Literature DB >> 33715965

Ovarian transposition and cervical cancer.

Alexandros Laios1, Sara Duarte Portela2, Argyro Papadopoulou3, Ioannis D Gallos4, Mohamed Otify5, Thomas Ind6.   

Abstract

Cervical cancer is the fourth most common female malignancy worldwide. As the focus of treatment is shifting towards balancing oncological outcomes with reproductive benefit, women are becoming increasingly aware of their fertility options. Cervical cancer is one of the primary malignancies where transposition of the ovaries may be indicated. Ovarian transposition should be performed in pre-menopausal women, undergoing pelvic irradiation to preserve ovarian function and prevent early menopause. The review discusses the available literature and synthesises a concise summary for gynaecologic oncology surgeons to counsel affected women. The paradoxical controversy, leading to its under use is acknowledged, due to the scarcity of published data with regard to functional outcomes, and the lack of clinical trials. In cervical cancer, ovarian transposition remains a safe fertility preservation (FP) option, which is associated with high ovarian function preservation, an acceptable rate of ovarian cysts and a negligible risk for metastases in the transposed ovaries.
Copyright © 2021. Published by Elsevier Ltd.

Entities:  

Keywords:  Cervical cancer; Fertility preservation; Ovarian function; Ovarian transposition; Pelvic radiotherapy

Year:  2021        PMID: 33715965     DOI: 10.1016/j.bpobgyn.2021.01.013

Source DB:  PubMed          Journal:  Best Pract Res Clin Obstet Gynaecol        ISSN: 1521-6934            Impact factor:   5.237


  7 in total

1.  Laparoscopic Ovarian Transposition with Extraperitonealization of the Infundibulopelvic Ligament for Cervical Cancer in Ten Steps.

Authors:  Nicolò Bizzarri; Matteo Loverro; Martina A Angeles; Luigi Pedone Anchora; Anna Fagotti; Francesco Fanfani; Gabriella Ferrandina; Giovanni Scambia; Denis Querleu
Journal:  Ann Surg Oncol       Date:  2022-05-24       Impact factor: 4.339

Review 2.  Fertility after Cancer: Risks and Successes.

Authors:  Chiara Di Tucci; Giulia Galati; Giulia Mattei; Alessandra Chinè; Alice Fracassi; Ludovico Muzii
Journal:  Cancers (Basel)       Date:  2022-05-19       Impact factor: 6.575

3.  Ovarian Function Preservation in Patients With Cervical Cancer Undergoing Hysterectomy and Ovarian Transposition Before Pelvic Radiotherapy.

Authors:  Wonguen Jung; Yun H Kim; Kyung S Kim
Journal:  Technol Cancer Res Treat       Date:  2021 Jan-Dec

4.  Emerging Roles of m6A RNA Methylation Regulators in Gynecological Cancer.

Authors:  Wanjun Huang; Fanhua Kong; Ruolan Li; Xiang Chen; Kunpeng Wang
Journal:  Front Oncol       Date:  2022-01-28       Impact factor: 6.244

5.  Ovarian transposition in rectal cancer: uncertain benefit at a high price.

Authors:  Rebecca Fish
Journal:  Colorectal Dis       Date:  2022-03-06       Impact factor: 3.917

6.  Outcomes of ovarian transposition in cervical cancer; an updated meta-analysis.

Authors:  Alexandros Laios; Mohamed Otify; Argyro Papadopoulou; Ioannis D Gallos; Thomas Ind
Journal:  BMC Womens Health       Date:  2022-07-22       Impact factor: 2.742

Review 7.  Cisplatin for cancer therapy and overcoming chemoresistance.

Authors:  Ranmali Ranasinghe; Michael L Mathai; Anthony Zulli
Journal:  Heliyon       Date:  2022-09-14
  7 in total

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