| Literature DB >> 33732669 |
Shih-Hsing Lo1, Yi-Ching Liu1, Zen-Kong Dai1,2, I-Chen Chen1,2, Yen-Hsien Wu1, Jong-Hau Hsu1,2.
Abstract
Valsartan/sacubitril is a new agent approved for the treatment of chronic heart failure in adults, with a combination of angiotensin receptor inhibitor and neprilysin inhibitor. However, the benefit of valsartan/sacubitril in pediatric patients is unknown. We herein report its clinical benefit in a case of acute decompensated heart failure in chemotherapy-induced cardiomyopathy. This case suggests that in children with acute heart failure refractory to conventional medications, low dose of sacubitril/valsartan may be an effective therapy.Entities:
Keywords: cardiomyopathy; chemotherapy; pediatric heart failure; treatment; valsartan/sacubitril
Year: 2021 PMID: 33732669 PMCID: PMC7959725 DOI: 10.3389/fped.2021.639551
Source DB: PubMed Journal: Front Pediatr ISSN: 2296-2360 Impact factor: 3.418