Literature DB >> 33720764

Early Operative Versus Delayed Operative Versus Nonoperative Treatment of Pediatric and Adolescent Anterior Cruciate Ligament Injuries: A Systematic Review and Meta-analysis.

Evan W James1, Brody J Dawkins1, Jonathan M Schachne1, Theodore J Ganley1, Mininder S Kocher1, Christian N Anderson1, Michael T Busch1, Henry G Chambers1, Melissa A Christino1, Frank A Cordasco1, Eric W Edmonds1, Daniel W Green1, Benton E Heyworth1, J Todd R Lawrence1, Lyle J Micheli1, Matthew D Milewski1, Matthew J Matava1, Jeffrey J Nepple1, Shital N Parikh1, Andrew T Pennock1, Crystal A Perkins1, Paul M Saluan1, Kevin G Shea1, Eric J Wall1, Samuel C Willimon1, Peter D Fabricant1.   

Abstract

BACKGROUND: Treatment options for pediatric and adolescent anterior cruciate ligament (ACL) injuries include early operative, delayed operative, and nonoperative management. Currently, there is a lack of consensus regarding the optimal treatment for these injuries. PURPOSE/HYPOTHESIS: The purpose was to determine the optimal treatment strategy for ACL injuries in pediatric and adolescent patients. We hypothesized that (1) early ACL reconstruction results in fewer meniscal tears than delayed reconstruction but yields no difference in knee stability and (2) when compared with nonoperative management, any operative management results in fewer meniscal tears and cartilage injuries, greater knee stability, and higher return-to-sport rates. STUDY
DESIGN: Systematic review and meta-analysis; Level of evidence, 4.
METHODS: A systematic search of databases was performed including PubMed, Embase, and Cochrane Library using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Inclusion criteria were a pediatric and adolescent patient population (≤19 years old at surgery), the reporting of clinical outcomes after treatment of primary ACL injury, and original scientific research article. Exclusion criteria were revision ACL reconstruction, tibial spine avulsion fracture, case report or small case series (<5 patients), non-English language manuscripts, multiligamentous injuries, and nonclinical studies.
RESULTS: A total of 30 studies containing 50 cohorts and representing 1176 patients met our criteria. With respect to nonoperative treatment, knee instability was observed in 20% to 100%, and return to preinjury level of sports ranged from 6% to 50% at final follow-up. Regarding operative treatment, meta-analysis results favored early ACL reconstruction over delayed reconstruction (>12 weeks) for the presence of any meniscal tear (odds ratio, 0.23; P = .006) and irreparable meniscal tear (odds ratio, 0.31; P = .001). Comparison of any side-to-side differences in KT-1000 arthrometer testing did not favor early or delayed ACL reconstruction in either continuous mean differences (P = .413) or proportion with difference ≥3 mm (P = .181). Return to preinjury level of competition rates for early and delayed ACL reconstruction ranged from 57% to 100%.
CONCLUSION: Delaying ACL reconstruction in pediatric or adolescent patients for >12 weeks significantly increased the risk of meniscal injuries and irreparable meniscal tears; however, early and delayed operative treatment achieved satisfactory knee stability. Nonoperative management resulted in high rates of residual knee instability, increased risk of meniscal tears, and comparatively low rates of return to sports.

Entities:  

Keywords:  ACL reconstruction; adolescent; knee instability; meniscal tear; meta-analysis; nonoperative management; outcomes; pediatric; systematic review

Mesh:

Year:  2021        PMID: 33720764     DOI: 10.1177/0363546521990817

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  8 in total

Review 1.  "Cost-effectiveness of ACL treatment is dependent on age and activity level: a systematic review".

Authors:  R Deviandri; H C van der Veen; A M T Lubis; I van den Akker-Scheek; M J Postma
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2022-08-23       Impact factor: 4.114

2.  Long-term evaluation of pediatric ACL reconstruction: high risk of further surgery but a restrictive postoperative management was related to a lower revision rate.

Authors:  Frida Hansson; Eva Bengtsson Moström; Magnus Forssblad; Anders Stålman; Per-Mats Janarv
Journal:  Arch Orthop Trauma Surg       Date:  2021-08-30       Impact factor: 2.928

3.  Wide Variability of Pediatric Knee Arthroscopy Case Volume in Orthopaedic Surgery Residency.

Authors:  Suleiman Y Sudah; David S Constantinescu; Matthew H Nasra; Christopher R Michel; Christopher N Dijanic; Daniel J Kerrigan; Ryan J Plyler
Journal:  Arthrosc Sports Med Rehabil       Date:  2021-09-14

4.  Sensitivity and Specificity of MRI in Diagnosing Concomitant Meniscal Injuries With Pediatric and Adolescent Acute ACL Tears.

Authors:  Brody J Dawkins; David A Kolin; Joshua Park; Peter D Fabricant; Allison Gilmore; Mark Seeley; R Justin Mistovich
Journal:  Orthop J Sports Med       Date:  2022-03-09

5.  Trends in Anterolateral Ligament Reconstruction and Lateral Extra-articular Tenodesis With ACL Reconstruction in Children and Adolescents.

Authors:  Ashwin S Madhan; Theodore J Ganley; Scott D McKay; Nirav K Pandya; Neeraj M Patel
Journal:  Orthop J Sports Med       Date:  2022-04-06

6.  Unique Considerations for the Pediatric Athlete During Rehabilitation and Return to Sport After Anterior Cruciate Ligament Reconstruction.

Authors:  Yukiko Matsuzaki; Danielle E Chipman; Sofia Hidalgo Perea; Daniel W Green
Journal:  Arthrosc Sports Med Rehabil       Date:  2022-01-28

7.  Outcomes, Including Graft Tears, Contralateral Anterior Cruciate Ligament Tears, and All-Cause Ipsilateral Knee Operations, are Similar for Adult-type, Transphyseal, and Partial Transphyseal Anterior Cruciate Ligament Reconstruction Using Hamstring Autograft in Pediatric and Adolescent Patients.

Authors:  Sachin Allahabadi; Ashish Mittal; Monica J Coughlan; Arin E Kim; Nicole J Hung; Nirav K Pandya
Journal:  Arthrosc Sports Med Rehabil       Date:  2022-07-11

8.  Single versus double hamstring tendon graft in anterior cruciate ligament reconstruction in the paediatric patient: a single-blind randomised controlled trial study protocol.

Authors:  David Bade; Garrett Malayko; Liam Johnson; Kylie Bradford; Tristan Reddan; Chris Stockton; Kieran Frawley; Teresa Phillips; David Saxby; Robert S Ware; Joshua Byrnes; Christopher P Carty
Journal:  BMJ Open       Date:  2022-08-19       Impact factor: 3.006

  8 in total

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