Davide Allegrini1,2, Giovanni Montesano3,4, Stefania Marconi5, Nicoletta Rosso6, Giovanni Ometto3,4, Raffaele Raimondi1, Ferdinando Auricchio5, Panagiotis Tsoutsanis1, Francesco Semeraro7, Matteo Cacciatori6, David P Crabb3, Mario R Romano1,2. 1. Department of Biomedical Sciences, Humanitas University, Milan, Italy. 2. Department of Ophthalmology, Humanitas Gavazzeni-Castelli, Bergamo, Italy. 3. City, University of London-Optometry and Visual Sciences, London, United Kingdom. 4. NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL, Institute of Ophthalmology, London, United Kingdom. 5. Department of Civil Engineering and Architecture, University of Pavia, Pavia, Italy. 6. Ophthalmology Service, Istituti Ospitalieri di Cremona, Cremona, Italy. 7. Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, Eye Clinic, University of Brescia, Brescia, Italy.
Abstract
PURPOSE: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. METHODS: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery. RESULTS: Best-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline. CONCLUSION: While all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction.
PURPOSE: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. METHODS: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery. RESULTS: Best-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline. CONCLUSION: While all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction.
Authors: Ching Hui Ng; Ning Cheung; Jie Jin Wang; Amirul F M Islam; Ryo Kawasaki; Stacy M Meuer; Mary Frances Cotch; Barbara E K Klein; Ronald Klein; Tien Yin Wong Journal: Ophthalmology Date: 2010-10-29 Impact factor: 12.079
Authors: Giovanni Ometto; Ismail Moghul; Giovanni Montesano; Andrew Hunter; Nikolas Pontikos; Pete R Jones; Pearse A Keane; Xiaoxuan Liu; Alastair K Denniston; David P Crabb Journal: Transl Vis Sci Technol Date: 2019-05-29 Impact factor: 3.283
Authors: Sunil K Parapuram; Binyue Chang; Lei Li; Ren A Hartung; Kakarla V Chalam; Joyce U Nair-Menon; D Margaret Hunt; Richard C Hunt Journal: Invest Ophthalmol Vis Sci Date: 2009-07-02 Impact factor: 4.799