Yoshinori Takayanagi1, Shigeaki Kato2,3, Masaru Okada4. 1. Takayanagi EYE Clinic, Sapporo S1 Building 3F, Nishi4-20-5, Minami1-jo, Chuo-ku, Sapporo, Hokkaido, 060-0807, Japan. takayanagi@carnamed.jp. 2. Graduate School of Science and Engineering, Iryo Sosei University, 5-5-1, Iino, Chuo-dai, Iwaki, Fukushima, 970-8551, Japan. uskato0525@gmail.com. 3. Research Institute of Innovative Medicine, Tokiwa Foundation, 57 Kaminodai, Jyoban Kamiyunagayamachi, Iwaki, Fukushima, 972-8322, Japan. uskato0525@gmail.com. 4. Takayanagi EYE Clinic, Sapporo S1 Building 3F, Nishi4-20-5, Minami1-jo, Chuo-ku, Sapporo, Hokkaido, 060-0807, Japan.
Abstract
BACKGROUND: Corneal refractive surgeries cause epithelial damage and induce wound healing processes. To promote wound healing after photorefractive keratectomy, the effectiveness of an autologous platelet tissue graft was assessed. CASE PRESENTATION: A 45-year-old Asian male with low myopia and/or myopic astigmatism received photorefractive keratectomy in both eyes. The right eye was postoperatively treated with an autologous platelet tissue graft using the GPS III Platelet Concentration System to prepare platelet-rich plasma, while the left eye was not treated. Both eyes achieved the expected uncorrected distance visual acuity, but the platelet-rich-plasma-treated right eye obtained improved visual acuity more than 1 week before the untreated left eye. Perceived pain after photorefractive keratectomy was much lower and of shorter duration in the treated right eye than it was for the left eye. Pericorneal injection on the bulbar conjunctiva with superficial keratitis resolved earlier in the right eye than the left eye. CONCLUSIONS: Autologous platelet tissue grafting using a GPS III to obtain platelet-rich plasma was effective in promoting corneal wound healing after photorefractive keratectomy. Thus, platelet-rich plasma may be beneficial for patients undergoing corneal refractive surgeries.
BACKGROUND:Corneal refractive surgeries cause epithelial damage and induce wound healing processes. To promote wound healing after photorefractive keratectomy, the effectiveness of an autologous platelet tissue graft was assessed. CASE PRESENTATION: A 45-year-old Asian male with low myopia and/or myopic astigmatism received photorefractive keratectomy in both eyes. The right eye was postoperatively treated with an autologous platelet tissue graft using the GPS III Platelet Concentration System to prepare platelet-rich plasma, while the left eye was not treated. Both eyes achieved the expected uncorrected distance visual acuity, but the platelet-rich-plasma-treated right eye obtained improved visual acuity more than 1 week before the untreated left eye. Perceived pain after photorefractive keratectomy was much lower and of shorter duration in the treated right eye than it was for the left eye. Pericorneal injection on the bulbar conjunctiva with superficial keratitis resolved earlier in the right eye than the left eye. CONCLUSIONS: Autologous platelet tissue grafting using a GPS III to obtain platelet-rich plasma was effective in promoting corneal wound healing after photorefractive keratectomy. Thus, platelet-rich plasma may be beneficial for patients undergoing corneal refractive surgeries.
Authors: Thøger Persson Krogh; Ulrich Fredberg; Kristian Stengaard-Pedersen; Robin Christensen; Pia Jensen; Torkell Ellingsen Journal: Am J Sports Med Date: 2013-01-17 Impact factor: 6.202