Literature DB >> 33718282

Clinical and Laboratory Profile of Hospitalized Symptomatic COVID-19 Patients: Case Series Study From the First COVID-19 Center in the UAE.

Suad Hannawi1, Haifa Hannawi1,2, Kashif Bin Naeem1, Noha Mousaad Elemam3,4, Mahmood Y Hachim5, Ibrahim Y Hachim3,4, Abdulla Salah Darwish6, Issa Al Salmi7,8.   

Abstract

Introduction: COVID-19 is raising with a second wave threatening many countries. Therefore, it is important to understand COVID-19 characteristics across different countries.
Methods: This is a cross-sectional descriptive study of 525 hospitalized symptomatic COVID-19 patients, from the central federal hospital in Dubai-UAE during period of March to August 2020.
Results: UAE's COVID-19 patients were relatively young; mean (SD) of the age 49(15) years, 130 (25%) were older than 60 and 4 (<1%) were younger than 18 years old. Majority were male(47; 78%). The mean (SD) BMI was 29 (6) kg/m2. While the source of contracting COVID-19 was not known in 369 (70%) of patients, 29 (6%) reported travel to overseas-country and 127 (24%) reported contact with another COVID-19 case/s. At least one comorbidity was present in 284 (54%) of patients and 241 (46%) had none. The most common comorbidities were diabetes (177; 34%) and hypertension (166; 32%). The mean (SD) of symptoms duration was 6 (3) days. The most common symptoms at hospitalization were fever (340; 65%), cough (296; 56%), and shortness of breath (SOB) (243; 46%). Most of the laboratory values were within normal range, but (184; 35%) of patients had lymphopenia, 43 (8%) had neutrophilia, and 116 (22%) had prolong international normalized ratio (INR), and 317 (60%) had high D-dimer. Chest x ray findings of consolidation was present in 334 (64%) of patients and CT scan ground glass appearance was present in 354 (68%). Acute cardiac injury occurred in 124 (24%), acute kidney injury in 111 (21%), liver injury in 101 (19%), ARDS in 155 (30%), acidosis in 118 (22%), and septic shock in 93 (18%). Consequently, 150 (29%) required ICU admission with 103 (20%) needed mechanical ventilation. Conclusions: The study demonstrated the special profile of COVID-19 in UAE. Patients were young with diabetes and/or hypertension and associated with severe infection as shown by various clinical and laboratory data necessitating ICU admission.
Copyright © 2021 Hannawi, Hannawi, Naeem, Elemam, Hachim, Hachim, Darwish and Al Salmi.

Entities:  

Keywords:  COVID-19; acute respiratory distress syndrome; clinical characteristics; laboratory features; mechanical ventilation; organ failure

Mesh:

Year:  2021        PMID: 33718282      PMCID: PMC7952884          DOI: 10.3389/fcimb.2021.632965

Source DB:  PubMed          Journal:  Front Cell Infect Microbiol        ISSN: 2235-2988            Impact factor:   5.293


  44 in total

Review 1.  Hypertension prevalence, awareness, and control in Arab countries: a systematic review.

Authors:  Ayman Tailakh; Lorraine S Evangelista; Janet C Mentes; Nancy A Pike; Linda R Phillips; Donald E Morisky
Journal:  Nurs Health Sci       Date:  2013-09-30       Impact factor: 1.857

Review 2.  Potential Antiviral Drugs for SARS-Cov-2 Treatment: Preclinical Findings and Ongoing Clinical Research.

Authors:  Sabrina Bimonte; Anna Crispo; Alfonso Amore; Egidio Celentano; Arturo Cuomo; Marco Cascella
Journal:  In Vivo       Date:  2020-06       Impact factor: 2.155

3.  COVID-19 experience in Kuwait: A high prevalence of asymptomatic cases and increased mortality in smokers.

Authors:  Awadhesh Kumar Singh
Journal:  EClinicalMedicine       Date:  2020-07-14

Review 4.  Trends in the prevalence of type 2 diabetes mellitus and obesity in the Arabian Gulf States: systematic review and meta-analysis.

Authors:  Nouf Sahal Alharbi; Reem Almutari; Simon Jones; Nasser Al-Daghri; Kamlesh Khunti; Simon de Lusignan
Journal:  Diabetes Res Clin Pract       Date:  2014-09-06       Impact factor: 5.602

5.  A novel coronavirus outbreak of global health concern.

Authors:  Chen Wang; Peter W Horby; Frederick G Hayden; George F Gao
Journal:  Lancet       Date:  2020-01-24       Impact factor: 79.321

6.  Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients. A single-center experience.

Authors:  Kashif B Naeem; Mahmood Y Hachim; Ibrahim Y Hachim; Ayman Chkhis; Rajesh Quadros; Haifa Hannawi; Issa Al Salmi; Fahdah Alokaily; Suad Hannawi
Journal:  Saudi Med J       Date:  2020-11       Impact factor: 1.484

7.  Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis.

