Literature DB >> 33718629

Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats.

Shaikh Shahinur Rahman1, Hussain Mohammad Salauddin1, Mahfuzur Rahman2, Mir Mohammad Muhsin1, Shakh Ma Rouf1.   

Abstract

Diabetic patients usually avoid germinated endosperm of sugar palm (GESP) and elephant foot yam tuber (EFYT), fearing that these may further deteriorate existing hyperglycemia. In the present study, this suspicion was investigated by analyzing the nutrients and following the animal experiments by supplementary feeding powder of GESP, EFYT, and their mixture in addition to the regular diet for the six consecutive weeks. Next three weeks, the powder was withdrawn, and fasting blood glucose (FBG) levels were recorded from the beginning. The results clearly showed that these foodstuffs significantly (P < 0.001) reduced FBG levels of alloxan-induced diabetic rats. The mixture of GESP & EFYT showed the maximum antidiabetic effects followed by GESP and EFYT, respectively. GESP, as well as the mixture, returned the FBG levels of diabetic rats within the normal range by the end of the 6th week, even after withdrawing the powder, but not by the EFYT. These results suggested that the foodstuffs may restore the damaged pancreatic β-cell functions by the end of the 6th week. Nutrient contents like fiber, zinc, as well as antidiabetogenic phytochemicals present in these foodstuffs, could perform these functions.
© 2021 The Authors. Published by Elsevier B.V.

Entities:  

Keywords:  Antidiabetic; Elephant foot yam; Germinated endosperm; Nutrients; Rats; Sugar palm

Year:  2021        PMID: 33718629      PMCID: PMC7923245          DOI: 10.1016/j.bbrep.2021.100917

Source DB:  PubMed          Journal:  Biochem Biophys Rep        ISSN: 2405-5808


  10 in total

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Authors:  Gopalsamy Rajiv Gandhi; Savarimuthu Ignacimuthu; Michael Gabriel Paulraj
Journal:  Food Chem Toxicol       Date:  2012-01-30       Impact factor: 6.023

2.  Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity.

Authors:  H Kaneto; Y Kajimoto; J Miyagawa; T Matsuoka; Y Fujitani; Y Umayahara; T Hanafusa; Y Matsuzawa; Y Yamasaki; M Hori
Journal:  Diabetes       Date:  1999-12       Impact factor: 9.461

3.  Is elephant foot yam (Amorphophallus paeoniifolius) tuber detrimental to patients with diabetes? (Or a myth?).

Authors:  Shaikh Shahinur Rahman
Journal:  Diabetes Metab Syndr       Date:  2020-06-26

4.  Bioactive components from flowers of Sambucus nigra L. increase glucose uptake in primary porcine myotube cultures and reduce fat accumulation in Caenorhabditis elegans.

Authors:  Sumangala Bhattacharya; Kathrine B Christensen; Louise C B Olsen; Lars P Christensen; Kai Grevsen; Nils J Færgeman; Karsten Kristiansen; Jette F Young; Niels Oksbjerg
Journal:  J Agric Food Chem       Date:  2013-11-07       Impact factor: 5.279

5.  Antidiabetic activity of Terminalia sericea constituents.

Authors:  Nolitha Nkobole; Peter James Houghton; Ahmed Hussein; Namrita Lall
Journal:  Nat Prod Commun       Date:  2011-11       Impact factor: 0.986

6.  Glucose uptake stimulatory effect of 4-hydroxypipecolic acid by increased GLUT 4 translocation in skeletal muscle cells.

Authors:  G Naresh; N Jaiswal; P Sukanya; A K Srivastava; A K Tamrakar; T Narender
Journal:  Bioorg Med Chem Lett       Date:  2012-07-11       Impact factor: 2.823

7.  Anti-hyperglycemic effect of the immature endosperm of sugar palm (Borassus flabellifer) fruit on type 2 diabetes mellitus patients-a case study.

Authors:  Shaikh Shahinur Rahman; Nilufar Yasmin; Md Kamruzzaman; Md Rezwanul Islam; Md Rezaul Karim; Shakh Ma Rouf
Journal:  Diabetes Metab Syndr       Date:  2020-07-09

8.  Role of zinc in insulin biosynthesis. Some possible zinc-insulin interactions in the pancreatic B-cell.

Authors:  S O Emdin; G G Dodson; J M Cutfield; S M Cutfield
Journal:  Diabetologia       Date:  1980-09       Impact factor: 10.122

9.  Beneficial effect of Amorphophallus paeoniifolius tuber on experimental ulcerative colitis in rats.

Authors:  Yadu Nandan Dey; Garima Sharma; Manish M Wanjari; Dharmendra Kumar; Vinay Lomash; Ankush D Jadhav
Journal:  Pharm Biol       Date:  2016-09-07       Impact factor: 3.503

10.  Phytochemical constituents, nutritional values, phenolics, flavonols, flavonoids, antioxidant and cytotoxicity studies on Phaleria macrocarpa (Scheff.) Boerl fruits.

Authors:  Ma Ma Lay; Saiful Anuar Karsani; Sadegh Mohajer; Sri Nurestri Abd Malek
Journal:  BMC Complement Altern Med       Date:  2014-05-08       Impact factor: 3.659

  10 in total

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