Literature DB >> 3373480

Design, synthesis, and antineoplastic activity of 2'-deoxy-2'-methylidenecytidine.

K Takenuki1, A Matsuda, T Ueda, T Sasaki, A Fujii, K Yamagami.   

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Year:  1988        PMID: 3373480     DOI: 10.1021/jm00401a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  6 in total

Review 1.  Clinical pharmacokinetics of 2'-deoxy-2'-methylidenecytidine (DMDC), a deoxycytidine analogue antineoplastic agent.

Authors:  C J Brindley; R Morrison; R J Gordon; A J Devlin; A van der Gaast; L Verweij; T Funaki
Journal:  Clin Pharmacokinet       Date:  2000-06       Impact factor: 6.447

Review 2.  Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present.

Authors:  Sarah E Huff; Jordan M Winter; Chris G Dealwis
Journal:  Biomolecules       Date:  2022-06-10

3.  Superresolution imaging of individual replication forks reveals unexpected prodrug resistance mechanism.

Authors:  Therese Triemer; Alessandra Messikommer; Stella M K Glasauer; Jawad Alzeer; Miriam H Paulisch; Nathan W Luedtke
Journal:  Proc Natl Acad Sci U S A       Date:  2018-01-29       Impact factor: 11.205

4.  Deletion mutants of human deoxycytidine kinase mRNA in cells resistant to antitumor cytosine nucleosides.

Authors:  T Obata; Y Endo; M Tanaka; H Uchida; A Matsuda; T Sasaki
Journal:  Jpn J Cancer Res       Date:  2001-07

5.  Antitumor activity and pharmacokinetics of TAS-106, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine.

Authors:  Y Shimamoto; A Fujioka; H Kazuno; Y Murakami; H Ohshimo; T Kato; A Matsuda; T Sasaki; M Fukushima
Journal:  Jpn J Cancer Res       Date:  2001-03

6.  Branched-chain C-cyano pyranonucleosides: synthesis of 3'-C-cyano & 3'-C-cyano-3'-deoxy pyrimidine pyranonucleosides as novel cytotoxic agents.

Authors:  Christos Kiritsis; Stella Manta; Vanessa Parmenopoulou; Jan Balzarini; Dimitri Komiotis
Journal:  Eur J Med Chem       Date:  2011-09-01       Impact factor: 6.514

  6 in total

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