Renato Maluta1, Mabelle Freitas Monteiro2, Daiane Cristina Peruzzo1, Julio Cesar Joly3. 1. Implantology and Periodontology, São Leopoldo Mandic Research Institute, R. Dr. José Rocha Junqueira, 13 - Pte. Preta, Campinas, SP, 13045-755, Brazil. 2. Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Av. Limeira, 901 - Areião, Piracicaba, SP, 13414-903, Brazil. 3. Implantology and Periodontology, São Leopoldo Mandic Research Institute, R. Dr. José Rocha Junqueira, 13 - Pte. Preta, Campinas, SP, 13045-755, Brazil. joly@implanteperio.com.br.
Abstract
OBJECTIVES: This study aimed to compare xenogeneic dermal matrix (XDM) to connective tissue graft (CTG) associated with coronally advanced flap (CAF) in treating Miller's class I and II (RT1) multiple gingival recession in a split-mouth randomized clinical trial. MATERIALS AND METHODS:Fifteen patients with bilateral Miller's class I and II multiple recessions were selected. The patient's side receiving each treatment was randomly allocated to receive XDM or CTG. The clinical parameters were measured at baseline and 6 months of follow-up. RESULTS: At 6 months, no significant difference in the root coverage (RC) (95.28 ± 6.89% for CTG and 92.68 ± 7.35% for XDM) and the keratinized tissue (KT) gain (0.91 ± 0.46 mm for CTG and 0.74 ± 0.39 mm for XDM) was observed between groups (p > 0.05). The CTG group presented higher complete root coverage (CRC) than XDM (60% and 33%, respectively) (p = 0.045). Multiple logistic regression indicated that the XDM (p = 0.01) and the XDM and KT interaction (p = 0.02) negatively interfered in the CRC. A 1-mm increase in the baseline KT when using XDM increases almost 6 times the chance of achieving CRC, and XDM reached a similar CRC probability to CTG when the receptor area presented at least 2 mm of KT. CONCLUSIONS: Both treatments were effective for treating multiple gingival recession; similar KT gain, GR reduction, and RC were obtained for CTG and XDM, while CTG promoted higher CRC than XDM. Moreover, the amount of KT at baseline was determinant for CRC when treating multiple gingival recession with XDM. CLINICAL RELEVANCE: XDM produces limited CRC in sites with a reduced amount of KT. TRIAL REGISTRATION: Brazilian Clinical Trials Registry (REBEC) number RBR-56NZQ6.
RCT Entities:
OBJECTIVES: This study aimed to compare xenogeneic dermal matrix (XDM) to connective tissue graft (CTG) associated with coronally advanced flap (CAF) in treating Miller's class I and II (RT1) multiple gingival recession in a split-mouth randomized clinical trial. MATERIALS AND METHODS: Fifteen patients with bilateral Miller's class I and II multiple recessions were selected. The patient's side receiving each treatment was randomly allocated to receive XDM or CTG. The clinical parameters were measured at baseline and 6 months of follow-up. RESULTS: At 6 months, no significant difference in the root coverage (RC) (95.28 ± 6.89% for CTG and 92.68 ± 7.35% for XDM) and the keratinized tissue (KT) gain (0.91 ± 0.46 mm for CTG and 0.74 ± 0.39 mm for XDM) was observed between groups (p > 0.05). The CTG group presented higher complete root coverage (CRC) than XDM (60% and 33%, respectively) (p = 0.045). Multiple logistic regression indicated that the XDM (p = 0.01) and the XDM and KT interaction (p = 0.02) negatively interfered in the CRC. A 1-mm increase in the baseline KT when using XDM increases almost 6 times the chance of achieving CRC, and XDM reached a similar CRC probability to CTG when the receptor area presented at least 2 mm of KT. CONCLUSIONS: Both treatments were effective for treating multiple gingival recession; similar KT gain, GR reduction, and RC were obtained for CTG and XDM, while CTG promoted higher CRC than XDM. Moreover, the amount of KT at baseline was determinant for CRC when treating multiple gingival recession with XDM. CLINICAL RELEVANCE: XDM produces limited CRC in sites with a reduced amount of KT. TRIAL REGISTRATION: Brazilian Clinical Trials Registry (REBEC) number RBR-56NZQ6.
Authors: A M Pabst; W Wagner; A Kasaj; S Gebhardt; M Ackermann; A Astolfo; F Marone; D Haberthür; F Enzmann; Moritz A Konerding Journal: Clin Oral Investig Date: 2014-09-11 Impact factor: 3.573
Authors: Christian M Schmitt; Ragai E Matta; Tobias Moest; Julia Humann; Lisa Gammel; Friedrich W Neukam; Karl A Schlegel Journal: J Clin Periodontol Date: 2016-05-19 Impact factor: 8.728
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