Literature DB >> 33735318

Elicitation of stakeholder viewpoints about medical cannabis research for pain management in critically ill ventilated patients: A Q-methodology study.

Giulio DiDiodato1,2, Samah Hassan3, Kieran Cooley3,4,5.   

Abstract

OBJECTIVES: To determine acceptability of medical cannabis research in critically ill patients.
DESIGN: Q-methodology survey.
SETTING: Convenience sample of healthcare providers and the general public were recruited at an acute care community hospital in Ontario, Canada. PARTICIPANTS: In the first phase, 63 respondents provided 197 unique viewpoints in response to a topic statement about medical cannabis use in critically ill patients. Twenty-five viewpoints were selected for the q-sample. In the second phase, 99 respondents ranked these viewpoints according to an a priori quasi normal distribution ranging from +4 (most agree) to -4 (least agree). Factor analysis was combined with comments provided by survey respondents to label and describe the extracted factors.
RESULTS: The factor labels were hoping and caring (factor 1), pragmatic progress (factor 2), and cautious/conservative and protectionist (factor 3). Factor 1 describes a viewpoint of unequivocal support for medical cannabis research in this population with few caveats. Factor 2 describes a viewpoint of cautious support with a need to monitor for unintended adverse effects. Factor 3 describes a viewpoint of ensuring that current analgosedation techniques are optimized before exposing patients to another potentially harmful drug.
CONCLUSIONS: Using a q-methodology design, we were able to sample and describe the viewpoints that exist about medical cannabis research in critically ill patients. Three factors emerged that seemed to adequately describe the relative ranking of q-statements by the majority of respondents. Combining the distinguishing statements along with respondent comments allowed us to determine that the majority support medical cannabis research in critically ill patients.

Entities:  

Year:  2021        PMID: 33735318      PMCID: PMC7971896          DOI: 10.1371/journal.pone.0248475

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  16 in total

1.  Addressing the Psychological Symptoms of Critical Illness: The Importance of "Negative" Trials in Guiding Next Steps.

Authors:  Erin K Kross; Kathryn I Pollak; J Randall Curtis
Journal:  JAMA       Date:  2019-02-19       Impact factor: 56.272

2.  WHO proposes rescheduling cannabis to allow medical applications.

Authors:  Susan Mayor
Journal:  BMJ       Date:  2019-02-05

Review 3.  Opioid Tolerance in Critical Illness.

Authors:  J A Jeevendra Martyn; Jianren Mao; Edward A Bittner
Journal:  N Engl J Med       Date:  2019-01-24       Impact factor: 91.245

Review 4.  Current evidence of cannabinoid-based analgesia obtained in preclinical and human experimental settings.

Authors:  J Lötsch; I Weyer-Menkhoff; I Tegeder
Journal:  Eur J Pain       Date:  2017-11-21       Impact factor: 3.931

5.  Risks and Benefits of Marijuana Use: A National Survey of U.S. Adults.

Authors:  Salomeh Keyhani; Stacey Steigerwald; Julie Ishida; Marzieh Vali; Magdalena Cerdá; Deborah Hasin; Camille Dollinger; Sodahm R Yoo; Beth E Cohen
Journal:  Ann Intern Med       Date:  2018-07-24       Impact factor: 25.391

6.  Public opinion and medical cannabis policies: examining the role of underlying beliefs and national medical cannabis policies.

Authors:  Sharon R Sznitman; Anne Line Bretteville-Jensen
Journal:  Harm Reduct J       Date:  2015-10-14

7.  Knowledge and attitudes of Australian general practitioners towards medicinal cannabis: a cross-sectional survey.

Authors:  Emily A Karanges; Anastasia Suraev; Natalie Elias; Ramesh Manocha; Iain S McGregor
Journal:  BMJ Open       Date:  2018-07-03       Impact factor: 2.692

Review 8.  Therapeutic potential of medicinal marijuana: an educational primer for health care professionals.

Authors:  Yara Mouhamed; Andrey Vishnyakov; Bessi Qorri; Manpreet Sambi; Sm Signy Frank; Catherine Nowierski; Anmol Lamba; Umrao Bhatti; Myron R Szewczuk
Journal:  Drug Healthc Patient Saf       Date:  2018-06-11

9.  Genetic components of human pain sensitivity: a protocol for a genome-wide association study of experimental pain in healthy volunteers.

Authors:  Annina B Schmid; Kaustubh Adhikari; Luis Miguel Ramirez-Aristeguieta; Juan-Camilo Chacón-Duque; Giovanni Poletti; Carla Gallo; Francisco Rothhammer; Gabriel Bedoya; Andres Ruiz-Linares; David L Bennett
Journal:  BMJ Open       Date:  2019-04-20       Impact factor: 2.692

10.  The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study.

Authors:  Marta Di Forti; Diego Quattrone; Tom P Freeman; Giada Tripoli; Charlotte Gayer-Anderson; Harriet Quigley; Victoria Rodriguez; Hannah E Jongsma; Laura Ferraro; Caterina La Cascia; Daniele La Barbera; Ilaria Tarricone; Domenico Berardi; Andrei Szöke; Celso Arango; Andrea Tortelli; Eva Velthorst; Miguel Bernardo; Cristina Marta Del-Ben; Paulo Rossi Menezes; Jean-Paul Selten; Peter B Jones; James B Kirkbride; Bart Pf Rutten; Lieuwe de Haan; Pak C Sham; Jim van Os; Cathryn M Lewis; Michael Lynskey; Craig Morgan; Robin M Murray
Journal:  Lancet Psychiatry       Date:  2019-03-19       Impact factor: 77.056

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