Literature DB >> 33717646

Circular RNA in tumor metastasis.

Chao Zhang1,2,3, RongFang Ding4, YiCheng Sun1,2, Si Tong Huo5,6, Alina He3,7, Chang Wen1,2, HongHao Chen1,2, William W Du3,7, WeiNan Lai8, Huijun Wang2.   

Abstract

Circular RNAs (circRNAs) are a type of endogenous non-coding RNA that were discovered to regulate gene expression through multiple pathways. Metastasis remains one of the biggest obstacles in cancer treatment. In this review, we focus on circRNAs involved in cancer tumorigenesis and metastasis. We present recently identified tumor-related circRNAs and discuss their functioning in tumor progression and metastasis. These circRNAs are categorized into different functional mechanisms, including microRNA (miRNA) sponging, protein binding, regulation of host genes, translation of circRNAs, and exosomal circRNAs. Additionally, the indirect functions of circRNAs that regulate epithelial-mesenchymal transition and autophagy are also discussed.
© 2021 The Authors.

Entities:  

Keywords:  cancer; circular RNA; gene regulation; metastasis

Year:  2021        PMID： 33717646      PMCID： PMC7907675          DOI： 10.1016/j.omtn.2021.01.032

Source DB:  PubMed          Journal:  Mol Ther Nucleic Acids        ISSN： 2162-2531            Impact factor:   8.886


  106 in total

1.  circRNA_0025202 Regulates Tamoxifen Sensitivity and Tumor Progression via Regulating the miR-182-5p/FOXO3a Axis in Breast Cancer.

Authors:  Yuting Sang; Bing Chen; Xiaojin Song; Yaming Li; Yiran Liang; Dianwen Han; Ning Zhang; Hanwen Zhang; Ying Liu; Tong Chen; Chen Li; Lijuan Wang; Wenjing Zhao; Qifeng Yang
Journal:  Mol Ther       Date:  2019-05-17       Impact factor: 11.454

2.  circRNA biogenesis competes with pre-mRNA splicing.

Authors:  Reut Ashwal-Fluss; Markus Meyer; Nagarjuna Reddy Pamudurti; Andranik Ivanov; Osnat Bartok; Mor Hanan; Naveh Evantal; Sebastian Memczak; Nikolaus Rajewsky; Sebastian Kadener
Journal:  Mol Cell       Date:  2014-09-18       Impact factor: 17.970

3.  Decreased expression of hsa_circ_001988 in colorectal cancer and its clinical significances.

Authors:  Xuning Wang; Yue Zhang; Liang Huang; Jiajin Zhang; Fei Pan; Bing Li; Yongfeng Yan; Baoqing Jia; Hongyi Liu; Shiyou Li; Wei Zheng
Journal:  Int J Clin Exp Pathol       Date:  2015-12-01

4.  Exosome circ_0044516 promotes prostate cancer cell proliferation and metastasis as a potential biomarker.

Authors:  Tian Li; Xiangzhou Sun; Liheng Chen
Journal:  J Cell Biochem       Date:  2019-10-17       Impact factor: 4.429

5.  Expression Patterns of Circular RNAs from Primary Kinase Transcripts in the Mammary Glands of Lactating Rats.

Authors:  ChunLei Zhang; Hui Wu; YanHong Wang; YuLong Zhao; XingTang Fang; CaiFa Chen; Hong Chen
Journal:  J Breast Cancer       Date:  2015-09-24       Impact factor: 3.588

6.  Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq.

Authors:  Julie L Aspden; Ying Chen Eyre-Walker; Rose J Phillips; Unum Amin; Muhammad Ali S Mumtaz; Michele Brocard; Juan-Pablo Couso
Journal:  Elife       Date:  2014-08-21       Impact factor: 8.140

7.  Circular RNA circFGFR1 promotes progression and anti-PD-1 resistance by sponging miR-381-3p in non-small cell lung cancer cells.

