Literature DB >> 33725898

Pituitary tumor apoplexy associated with extrapontine myelinolysis during pregnancy: A case report.

Wenfeng Ye1, Wenjie Huang2, Linlin Chen1, Changfang Yao1, Shiying Sheng3, Zhengyu Liu4, Chunyan Xue1, Wei Xing2.   

Abstract

RATIONALE: Pituitary tumor apoplexy (PTA) is a rare clinical syndrome which requires urgent diagnosis and treatment due to its life-threatening consequences. Management of undiagnosed pituitary tumor before pregnancy is a problem during pregnancy. PATIENT CONCERNS: We reported a case with PTA which was not diagnosed before pregnancy presenting with vomiting associated with hyponatremia during the third trimester. After supplying the sodium the patient presented with dysarthria and hemiplegia. DIAGNOSES: MRI examination showed PTA accompanied with extrapontine myelinolysis (EPM).
INTERVENTIONS: The patient was given hydrocortisone according to the symptoms gradually to taper off dose, at the same times oral levothyroxine therapy (25μg/day) was given. OUTCOMES: The patient delivered a healthy baby via cesarean section at hospital at 38 + 1 week of gestation. We performed MRI examination regularly and the tumor regressed significantly 8 months postpartum. LESSONS: We reported a case as PTA associated with EPM. Headache during pregnancy is often nonspecific, so careful medical history inquiry is very important.
Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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Year:  2021        PMID: 33725898      PMCID: PMC7969261          DOI: 10.1097/MD.0000000000025075

Source DB:  PubMed          Journal:  Medicine (Baltimore)        ISSN: 0025-7974            Impact factor:   1.817


  18 in total

1.  Prolactinomas and pregnancy.

Authors:  Mark E Molitch
Journal:  Clin Endocrinol (Oxf)       Date:  2010-06-09       Impact factor: 3.478

2.  Osmotic demyelination syndrome.

Authors:  Rachel Abbott; Eli Silber; Joerg Felber; Enefiok Ekpo
Journal:  BMJ       Date:  2005-10-08

Review 3.  Pituitary apoplexy.

Authors:  Wenya Linda Bi; Ian F Dunn; Edward R Laws
Journal:  Endocrine       Date:  2014-07-26       Impact factor: 3.633

4.  Macroprolactinomas and Nonfunctioning Pituitary Adenomas and Pregnancy Outcomes.

Authors:  Kimberley Lambert; Kate Rees; Paul T Seed; Mandish K Dhanjal; Marian Knight; David R McCance; Catherine Williamson
Journal:  Obstet Gynecol       Date:  2017-01       Impact factor: 7.661

5.  Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia. Implications for the pathogenesis of central pontine myelinolysis.

Authors:  Y H Lien; J I Shapiro; L Chan
Journal:  J Clin Invest       Date:  1991-07       Impact factor: 14.808

Review 6.  Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline.

Authors:  Shlomo Melmed; Felipe F Casanueva; Andrew R Hoffman; David L Kleinberg; Victor M Montori; Janet A Schlechte; John A H Wass
Journal:  J Clin Endocrinol Metab       Date:  2011-02       Impact factor: 5.958

7.  Classical pituitary apoplexy: clinical features, management and outcome.

Authors:  H S Randeva; J Schoebel; J Byrne; M Esiri; C B Adams; J A Wass
Journal:  Clin Endocrinol (Oxf)       Date:  1999-08       Impact factor: 3.478

Review 8.  Osmotic demyelination syndrome: central pontine myelinolysis and extrapontine myelinolysis.

Authors:  Anthony M Alleman
Journal:  Semin Ultrasound CT MR       Date:  2013-09-28       Impact factor: 1.875

Review 9.  Pituitary apoplexy: evaluation, management, and prognosis.

Authors:  Sally Murad-Kejbou; Eric Eggenberger
Journal:  Curr Opin Ophthalmol       Date:  2009-11       Impact factor: 3.761

Review 10.  Headache and pregnancy: a systematic review.

Authors:  A Negro; Z Delaruelle; T A Ivanova; S Khan; R Ornello; B Raffaelli; A Terrin; U Reuter; D D Mitsikostas
Journal:  J Headache Pain       Date:  2017-10-19       Impact factor: 7.277

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