Literature DB >> 33731003

Acute cannabis intoxication in the emergency department: the effect of legalization.

Robert Baraniecki1,2,3, Puru Panchal4, Danya Deepsee Malhotra4, Alexandra Aliferis4, Zaka Zia4.   

Abstract

BACKGROUND: On October 17, 2018, the Cannabis Act decriminalized the recreational use of cannabis in Canada. This study seeks to determine how legalization of cannabis has impacted emergency department (ED) visits for acute cannabis intoxication.
METHODS: We conducted a retrospective chart review at an academic ED in Hamilton, Ontario. We assessed all visits with a cannabis-related ICD-10 discharge code 6 months before and after legalization (October 17, 2018) to determine cases of acute cannabis intoxication. The primary outcome was the rate of ED visits. Secondary outcomes included number of visits distributed by age, length of stay, co-ingestions, and clinical course in the emergency department (investigations and treatment).
RESULTS: There was no difference in the overall rate of ED visits following legalization (2.44 vs. 2.94 visits/1000, p = 0.27). However, we noted a 56% increase in visits among adults aged 18-29 (p = 0.03). Following legalization, a larger portion of patients required observation without interventions (25% vs 48%, p < 0.05). Bloodwork and imaging studies decreased (53% vs. 12%, p < 0.05; 29% vs. 2%, p < 0.05); however, treatment with benzodiazepines increased (24% vs. 51%, p < 0.05).
CONCLUSIONS: Legalization was not associated with a change in the rate of cannabis-related ED visits in our study. More research is needed regarding changing methods of cannabis ingestion and trends among specific age groups.

Entities:  

Keywords:  Cannabis; Emergency; Health policy; Toxicology

Year:  2021        PMID: 33731003      PMCID: PMC7968301          DOI: 10.1186/s12873-021-00428-0

Source DB:  PubMed          Journal:  BMC Emerg Med        ISSN: 1471-227X


  11 in total

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Review 3.  Pharmacology and effects of cannabis: a brief review.

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4.  Colorado Cannabis Legalization and Its Effect on Emergency Care.

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5.  Sociodemographic and drug use severity differences between medical marijuana users and non-medical users visiting the emergency department.

Authors:  Susan I Woodruff; Audrey M Shillington
Journal:  Am J Addict       Date:  2016-06-21

Review 6.  The pharmacologic and clinical effects of medical cannabis.

Authors:  Laura M Borgelt; Kari L Franson; Abraham M Nussbaum; George S Wang
Journal:  Pharmacotherapy       Date:  2013-02       Impact factor: 4.705

7.  Pediatric marijuana exposures in a medical marijuana state.

Authors:  George Sam Wang; Genie Roosevelt; Kennon Heard
Journal:  JAMA Pediatr       Date:  2013-07       Impact factor: 16.193

Review 8.  Adverse health effects of marijuana use.

Authors:  Nora D Volkow; Ruben D Baler; Wilson M Compton; Susan R B Weiss
Journal:  N Engl J Med       Date:  2014-06-05       Impact factor: 91.245

9.  The Effect of Perceived Risk on the Combined Used of Alcohol and Marijuana: Results from Daily Surveys.

Authors:  Gloria Yeomans-Maldonado; Megan E Patrick
Journal:  Addict Behav Rep       Date:  2015-12-01

Review 10.  Legalized Cannabis in Colorado Emergency Departments: A Cautionary Review of Negative Health and Safety Effects.

Authors:  Brad A Roberts
Journal:  West J Emerg Med       Date:  2019-06-03
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  3 in total

1.  Impact of marijuana legalization on cannabis-related visits to the emergency department.

Authors:  Nicole V Tolan; Tolumofe Terebo; Peter R Chai; Timothy B Erickson; Bryan D Hayes; Sacha N Uljon; Athena K Petrides; Christiana A Demetriou; Stacy E F Melanson
Journal:  Clin Toxicol (Phila)       Date:  2021-12-22       Impact factor: 4.467

Review 2.  Cannabinoid hyperemesis syndrome and cannabis withdrawal syndrome: a review of the management of cannabis-related syndrome in the emergency department.

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Review 3.  The impact of cannabis legalization for recreational purposes on youth: A narrative review of the Canadian experience.

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  3 in total

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