| Literature DB >> 33718692 |
Matthew Alonzo1,2, Fabian Alvarez Primo1,2, Shweta Anil Kumar1,2, Joel A Mudloff1,2, Erick Dominguez1,3, Gisel Fregoso1,4, Nick Ortiz1,5, William M Weiss6, Binata Joddar1,2,7.
Abstract
Bone tissue engineering (BTE) aims to develop strategies to regenerate damaged or diseased bone using a combination of cells, growth factors, and biomaterials. This article highlights recent advances in BTE, with particular emphasis on the role of the biomaterials as scaffolding material to heal bone defects. Studies encompass the utilization of bioceramics, composites, and myriad hydrogels that have been fashioned by injection molding, electrospinning, and 3D bioprinting over recent years, with the aim to provide an insight into the progress of BTE along with a commentary on their scope and possibilities to aid future research. The biocompatibility and structural efficacy of some of these biomaterials are also discussed.Entities:
Keywords: 3D printing; bone defect; electrospinning; injection molding; orthopedics; tissue engineering
Year: 2020 PMID: 33718692 PMCID: PMC7948130 DOI: 10.1016/j.cobme.2020.100248
Source DB: PubMed Journal: Curr Opin Biomed Eng ISSN: 2468-4511