Literature DB >> 33724644

Presenting symptoms of COVID-19 and clinical outcomes in hospitalised older adults.

Kate Gregorevic1, Andrea Maier1,2, Roeisa Miranda1, Paula Loveland1, Katherine Miller1, Kirsty Buising3, Caroline Marshall4, Bronwyn O'Gorman1, Amanda Tan1, Kylie Staggard1, Tessa O'Halloran1, Huong Xuan Thi Nguyen1, Jessica Disler1, Frances Crotty1, Kai Lim1, Joseph Cianter1, Cate Kelly5, Kwang Lim1.   

Abstract

BACKGROUND: In July 2020, a COVID-19 outbreak was recognised in the geriatric wards at a subacute campus of the Royal Melbourne Hospital affecting patients and staff. Patients were also admitted to this site after diagnosis in residential care. AIMS: To describe the early symptoms and the outcomes of COVID-19 in older adults.
METHODS: Patients diagnosed with COVID-19 at the facility in July or August 2020 were identified and their medical records were examined to identify symptoms present before and after their diagnosis and to determine their outcomes.
RESULTS: Overall, 106 patients were identified as having COVID-19, with median age of 84.3 years (range 41-104 years); 64 were diagnosed as hospital inpatients after a median length of stay of 49 days, 31 were transferred from residential aged care facilities with a known diagnosis and 11 were diagnosed after discharge. There were 95 patients included in an analysis of symptom type and timing onset. Overall, 61 (64.2%) were asymptomatic at the time of diagnosis of COVID-19, having been diagnosed through screening initiated on site. Of these, 88.6% developed symptoms of COVID-19 within 14 days. The most common initial symptom type was respiratory, but there was wide variation in presentation, including fever, gastrointestinal and neurological symptoms, many initially not recognised as being due to COVID-19. Of 104 patients, 32 died within 30 days of diagnosis.
CONCLUSIONS: COVID-19 diagnosis is challenging due to the variance in symptoms. In the context of an outbreak, asymptomatic screening can identify affected patients early in the disease course.
© 2021 Royal Australasian College of Physicians.

Entities:  

Keywords:  COVID-19; aged; cohort study; coronavirus infection/diagnosis; disease transmission

Mesh:

Year:  2021        PMID: 33724644     DOI: 10.1111/imj.15286

Source DB:  PubMed          Journal:  Intern Med J        ISSN: 1444-0903            Impact factor:   2.048


  2 in total

1.  Attitudes toward COVID-19 vaccination and willingness to pay: comparison of people with and without mental disorders in China.

Authors:  Fengyi Hao; Bokun Wang; Wanqiu Tan; Syeda Fabeha Husain; Roger S McIntyre; Xiangdong Tang; Ling Zhang; Xiaofan Han; Li Jiang; Nicholas W S Chew; Benjamin Yong-Qiang Tan; Bach Tran; Zhisong Zhang; Gia Linh Vu; Giang Thu Vu; Roger Ho; Cyrus S Ho; Vijay K Sharma
Journal:  BJPsych Open       Date:  2021-08-11

2.  Advocacy for COVID-19 vaccination at perioperative consultations: an opportunity for protection.

Authors:  Ned Douglas; Katherine Gregorevic; Mandy Law; Benjamin N J Thomson; Douglas F Johnson
Journal:  ANZ J Surg       Date:  2021-07-12       Impact factor: 2.025

  2 in total

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