Authors:  Leiwen Fu; Bingyi Wang; Tanwei Yuan; Xiaoting Chen; Yunlong Ao; Thomas Fitzpatrick; Peiyang Li; Yiguo Zhou; Yi-Fan Lin; Qibin Duan; Ganfeng Luo; Song Fan; Yong Lu; Anping Feng; Yuewei Zhan; Bowen Liang; Weiping Cai; Lin Zhang; Xiangjun Du; Linghua Li; Yuelong Shu; Huachun Zou
Journal:  J Infect       Date:  2020-04-10       Impact factor: 6.072

8.  Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro.

Authors:  Jia Liu; Ruiyuan Cao; Mingyue Xu; Xi Wang; Huanyu Zhang; Hengrui Hu; Yufeng Li; Zhihong Hu; Wu Zhong; Manli Wang
Journal:  Cell Discov       Date:  2020-03-18       Impact factor: 10.849

9.  Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention.

Authors:  Zunyou Wu; Jennifer M McGoogan
Journal:  JAMA       Date:  2020-04-07       Impact factor: 56.272

Review 10.  The recent challenges of highly contagious COVID-19, causing respiratory infections: Symptoms, diagnosis, transmission, possible vaccines, animal models, and immunotherapy.

Authors:  Ranjan K Mohapatra; Lucia Pintilie; Venkataramana Kandi; Ashish K Sarangi; Debadutta Das; Raghaba Sahu; Lina Perekhoda
Journal:  Chem Biol Drug Des       Date:  2020-07-26       Impact factor: 2.873

View more
  6 in total

1.  Epidemiology, Clinico-Pathological Characteristics, and Comorbidities of SARS-CoV-2-Infected Pakistani Patients.

Authors:  Saadia Omer; Mehrunnisa Fatima Gondal; Muhammad Usman; Muhammad Bilal Sarwar; Muhammad Roman; Alam Khan; Nadeem Afzal; Tanveer Ahmed Qaiser; Muhammad Yasir; Faheem Shahzad; Romeeza Tahir; Saima Ayub; Javed Akram; Raja Muhammad Faizan; Muhammad Asif Naveed; Shah Jahan
Journal:  Front Cell Infect Microbiol       Date:  2022-05-26       Impact factor: 6.073

2.  Ferritin, blood urea nitrogen, and high chest CT score determines ICU admission in COVID-19 positive UAE patients: A single center retrospective study.

Authors:  Riyad Bendardaf; Poorna Manasa Bhamidimarri; Zainab Al-Abadla; Dima Zein; Noura Alkhayal; Ramy Refaat Georgy; Feda Al Ali; Alaa Elkhider; Sadeq Qadri; Rifat Hamoudi; Salah Abusnana
Journal:  PLoS One       Date:  2022-07-19       Impact factor: 3.752

3.  Clinical characteristics and Co-morbidities among patients admitted with COVID-19.

Authors:  Omair Al Hussain
Journal:  Ann Med Surg (Lond)       Date:  2022-05-31

4.  The inflammatory biomarkers profile of hospitalized patients with COVID-19 and its association with patient's outcome: A single centered study.

Authors:  Ibrahim Y Hachim; Mahmood Y Hachim; Haifa Hannawi; Kashif Bin Naeem; Abdulla Salah; Suad Hannawi
Journal:  PLoS One       Date:  2021-12-02       Impact factor: 3.240

Review 5.  Global data analysis and risk factors associated with morbidity and mortality of COVID-19.

Authors:  Sina Salajegheh Tazerji; Fatemeh Shahabinejad; Mahya Tokasi; Mohammad Ali Rad; Muhammad Sajjad Khan; Muhammad Safdar; Krzysztof J Filipiak; Lukasz Szarpak; Tomasz Dzieciatkowski; Jan Jurgiel; Phelipe Magalhães Duarte; Md Tanvir Rahman; Md Abdus Sobur; Md Saiful Islam; Adnan Ahmed; Mohamed N F Shaheen; Awad A Shehata; Rasha Gharieb; Mohamed Fawzy; Yashpal Singh Malik; Nagaraj Jaganathasamy; Vinodhkumar Obli Rajendran; Kannan Subbaram; P Shaik Syed Ali; Sheeza Ali; Saif Ur Rehman; Mehmet Ozaslan; Gulfaraz Khan; Muhammad Saeed; Umair Younas; Safdar Imran; Yasmeen Junejo; Parmida Arabkarami; Unarose Hogan; Alfonso J Rodriguez-Morales
Journal:  Gene Rep       Date:  2022-01-15

6.  Ethnicity-Specific Features of COVID-19 Among Arabs, Africans, South Asians, East Asians, and Caucasians in the United Arab Emirates.

Authors:  Fatmah Al Zahmi; Tetiana Habuza; Rasha Awawdeh; Hossam Elshekhali; Martin Lee; Nassim Salamin; Ruhina Sajid; Dhanya Kiran; Sanjay Nihalani; Darya Smetanina; Tatsiana Talako; Klaus Neidl-Van Gorkom; Nazar Zaki; Tom Loney; Yauhen Statsenko
Journal:  Front Cell Infect Microbiol       Date:  2022-03-16       Impact factor: 5.293

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.