| Literature DB >> 33734040 |
Hakan Erdem1, Sally Hargreaves2, Handan Ankarali3, Hulya Caskurlu4, Sevil Alkan Ceviker5, Asiye Bahar-Kacmaz6, Meliha Meric-Koc1, Mustafa Altindis7, Yasemin Yildiz-Kirazaldi8, Filiz Kizilates9, Jameela Alsalman10, Yasemin Cag2, Abu Hena Mostafa Kamal11, Ilyas Dokmetas12, Emine Kubra Dindar-Demiray13, Ghaydaa Ahmed Shehata14, Hakan Hasman15, Ainur Sadykova16, Ferran Llopis17, Ergys Ramosaco18, Mateja Logar19, Handan Alay20, Fatma Kesmez-Can20, Yvon Ruch21, Dilek Bulut22, Mateja Jankovic Makek23, Andrea Marino24, Amjad Mahboob25, Amani El-Kholy26, Dirar Abdallah27, Merve Sefa-Sayar22, Ridvan Karaali28, Selda Aslan29, Razi Even Dar30, Esam Abdalla31, Helena Monzón-Camps32, Rusmir Baljić33, Dumitru Irina Mgdalena34, Behrouz Naghili35, Mohamed Elhassan Abbas Dafalla36, Ameen S S Alwashmi37, Cernat Roxana Carmen38, Sergio Ramirez-Estrada39, Marzena Wojewodzka-Zelezniakowicz40, Ozay Akyildiz41, Joanna Zajkowska40, Rehab El-Sokkary42, Nirav Pandya43, Fatma Amer44, Ilad Alavi-Darazam45, Svjetlana Grgić46, Ahmed Ashraf Wegdan47, Jehan El-Kholy48, Cansu Bulut-Avsar49, Sholpan Kulzhanova50, Meltem Tasbakan49, Hema Prakash Kumari51, Natalia Dirani52, Kalyan Koganti53, Aidos K Konkayev54, Michael M Petrov55, Antonio Cascio56, Anna Liskova57, Rosa Fontana Del Vecchio58, Lorenza Lambertenghi59, Nikolay Mladenov60, Serkan Oncu61, Jordi Rello62,63,64.
Abstract
We aimed to explore factors for optimizing antimicrobial treatment in emergency departments. A single-day point prevalence survey was conducted on January 18, 2020, in 53 referral/tertiary hospitals in 22 countries. 1957 (17%) of 11557 patients presenting to EDs had infections. The mean qSOFA score was 0.37 ± 0.74. Sepsis (qSOFA ≥ 2) was recorded in 218 (11.1%) patients. The mean qSOFA score was significantly higher in low-middle (1.48 ± 0.963) compared to upper-middle (0.17 ± 0.482) and high-income (0.36 ± 0.714) countries (P < 0.001). Eight (3.7%) patients with sepsis were treated as outpatients. The most common diagnoses were upper-respiratory (n = 877, 43.3%), lower-respiratory (n = 316, 16.1%), and lower-urinary (n = 201, 10.3%) infections. 1085 (55.4%) patients received antibiotics. The most-commonly used antibiotics were beta-lactam (BL) and BL inhibitors (n = 307, 15.7%), third-generation cephalosporins (n = 251, 12.8%), and quinolones (n = 204, 10.5%). Irrational antibiotic use and inappropriate hospitalization decisions seemed possible. Patients were more septic in countries with limited resources. Hence, a better organizational scheme is required.Entities:
Keywords: Emergency; antibiotic; elderly; infection; sepsis; treatment
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Year: 2021 PMID： 33734040 DOI： 10.1080/1120009X.2020.1863696
Source DB: PubMed Journal: J Chemother ISSN： 1120-009X Impact factor: 1.714