Literature DB >> 33728178

Rare Case of Multiple Intradural Extramedullary Spinal Schwannomas With Intramedullary Extension.

Gasim Ahmed1, Usman Sheikh2, Timothy Dawson3, Hemant Sonwalker2.   

Abstract

Spinal schwannomas are benign WHO grade I nerve sheath tumors that account for nearly 30% of all spinal neoplasm. Typically, these lesions are intradural extramedullary in location and are composed entirely of well-differentiated eosinophilic Schwann cells. Intramedullary schwannomas, however, are extremely rare due to the lack of Schwan cells in the normal spinal cord and represent 1% of all the spinal schwannoma population. The presence of such an intramedullary component makes diagnosis challenging as imaging features may resemble other intramedullary neoplastic entities. Here, we describe a case of a 56-year-old male patient who presented with an 18-month history of intermittent right-sided mid-thoracic pain secondary to multiple intradural extramedullary spinal schwannoma with intramedullary extensions. We also review the literature pertaining to the condition.
Copyright © 2021, Ahmed et al.

Entities:  

Keywords:  extramedullary; intradural; intramedullary extension; neuroimaging; schwannoma; spinal

Year:  2021        PMID: 33728178      PMCID: PMC7946570          DOI: 10.7759/cureus.13228

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  19 in total

Review 1.  Neuropathology for the neuroradiologist: Antoni A and Antoni B tissue patterns.

Authors:  F J Wippold; M Lubner; R J Perrin; M Lämmle; A Perry
Journal:  AJNR Am J Neuroradiol       Date:  2007-09-24       Impact factor: 3.825

2.  Preoperative diagnosis of intramedullary spinal schwannomas.

Authors:  Liang Wu; Ning Yao; Daxing Chen; Xiaofeng Deng; Yulun Xu
Journal:  Neurol Med Chir (Tokyo)       Date:  2011       Impact factor: 1.742

3.  MR imaging of a case of a dumbbell-shaped spinal schwannoma with intramedullary and intradural-extramedullary components.

Authors:  K Kono; Y Inoue; H Nakamura; M Shakudo; K Nakayama
Journal:  Neuroradiology       Date:  2001-10       Impact factor: 2.804

Review 4.  The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

Authors:  David N Louis; Arie Perry; Guido Reifenberger; Andreas von Deimling; Dominique Figarella-Branger; Webster K Cavenee; Hiroko Ohgaki; Otmar D Wiestler; Paul Kleihues; David W Ellison
Journal:  Acta Neuropathol       Date:  2016-05-09       Impact factor: 17.088

5.  Schwannomatosis, sporadic schwannomatosis, and familial schwannomatosis: a surgical series with long-term follow-up. Clinical article.

Authors:  Augusto Gonzalvo; Adam Fowler; Raymond John Cook; Nicholas Scott Little; Helen Wheeler; Kerrie L McDonald; Michael Thomas Biggs
Journal:  J Neurosurg       Date:  2010-10-08       Impact factor: 5.115

6.  Tuberculosis - 'The great masquerader' presenting as a dumb-bell-shaped intradural extramedullary tumor in a 20-year-old female.

Authors:  Mukunth Rajgopalan; Amit Srivastava; Ish K Dhammi; Anil K Jain
Journal:  J Clin Orthop Trauma       Date:  2016-06-22

Review 7.  Spinal hemangioma mimicking a dumbbell-shaped schwannoma: Case report and review of the literature.

Authors:  Kevin T Huang; Malia McAvoy; Jeffrey Helgager; Viren Vasudeva; John H Chi
Journal:  J Clin Neurosci       Date:  2018-02-02       Impact factor: 1.961

Review 8.  Magnetic resonance imaging of intramedullary spinal cord schwannomas. Report of two cases and review of the literature.

Authors:  Cesare Colosimo; Alfonso Cerase; Luca Denaro; Giulio Maira; Romano Greco
Journal:  J Neurosurg       Date:  2003-07       Impact factor: 5.115

Review 9.  Spinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature.

Authors:  Piero Conti; Gastone Pansini; Homere Mouchaty; Christian Capuano; Renato Conti
Journal:  Surg Neurol       Date:  2004-01

10.  Learning from eponyms: Jose Verocay and Verocay bodies, Antoni A and B areas, Nils Antoni and Schwannomas.

Authors:  Rajiv Joshi
Journal:  Indian Dermatol Online J       Date:  2012-09
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