| Literature DB >> 33739255 |
Jamie Lopez Bernal1, Mary A Sinnathamby1, Suzanne Elgohari1, Hongxin Zhao1, Chinelo Obi1, Laura Coughlan1, Vasileios Lampos2, Ruth Simmons1, Elise Tessier1, Helen Campbell1, Suzanna McDonald1, Joanna Ellis3, Helen Hughes1, Gillian Smith1, Mark Joy4,5, Manasa Tripathy4,5, Rachel Byford4,5, Filipa Ferreira4,5, Simon de Lusignan4,5, Maria Zambon3, Gavin Dabrera6, Kevin Brown1,3, Vanessa Saliba1, Nick Andrews1, Gayatri Amirthalingam1, Sema Mandal1, Michael Edelstein1, Alex J Elliot1, Mary Ramsay1.
Abstract
BackgroundA multi-tiered surveillance system based on influenza surveillance was adopted in the United Kingdom in the early stages of the coronavirus disease (COVID-19) epidemic to monitor different stages of the disease. Mandatory social and physical distancing measures (SPDM) were introduced on 23 March 2020 to attempt to limit transmission.AimTo describe the impact of SPDM on COVID-19 activity as detected through the different surveillance systems.MethodsData from national population surveys, web-based indicators, syndromic surveillance, sentinel swabbing, respiratory outbreaks, secondary care admissions and mortality indicators from the start of the epidemic to week 18 2020 were used to identify the timing of peaks in surveillance indicators relative to the introduction of SPDM. This timing was compared with median time from symptom onset to different stages of illness and levels of care or interactions with healthcare services.ResultsThe impact of SPDM was detected within 1 week through population surveys, web search indicators and sentinel swabbing reported by onset date. There were detectable impacts on syndromic surveillance indicators for difficulty breathing, influenza-like illness and COVID-19 coding at 2, 7 and 12 days respectively, hospitalisations and critical care admissions (both 12 days), laboratory positivity (14 days), deaths (17 days) and nursing home outbreaks (4 weeks).ConclusionThe impact of SPDM on COVID-19 activity was detectable within 1 week through community surveillance indicators, highlighting their importance in early detection of changes in activity. Community swabbing surveillance may be increasingly important as a specific indicator, should circulation of seasonal respiratory viruses increase.Entities:
Keywords: COVID-19; coronavirus; lockdown; non-pharmaceutical interventions; social distancing; surveillance
Mesh:
Year: 2021 PMID: 33739255 PMCID: PMC7976385 DOI: 10.2807/1560-7917.ES.2021.26.11.2001062
Source DB: PubMed Journal: Euro Surveill ISSN: 1025-496X