Literature DB >> 33725172

[Ocular involvement in Stevens-Johnson syndrome and toxic epidermal necrolysis].

Argyrios Chronopoulos1, Maja Mockenhaupt2, Uwe Pleyer3.   

Abstract

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe and often life-threatening reactions of the skin and mucous membranes. They are considered as a single disease entity with different expressions of severity and are summarized under the term epidermal necrolysis (EN). There is a high risk of ocular involvement, which can lead to long-lasting eye problems and even blindness without immediate ophthalmological treatment. The acute occurrence, the unpredictable course and extreme variation in the manifestation of complications require an interdisciplinary approach. A rapid diagnosis of eye involvement and initiation of an intensive lubricating and anti-inflammatory surface treatment is of utmost importance for the long-term outcome. This article should help ophthalmologists to have a better understanding of this condition and therefore lead to substantial improvement in visual outcome and the quality of life of patients.

Entities:  

Keywords:  Anti-inflammatory treatment; Blindness; Quality of life; Severity of illness score for toxic epidermal necrolysis; Visual outcome

Year:  2021        PMID: 33725172     DOI: 10.1007/s00347-021-01351-2

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  52 in total

1.  SCORTEN: a severity-of-illness score for toxic epidermal necrolysis.

Authors:  S Bastuji-Garin; N Fouchard; M Bertocchi; J C Roujeau; J Revuz; P Wolkenstein
Journal:  J Invest Dermatol       Date:  2000-08       Impact factor: 8.551

2.  Toxic epidermal necrolysis: an eruption resembling scalding of the skin.

Authors:  A LYELL
Journal:  Br J Dermatol       Date:  1956-11       Impact factor: 9.302

3.  Late outcomes in adult survivors of toxic epidermal necrolysis after treatment in a burn center.

Authors:  Julia Haber; Wilma Hopman; Manuel Gomez; Robert Cartotto
Journal:  J Burn Care Rehabil       Date:  2005 Jan-Feb

4.  Erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis: acute ocular manifestations, causes, and management.

Authors:  Yi-Sheng Chang; Fu-Chin Huang; Sung-Huei Tseng; Chao-Kai Hsu; Chung-Liang Ho; Hamm-Ming Sheu
Journal:  Cornea       Date:  2007-02       Impact factor: 2.651

5.  Incidence of Stevens-Johnson Syndrome and Chemical Burns to the Eye.

Authors:  Michelle L White; James Chodosh; Jisun Jang; Claes Dohlman
Journal:  Cornea       Date:  2015-12       Impact factor: 2.651

Review 6.  [Acute life-threatening drug reactions of the skin].

Authors:  M Mockenhaupt
Journal:  Hautarzt       Date:  2018-05       Impact factor: 0.751

7.  Incidence of Epidermal Necrolysis: Results of the German Registry.

Authors:  David Naegele; Peggy Sekula; Maren Paulmann; Maja Mockenhaupt
Journal:  J Invest Dermatol       Date:  2020-04-28       Impact factor: 8.551

8.  Correlations between clinical patterns and causes of erythema multiforme majus, Stevens-Johnson syndrome, and toxic epidermal necrolysis: results of an international prospective study.

Authors:  Ariane Auquier-Dunant; Maja Mockenhaupt; Luigi Naldi; Osvaldo Correia; Werner Schröder; Jean-Claude Roujeau
Journal:  Arch Dermatol       Date:  2002-08

9.  Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme.

Authors:  S Bastuji-Garin; B Rzany; R S Stern; N H Shear; L Naldi; J C Roujeau
Journal:  Arch Dermatol       Date:  1993-01

Review 10.  Bullous Drug Reactions.

Authors:  Maja Mockenhaupt
Journal:  Acta Derm Venereol       Date:  2020-02-12       Impact factor: 3.875

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