Literature DB >> 3371476

The early results from a randomised study of radiotherapy versus Nolvadex (tamoxifen) as initial treatment for stage III breast cancer.

M R Williams1, D Gilson, L Marsh, D A Morgan, R I Nicholson, C W Elston, K Griffiths, R W Blamey.   

Abstract

Eighty-seven postmenopausal patients have been randomised to receive either radiotherapy or Nolvadex (tamoxifen) as first line treatment for locally advanced (stage III) breast cancer. After a median follow-up of two years no significant differences have been found in the rate of progression of local disease, the time to development of overt metastases or survival.

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Year:  1988        PMID: 3371476

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  8 in total

1.  Reverse gyrase in thermophilic eubacteria.

Authors:  C Bouthier de la Tour; C Portemer; R Huber; P Forterre; M Duguet
Journal:  J Bacteriol       Date:  1991-06       Impact factor: 3.490

2.  Reverse gyrase gene from Sulfolobus shibatae B12: gene structure, transcription unit and comparative sequence analysis of the two domains.

Authors:  C Jaxel; C Bouthier de la Tour; M Duguet; M Nadal
Journal:  Nucleic Acids Res       Date:  1996-12-01       Impact factor: 16.971

3.  DNA binding by the archaeal histone HMf results in positive supercoiling.

Authors:  D R Musgrave; K M Sandman; J N Reeve
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-01       Impact factor: 11.205

4.  Cellular effects of tamoxifen in primary breast cancer.

Authors:  J F Robertson; I O Ellis; R I Nicholson; A Robins; J Bell; R W Blamey
Journal:  Breast Cancer Res Treat       Date:  1992-01       Impact factor: 4.872

Review 5.  Tamoxifen. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic use.

Authors:  M M Buckley; K L Goa
Journal:  Drugs       Date:  1989-04       Impact factor: 9.546

6.  Comparison of mastectomy with tamoxifen for treating elderly patients with operable breast cancer.

Authors:  J F Robertson; J H Todd; I O Ellis; C W Elston; R W Blamey
Journal:  BMJ       Date:  1988 Aug 20-27

7.  Biological factors of prognostic significance in locally advanced breast cancer.

Authors:  J F Robertson; I O Ellis; D Pearson; C W Elston; R I Nicholson; R W Blamey
Journal:  Breast Cancer Res Treat       Date:  1994       Impact factor: 4.872

8.  pS2 protein: a marker improving prediction of response to neoadjuvant tamoxifen in post-menopausal breast cancer patients.

Authors:  I Soubeyran; N Quénel; J M Coindre; F Bonichon; M Durand; J Wafflart; L Mauriac
Journal:  Br J Cancer       Date:  1996-10       Impact factor: 7.640

  8 in total

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