Yannick Stephan1, Angelina R Sutin2, Brice Canada3, Antonio Terracciano4. 1. Euromov, University of Montpelier, Montpelier, France. 2. Department of Behavioral Sciences and Social Medicine, College of Medicine, Florida State University, Tallahassee, Florida, USA. 3. L-VIS, University of Lyon 1, Lyon, France. 4. Department of Geriatrics, College of Medicine, Florida State University, Tallahassee, Florida, USA.
Abstract
OBJECTIVES: The motoric cognitive risk (MCR) syndrome, characterized by cognitive complaints and slower gait speed, is a predementia syndrome associated with dementia and mortality risk. The present study examined whether subjective age, that is, how old or young individuals feel relative to their chronological age, is related to concurrent and incident MCR syndrome. A relation between subjective age and MCR will inform knowledge on psychological factors related to dementia risk, identify who is at greater risk, and suggest a potential target of intervention. METHODS: The study sample was composed of 6,341 individuals aged 65-107 years without dementia from the Health and Retirement Study, a longitudinal study of adults aged 50 years and older. Participants completed measures of subjective age, cognitive complaints, and gait speed and provided information on demographic factors, cognition, physical activity, depressive symptoms, and body mass index (BMI) at baseline in 2008/2010. Incident MCR was assessed 4 and 8 years later. RESULTS: Controlling for demographic factors, an older subjective age was related to more than 60% higher likelihood of MCR at baseline and to around 50% higher risk of incident MCR over time. These associations remained significant when cognition, physical inactivity, depressive symptoms, and BMI were included in the analytic models. DISCUSSION: This study provides evidence that how old individuals feel is related to concurrent and incident MCR beyond the effect of chronological age, other demographic factors, physical inactivity, depressive symptoms, BMI, and cognitive functioning.
OBJECTIVES: The motoric cognitive risk (MCR) syndrome, characterized by cognitive complaints and slower gait speed, is a predementia syndrome associated with dementia and mortality risk. The present study examined whether subjective age, that is, how old or young individuals feel relative to their chronological age, is related to concurrent and incident MCR syndrome. A relation between subjective age and MCR will inform knowledge on psychological factors related to dementia risk, identify who is at greater risk, and suggest a potential target of intervention. METHODS: The study sample was composed of 6,341 individuals aged 65-107 years without dementia from the Health and Retirement Study, a longitudinal study of adults aged 50 years and older. Participants completed measures of subjective age, cognitive complaints, and gait speed and provided information on demographic factors, cognition, physical activity, depressive symptoms, and body mass index (BMI) at baseline in 2008/2010. Incident MCR was assessed 4 and 8 years later. RESULTS: Controlling for demographic factors, an older subjective age was related to more than 60% higher likelihood of MCR at baseline and to around 50% higher risk of incident MCR over time. These associations remained significant when cognition, physical inactivity, depressive symptoms, and BMI were included in the analytic models. DISCUSSION: This study provides evidence that how old individuals feel is related to concurrent and incident MCR beyond the effect of chronological age, other demographic factors, physical inactivity, depressive symptoms, BMI, and cognitive functioning.
Authors: Joe Verghese; Cedric Annweiler; Emmeline Ayers; Nir Barzilai; Olivier Beauchet; David A Bennett; Stephanie A Bridenbaugh; Aron S Buchman; Michele L Callisaya; Richard Camicioli; Benjamin Capistrant; Somnath Chatterji; Anne-Marie De Cock; Luigi Ferrucci; Nir Giladi; Jack M Guralnik; Jeffrey M Hausdorff; Roee Holtzer; Ki Woong Kim; Paul Kowal; Reto W Kressig; Jae-Young Lim; Susan Lord; Kenichi Meguro; Manuel Montero-Odasso; Susan W Muir-Hunter; Mohan L Noone; Lynn Rochester; Velandai Srikanth; Cuiling Wang Journal: Neurology Date: 2014-07-16 Impact factor: 9.910
Authors: Fiachra J Maguire; Isabelle Killane; Andrew P Creagh; Orna Donoghue; Rose Anne Kenny; Richard B Reilly Journal: J Am Med Dir Assoc Date: 2017-09-09 Impact factor: 4.669