| Literature DB >> 33725172 |
Argyrios Chronopoulos1, Maja Mockenhaupt2, Uwe Pleyer3.
Abstract
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe and often life-threatening reactions of the skin and mucous membranes. They are considered as a single disease entity with different expressions of severity and are summarized under the term epidermal necrolysis (EN). There is a high risk of ocular involvement, which can lead to long-lasting eye problems and even blindness without immediate ophthalmological treatment. The acute occurrence, the unpredictable course and extreme variation in the manifestation of complications require an interdisciplinary approach. A rapid diagnosis of eye involvement and initiation of an intensive lubricating and anti-inflammatory surface treatment is of utmost importance for the long-term outcome. This article should help ophthalmologists to have a better understanding of this condition and therefore lead to substantial improvement in visual outcome and the quality of life of patients.Entities:
Keywords: Anti-inflammatory treatment; Blindness; Quality of life; Severity of illness score for toxic epidermal necrolysis; Visual outcome
Year: 2021 PMID: 33725172 DOI: 10.1007/s00347-021-01351-2
Source DB: PubMed Journal: Ophthalmologe ISSN: 0941-293X Impact factor: 1.059