese participants (577 men; mean ± standard deviation age: 71.3 ± 5.9) recruited from Tianjin and Shanghai, China who were invited to participate in a comprehensive geriatric assessment. The International Diabetes Federation metabolic syndrome guidelines were used to define MetS, including high waist circumference, elevated blood pressure, elevated fasting blood glucose, elevated triglycerides, and reduced HDL cholesterol. Muscle mass was measured by appendicular skeletal muscle mass/weight (ASM/weight), and ASM was measured by BIA. Muscle strength was measured using grip strength. Physical performance was represented by walking speed and the time up and go test (TUGT). RESULTS: The overall prevalence of MetS was 46.8% (34.1% in males and 55.5% in females). In the final logistic regression model, there was a significant, graded inverse association between muscle mass and MetS (p for trend = 0.014). Muscle strength and physical performance, including walking speed and TUGT, were not associated with overall MetS. In the components of MetS, muscle mass and grip strength were significantly inversely associated with high waist circumference and elevated blood pressure (p < 0.05), while physical performance was not associated with components of MetS. CONCLUSIONS: Compared with muscle strength and muscle function, muscle mass was inversely associated with MetS in a community-dwelling elderly Chinese population. Among muscle mass、muscle strength and physical performance, muscle mass appears to have the strongest association with MetS in the elderly.
Authors: Anda Botoseneanu; Walter T Ambrosius; Daniel P Beavers; Nathalie de Rekeneire; Stephen Anton; Timothy Church; Sara C Folta; Bret H Goodpaster; Abby C King; Barbara J Nicklas; Bonnie Spring; Xuewen Wang; Thomas M Gill Journal: J Am Geriatr Soc Date: 2015-01-30 Impact factor: 5.562
Authors: Soo Lim; Jung Hee Kim; Ji Won Yoon; Seon Mee Kang; Sung Hee Choi; Young Joo Park; Ki Woong Kim; Jae Young Lim; Kyong Soo Park; Hak Chul Jang Journal: Diabetes Care Date: 2010-05-11 Impact factor: 19.112
Authors: Kristen M Beavers; Fang-Chi Hsu; Denise K Houston; Daniel P Beavers; Tamara B Harris; Trisha F Hue; Lauren J Kim; Annemarie Koster; Brenda W Penninx; Eleanor M Simonsick; Elsa S Strotmeyer; Stephen B Kritchevsky; Barbara J Nicklas Journal: J Gerontol A Biol Sci Med Sci Date: 2012-10-29 Impact factor: 6.053
Authors: Everson A Nunes; Lauren Colenso-Semple; Sean R McKellar; Thomas Yau; Muhammad Usman Ali; Donna Fitzpatrick-Lewis; Diana Sherifali; Claire Gaudichon; Daniel Tomé; Philip J Atherton; Maria Camprubi Robles; Sandra Naranjo-Modad; Michelle Braun; Francesco Landi; Stuart M Phillips Journal: J Cachexia Sarcopenia Muscle Date: 2022-02-20 Impact factor: 12.910