Literature DB >> 33729613

Synaptic dysfunction in amyotrophic lateral sclerosis/frontotemporal dementia: Therapeutic strategies and novel biomarkers.

Karthik Krishnamurthy1, Piera Pasinelli1.   

Abstract

Entities:  

Keywords:  FUS; TDP-43; biomarker; frontotemporal dementia; liquid-liquid phase separation; motor neuron disease/amyotrophic lateral sclerosis; protein aggregation; stress granules; synaptic dysfunction; synaptotagmin

Mesh：

Substances：

Year:  2021        PMID： 33729613      PMCID： PMC8085061          DOI： 10.1002/jnr.24824

Source DB:  PubMed          Journal:  J Neurosci Res        ISSN： 0360-4012            Impact factor:   4.433


× No keyword cloud information.
  39 in total

Review 1.  The molecular language of membraneless organelles.

Authors:  Edward Gomes; James Shorter
Journal:  J Biol Chem       Date:  2018-07-25       Impact factor: 5.157

2.  Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity.

Authors:  Menglong Zeng; Yuan Shang; Yoichi Araki; Tingfeng Guo; Richard L Huganir; Mingjie Zhang
Journal:  Cell       Date:  2016-08-25       Impact factor: 41.582

3.  Synaptotagmin 13: structure and expression of a novel synaptotagmin.

Authors:  C von Poser; T C Südhof
Journal:  Eur J Cell Biol       Date:  2001-01       Impact factor: 4.492

Review 4.  Towards an Understanding of Synapse Formation.

Authors:  Thomas C Südhof
Journal:  Neuron       Date:  2018-10-24       Impact factor: 17.173

5.  Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS.

Authors:  Gary A B Armstrong; Pierre Drapeau
Journal:  Hum Mol Genet       Date:  2013-06-13       Impact factor: 6.150

Review 6.  Stress granules as crucibles of ALS pathogenesis.

Authors:  Yun R Li; Oliver D King; James Shorter; Aaron D Gitler
Journal:  J Cell Biol       Date:  2013-04-29       Impact factor: 10.539

7.  Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization.

Authors:  Florence Rage; Nawal Boulisfane; Khalil Rihan; Henry Neel; Thierry Gostan; Edouard Bertrand; Rémy Bordonné; Johann Soret
Journal:  RNA       Date:  2013-10-23       Impact factor: 4.942

8.  Amyotrophic lateral sclerosis mutant TDP-43 may cause synaptic dysfunction through altered dendritic spine function.

Authors:  Tongcui Jiang; Emily Handley; Mariana Brizuela; Edgar Dawkins; Katherine E A Lewis; Rosemary M Clark; Tracey C Dickson; Catherine A Blizzard
Journal:  Dis Model Mech       Date:  2019-05-17       Impact factor: 5.758

9.  Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization.

Authors:  Ian Casci; Karthik Krishnamurthy; Sukhleen Kour; Vadreenath Tripathy; Nandini Ramesh; Eric N Anderson; Lara Marrone; Rogan A Grant; Stacie Oliver; Lauren Gochenaur; Krishani Patel; Jared Sterneckert; Amanda M Gleixner; Christopher J Donnelly; Marc-David Ruepp; Antonella M Sini; Emanuela Zuccaro; Maria Pennuto; Piera Pasinelli; Udai Bhan Pandey
Journal:  Nat Commun       Date:  2019-12-06       Impact factor: 14.919

10.  Synaptic Actions of Amyotrophic Lateral Sclerosis-Associated G85R-SOD1 in the Squid Giant Synapse.

Authors:  Yuyu Song
Journal:  eNeuro       Date:  2020-04-22
View more
  1 in total

Review 1.  The role of pathological tau in synaptic dysfunction in Alzheimer's diseases.

Authors:  Moxin Wu; Manqing Zhang; Xiaoping Yin; Kai Chen; Zhijian Hu; Qin Zhou; Xianming Cao; Zhiying Chen; Dan Liu
Journal:  Transl Neurodegener       Date:  2021-11-10       Impact factor: 8.014
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.