Literature DB >> 33717721

A Fatal Case of Opioid Intoxication After Raw Poppy Plant Ingestion.

Gurkan Bozan1, Hasan Bora Ulukapi2, Ummuhan Oncul1, Serkan Levent3, Ener C Dinleyici1.   

Abstract

Papaver somniferum contains many opioids and is frequently used in agriculture. Both the intoxication and the withdrawal of opioids have a wide range of symptoms such as coma, depressed respiration and agitation. Here, a fatal case of opioid intoxication will be presented. A four-year-old female patient was admitted to the pediatric intensive care unit after ingesting raw poppy plants. She had shallow respiration, tachycardia, hypertension and muscle cramps. A high plasma opioid level was measured and bolus intravenous naloxone was administered which resulted in a brief gain of consciousness. She was intubated after a sudden respiratory depression and loss of consciousness 10 hours later. Naloxone infusion was started and continued for two days. She developed disseminated intravascular coagulation and was lost on day twelve. Raw plant ingestion proves difficult to treat since there is less information about the ingredients. Having no consensus on naloxone dosage and intrinsic complications such as hypo- and hypertension, redistribution, rhabdomyolysis and dysmotility disrupts naloxone administration. Ingestion of opioids as plants brings out different complications for the treatment course while deciding on naloxone dosage proves opioid intoxication difficult to treat.
Copyright © 2021, Bozan et al.

Entities:  

Keywords:  naloxone; opioids; papaver somniferum; plant alkaloids; poppy

Year:  2021        PMID: 33717721      PMCID: PMC7939539          DOI: 10.7759/cureus.13176

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  9 in total

Review 1.  Naloxone in opioid poisoning: walking the tightrope.

Authors:  S F J Clarke; P I Dargan; A L Jones
Journal:  Emerg Med J       Date:  2005-09       Impact factor: 2.740

2.  The Evolution of Recommended Naloxone Dosing for Opioid Overdose by Medical Specialty.

Authors:  Nicholas J Connors; Lewis S Nelson
Journal:  J Med Toxicol       Date:  2016-06-07

3.  Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.

Authors:  Scott L Weiss; Mark J Peters; Waleed Alhazzani; Michael S D Agus; Heidi R Flori; David P Inwald; Simon Nadel; Luregn J Schlapbach; Robert C Tasker; Andrew C Argent; Joe Brierley; Joseph Carcillo; Enitan D Carrol; Christopher L Carroll; Ira M Cheifetz; Karen Choong; Jeffry J Cies; Andrea T Cruz; Daniele De Luca; Akash Deep; Saul N Faust; Claudio Flauzino De Oliveira; Mark W Hall; Paul Ishimine; Etienne Javouhey; Koen F M Joosten; Poonam Joshi; Oliver Karam; Martin C J Kneyber; Joris Lemson; Graeme MacLaren; Nilesh M Mehta; Morten Hylander Møller; Christopher J L Newth; Trung C Nguyen; Akira Nishisaki; Mark E Nunnally; Margaret M Parker; Raina M Paul; Adrienne G Randolph; Suchitra Ranjit; Lewis H Romer; Halden F Scott; Lyvonne N Tume; Judy T Verger; Eric A Williams; Joshua Wolf; Hector R Wong; Jerry J Zimmerman; Niranjan Kissoon; Pierre Tissieres
Journal:  Intensive Care Med       Date:  2020-02       Impact factor: 17.440

4.  Death Due to Complications of Bowel Obstruction Following Raw Poppy Seed Ingestion.

Authors:  Leah M Schuppener; Robert F Corliss
Journal:  J Forensic Sci       Date:  2017-05-23       Impact factor: 1.832

Review 5.  Neonatal Opioid Withdrawal Syndrome.

Authors:  Stephen W Patrick; Wanda D Barfield; Brenda B Poindexter
Journal:  Pediatrics       Date:  2020-11       Impact factor: 7.124

Review 6.  The opioid epidemic in pediatrics: a 2020 update.

Authors:  Myron Yaster; Peggy P McNaull; Peter J Davis
Journal:  Curr Opin Anaesthesiol       Date:  2020-06       Impact factor: 2.706

7.  The revised position papers on gastric decontamination.

Authors:  Nick A Buckley; Michael Eddleston
Journal:  Clin Toxicol (Phila)       Date:  2005       Impact factor: 4.467

Review 8.  Management of Suspected Opioid Overdose With Naloxone in Out-of-Hospital Settings: A Systematic Review.

Authors:  Roger Chou; P Todd Korthuis; Dennis McCarty; Phillip O Coffin; Jessica C Griffin; Cynthia Davis-O'Reilly; Sara Grusing; Mohamud Daya
Journal:  Ann Intern Med       Date:  2017-11-28       Impact factor: 25.391

9.  Clinical and laboratory findings of rhabdomyolysis in opioid overdose patients in the intensive care unit of a poisoning center in 2014 in Iran.

Authors:  Khoshideh Babak; Arefi Mohammad; Ghorbani Mazaher; Akbarpour Samaneh; Taghizadeh Fatemeh
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  9 in total

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