Authors:  Peng-Fei Zhang; Xu Pei; Ke-Sang Li; Li-Na Jin; Fei Wang; Jing Wu; Xue-Mei Zhang
Journal:  Mol Cancer       Date:  2019-12-09       Impact factor: 27.401

8.  CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7.

Authors:  Kaixuan Zeng; Xiaoxiang Chen; Mu Xu; Xiangxiang Liu; Xiuxiu Hu; Tao Xu; Huiling Sun; Yuqin Pan; Bangshun He; Shukui Wang
Journal:  Cell Death Dis       Date:  2018-04-01       Impact factor: 8.469

9.  Circular RNA circHIPK3 Promotes Cell Metastasis through miR-637/STAT3 Axis in Osteosarcoma.

Authors:  Zhongyue Huang; Chunyan Yuan; Huijie Gu; Xiangyang Cheng; Kaifeng Zhou; Jun Xu; Xiaofan Yin; Jiangni Xia
Journal:  Biomed Res Int       Date:  2020-07-24       Impact factor: 3.411

10.  Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis.

Authors:  Xiu-Yan Huang; Zi-Li Huang; Jin Huang; Bin Xu; Xin-Yu Huang; Yong-Hua Xu; Jian Zhou; Zhao-You Tang
Journal:  J Exp Clin Cancer Res       Date:  2020-01-23
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  8 in total

1.  circFBXW7 attenuates malignant progression in lung adenocarcinoma by sponging miR-942-5p.

Authors:  Yanting Dong; Tong Qiu; Yunpeng Xuan; Ao Liu; Xiao Sun; Zhangfeng Huang; Wenhao Su; Wenxing Du; Tianxiang Yun; Yang Wo; Alfons Navarro; Wenjie Jiao
Journal:  Transl Lung Cancer Res       Date:  2021-03

2.  Microarray Identifies a Key Carcinogenic Circular RNA 0008594 That Is Related to Non-Small-Cell Lung Cancer Development and Lymph Node Metastasis and Promotes NSCLC Progression by Regulating the miR-760-Mediated PI3K/AKT and MEK/ERK Pathways.

Authors:  Qiushi Wang; Chunhua Yan; Pengfei Zhang; Guanghua Li; Ruidong Zhu; Hanbing Wang; Libo Wu; Guangquan Xu
Journal:  Front Oncol       Date:  2021-11-11       Impact factor: 6.244

3.  Novel circular RNA circATRNL1 accelerates the osteosarcoma aerobic glycolysis through targeting miR-409-3p/LDHA.

Authors:  Quanbin Zhang; Lina Wang; Lili Cao; Tao Wei
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

4.  Circular RNA hsa_circ_0083756 promotes intervertebral disc degeneration by sponging miR-558 and regulating TREM1 expression.

Authors:  Xianfa Du; Shunlun Chen; Haitao Cui; Yuming Huang; Jianru Wang; Hui Liu; Zemin Li; Chunxiang Liang; Zhaomin Zheng; Hua Wang
Journal:  Cell Prolif       Date:  2022-02-21       Impact factor: 8.755

5.  Circular RNA circWWC3 augments breast cancer progression through promoting M2 macrophage polarization and tumor immune escape via regulating the expression and secretion of IL-4.

Authors:  Yang Zheng; Shuguang Ren; Yu Zhang; Sihua Liu; Lingjiao Meng; Fei Liu; Lina Gu; Ning Ai; Meixiang Sang
Journal:  Cancer Cell Int       Date:  2022-08-22       Impact factor: 6.429

Review 6.  Circle the Cardiac Remodeling With circRNAs.

Authors:  Tiqun Yang; Tianxin Long; Tailai Du; Yili Chen; Yugang Dong; Zhan-Peng Huang
Journal:  Front Cardiovasc Med       Date:  2021-06-25

7.  Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis.

Authors:  Guping Mao; Yiyang Xu; Dianbo Long; Hong Sun; Hongyi Li; Ruobin Xin; Ziji Zhang; Zhiwen Li; Zhi Yang; Yan Kang
Journal:  Stem Cell Res Ther       Date:  2021-07-13       Impact factor: 6.832

Review 8.  Emerging Role and Mechanism of circRNAs in Pediatric Malignant Solid Tumors.

Authors:  Qiyang Shen; Xingyu Liu; Wei Li; Xu Zhao; Tao Li; Kai Zhou; Jianfeng Zhou
Journal:  Front Genet       Date:  2022-01-18       Impact factor: 4.599
  8 in total

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