Literature DB >> 33732399

Efficacy of the feed additive consisting of decoquinate (Deccox®) for use in chickens for fattening (Zoetis Belgium SA).

Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Fašmon Durjava, Maryline Kouba, Marta López-Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Jürgen Gropp, Guido Rychen, Orsolya Holczknecht, Maria Vittoria Vettori.   

Abstract

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the efficacy of decoquinate (Deccox®) for chickens for fattening. In a former opinion adopted by the FEEDAP Panel, the potential of decoquinate to prevent coccidiosis in chickens for fattening could not be established due to insufficient evidence. In the present assessment, the applicant submitted new efficacy studies in chickens for fattening to address the data gaps identified in the previous opinion. In addition, the applicant proposed to increase the minimum of the dose range from 20 mg decoquinate/kg complete feed to 30 mg/kg. The coccidiostatic efficacy of decoquinate from Deccox® in chickens for fattening was shown in three floor pen studies at a level of 30 mg decoquinate/kg complete feed. Considering the results of three anticoccidial sensitivity tests (ASTs) with 30 mg decoquinate/kg complete feed for chickens for fattening already described and assessed in a previous FEEDAP opinion and taking into account the newly submitted floor pen data with 30 mg decoquinate/kg complete feed, the FEEDAP Panel concludes that decoquinate from Deccox® is effective in controlling coccidiosis in chickens for fattening at a minimum dose of 30 mg/kg complete feed.
© 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

Entities:  

Keywords:  Deccox®; chickens for fattening; coccidiostats; decoquinate; efficacy

Year:  2021        PMID: 33732399      PMCID: PMC7938356          DOI: 10.2903/j.efsa.2021.6453

Source DB:  PubMed          Journal:  EFSA J        ISSN: 1831-4732


  4 in total

1.  Anticoccidial drugs: lesion scoring techniques in battery and floor-pen experiments with chickens.

Authors:  J Johnson; W M Reid
Journal:  Exp Parasitol       Date:  1970-08       Impact factor: 2.011

2.  Safety and efficacy of Deccox® (decoquinate) for chickens for fattening.

Authors:  Vasileios Bampidis; Giovanna Azimonti; Maria de Lourdes Bastos; Henrik Christensen; Birgit Dusemund; Maryline Kouba; Mojca Kos Durjava; Marta López-Alonso; Secundino López Puente; Francesca Marcon; Baltasar Mayo; Alena Pechová; Mariana Petkova; Fernando Ramos; Yolanda Sanz; Roberto Edoardo Villa; Ruud Woutersen; Gabriele Aquilina; Georges Bories; Pier Sandro Cocconcelli; Paul Brantom; Ingrid Halle; Boris Kolar; Patrick van Beelen; Pieter Wester; Orsolya Holczknecht; Maria Vittoria Vettori; Jürgen Gropp
Journal:  EFSA J       Date:  2019-01-14

3.  Guidance on the assessment of the efficacy of feed additives.

Authors:  Guido Rychen; Gabriele Aquilina; Giovanna Azimonti; Vasileios Bampidis; Maria de Lourdes Bastos; Georges Bories; Andrew Chesson; Pier Sandro Cocconcelli; Gerhard Flachowsky; Jürgen Gropp; Boris Kolar; Maryline Kouba; Marta López-Alonso; Secundino López Puente; Alberto Mantovani; Baltasar Mayo; Fernando Ramos; Maria Saarela; Roberto Edoardo Villa; Robert John Wallace; Pieter Wester; Montserrat Anguita; Jaume Galobart; Matteo Lorenzo Innocenti; Laura Martino
Journal:  EFSA J       Date:  2018-05-07

4.  Assessment of the feed additive consisting of endo-1,4-β-xylanase produced by Trichoderma reeseiCBS 114044 (ECONASE®XT) for piglets (weaned), chickens reared for laying, chickens for fattening, turkeys for fattening and turkeys reared for breeding for the renewal of its authorisation (Roal Oy).

Authors:  Vasileios Bampidis; Giovanna Azimonti; Maria de Lourdes Bastos; Henrik Christensen; Birgit Dusemund; Mojca Fašmon Durjava; Maryline Kouba; Marta López-Alonso; Secundino López Puente; Francesca Marcon; Baltasar Mayo; Alena Pechová; Mariana Petkova; Fernando Ramos; Yolanda Sanz; Roberto Edoardo Villa; Ruud Woutersen; Pier Sandro Cocconcelli; Boet Debora Glandorf; Lieve Herman; Miguel Prieto Maradona; Maria Saarela; Montserrat Anguita; Rosella Brozzi; Jaume Galobart; Lucilla Gregoretti; Matteo L Innocenti; Gloria López-Gálvez; Maria Vittoria Vettori; Joana Revez
Journal:  EFSA J       Date:  2021-02-23
  4 in total
  1 in total

Review 1.  Chemical and Pharmacological Properties of Decoquinate: A Review of Its Pharmaceutical Potential and Future Perspectives.

Authors:  Tainá Santos Souza; Diogo Rodrigo Magalhães Moreira; Henrique Rodrigues Marcelino
Journal:  Pharmaceutics       Date:  2022-06-30       Impact factor: 6.525

  1 in total

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